[gmx-users] MD of polymer in pbc

David van der Spoel spoel at xray.bmc.uu.se
Tue Nov 26 12:23:08 CET 2002


On Tue, 2002-11-26 at 12:14, Ester Chiessi wrote:
> Hi Gromacs people,
> 
> I'm working to perform molecular dynamics simulations of a polymer in PBC and I
> found some problems.
> 
> After preliminary minimizations and preparations of the system (with no problem if
> I don't insert the connectivity accross boundaries), I received this message during
> the minimization of the 'infinite' chain:
> ...........
> Removing pbc first time.
> There were 2 inconsistent shifts. Check your topology.
> Done rmpbc.

try setting
setenv GMXFULLPBC 1

if you have an inifinite molecule (i.e. circular)



> ...........
> I tried the following dynamics that couldn't start.
> 
> This is part of the output file md0.log :
> 
> There are: 355 Atom
> Removing pbc first time
> There were 2 inconsistent shifts. Check your topology
> Done rmpbc
> 
> Constraining the starting coordinates (step -2)
> 
> ............
> 
> Initializing LINear Constraint Solver
>   number of constraints is 40
>   average number of constraints coupled to one constraint is 2.5
> 
>    Rel. Constraint Deviation:  Max    between atoms     RMS
>        Before LINCS         14.051325     37     38   2.221738
>         After LINCS         7.971895     38     39   1.863314
> 
> 
> Step -2, time -0.004 (ps)  LINCS WARNING
> relative constraint deviation after LINCS:
> max 7.971895 (between atoms 38 and 39) rms 1.863314
> bonds that rotated more than 30 degrees:
>  atom 1 atom 2  angle  previous, current, constraint length
>       1      2   88.9    0.1527   0.4141      0.1530
>      38      1   97.4    0.1510   1.0500      0.1530
>      33     34   90.8    0.1521   0.4259      0.1530
>      34     35   91.2    0.1444   0.4658      0.1430
>      34     37   99.2    0.1515   0.8675      0.1530
>      37     38   94.4    2.3029   0.5622      0.1530
>      38     39   88.1    0.1450   1.2830      0.1430
>      39     40   52.1    0.1018   0.1484      0.1000
> Constraint error in algorithm Lincs at step -2
> 
> Constraining the coordinates at t0-dt (step -1)
>    Rel. Constraint Deviation:  Max    between atoms     RMS
>        Before LINCS         7.959223     38     39   1.862687
>         After LINCS         5.711798     37     38   1.211940
> 
> 
> Step -1, time -0.002 (ps)  LINCS WARNING
> relative constraint deviation after LINCS:
> max 5.711798 (between atoms 37 and 38) rms 1.211940
> bonds that rotated more than 30 degrees:
>  atom 1 atom 2  angle  previous, current, constraint length
>       1      2  105.5    0.4141   0.2115      0.1530
>      38      1   96.1    1.0500   0.0735      0.1530
>       2      3   66.3    0.1245   0.1508      0.1430
>       3      4   44.3    0.1007   0.1377      0.1000
>       5      6   39.0    0.1533   0.1779      0.1530
>      33     34  100.5    0.4259   0.3628      0.1530
>      34     35   90.3    0.4658   0.5381      0.1430
>      34     37   99.1    0.8675   0.4135      0.1530
>      35     36   88.1    0.0396   0.2269      0.1000
>      37     38   98.9    0.5622   1.0269      0.1530
>      38     39   82.5    1.2830   0.1497      0.1430
>      39     40   85.2    0.1484   0.4389      0.1000
> Constraint error in algorithm Lincs at step -1
> 
> Started mdrun on node 0 Mon Nov 25 13:06:01 2002
> Initial temperature: 257962 K
> Grid: 4 x 4 x 4 cells
> Using buffers of length 1000 for innerloop vectorization.
> Full PBC calculation = TRUE
>            Step           Time         Lambda      Annealing
>               0        0.00000        0.00000        1.00000
> 
>    Rel. Constraint Deviation:  Max    between atoms     RMS
>        Before LINCS         16.617081     34     37   4.842547
>         After LINCS         7.988674     27     28   2.490661
> 
> 
> Step 0, time 0 (ps)  LINCS WARNING
> relative constraint deviation after LINCS:
> max 7.988674 (between atoms 27 and 28) rms 2.490661
> bonds that rotated more than 30 degrees:
>  atom 1 atom 2  angle  previous, current, constraint length
>       1      2   96.0    0.4141   0.8453      0.1530
>      38      1   91.9    1.0500   0.9421      0.1530
>       2      3   59.2    0.1245   0.1394      0.1430
>       3      4   38.5    0.1007   0.1243      0.1000
>      25     26   90.1    0.1532   0.3909      0.1530
>      26     27   90.0    0.1432   0.8420      0.1430
>      26     29   90.7    0.1534   0.3886      0.1530
>      27     28   90.0    0.1000   0.8989      0.1000
>      33     34   97.3    0.4259   0.7285      0.1530
>      34     35   87.9    0.4658   0.8409      0.1430
>      34     37   90.2    0.8675   0.9391      0.1530
>      37     38  107.8    0.5622   0.3559      0.1530
>      38     39   83.6    1.2220   0.4566      0.1430
>      39     40   89.8    0.1484   0.7116      0.1000
> Constraint error in algorithm Lincs at step 0
> 
> t = 0.000 ps: Water molecule starting at atom 74 can not be settled.
> Check for bad contacts and/or reduce the timestep.Wrote pdb files with previous and
> current coordin
> ates
>    Energies (kJ/mol)
>           Angle    Proper Dih.          LJ-14     Coulomb-14        LJ (SR)
>     2.52067e+03    7.33230e+01    2.90584e+01   -6.53393e+02    1.34327e+05
>    Coulomb (SR)      Potential    Kinetic En.   Total Energy    Temperature
>    -2.18829e+04    1.14414e+05           NaNQ           NaNQ           NaNQ
>  Pressure (bar)
>            NaNQ
> 
>            Step           Time         Lambda      Annealing
>               5        0.01000        0.00000        1.00000
> 
> xx[    0] before: (    NaNQ,    NaNQ,    NaNQ) After: (    NaNQ,    NaNQ,    NaNQ)
> xx[    1] before: (    NaNQ,    NaNQ,    NaNQ) After: (    NaNQ,    NaNQ,    NaNQ)
>  ..............
> Atoms 33-40 are at the end of the chain. 38 is periodically linked to 1.
> 
> I'm quite sure the topology is OK.
> (The same dynamics calculation on the chain 'not infinite' don't give problem).
> 
> Thanks for any suggestion.
> 
> Ester
> 
> 
> --
> Ester Chiessi
> Dipartimento di Scienze e Tecnologie Chimiche
> Universita' di Roma "Tor Vergata"
> Via della Ricerca Scientifica
> 00133 Roma (Italy)
> http://www.stc.uniroma2.it/cfmacro/cfmacroindex.htm
> e-mail: ester.chiessi at uniroma2.it
> Phone: 39*6*72594462
>        39*6*72594874
> Fax:39*6*72594328
> 
> 
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-- 
Groeten, David.
________________________________________________________________________
Dr. David van der Spoel, 	Biomedical center, Dept. of Biochemistry
Husargatan 3, Box 576,  	75123 Uppsala, Sweden
phone:	46 18 471 4205		fax: 46 18 511 755
spoel at xray.bmc.uu.se	spoel at gromacs.org   http://xray.bmc.uu.se/~spoel
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