[gmx-users] Fatal error: Atomtype 'OS' not found!

David van der Spoel spoel at xray.bmc.uu.se
Thu Oct 7 09:08:00 CEST 2004


On Thu, 2004-10-07 at 00:27, Yunfeng Hu wrote:
> However, everything is fine if cocaine.itp alone without protein is 
> used in the simulation. Here is what it looks like:

ffG43a1 has no atomtype OS. So this itp file can not work with that ff.
Check earlier discussions of prodrg and ffG43 on the list.

> 
>   [ moleculetype ]
>   ;name nrexcl
> COC      3
> ;
> ;
> ;       This file was generated by PRODRG version 040913.0519
> ;       PRODRG written/copyrighted by Daan van Aalten
> ;
> ;       Questions/comments to dava at davapc1.bioch.dundee.ac.uk
> ;
> ;       When using this software in a publication, cite:
> ;       A. W. Schuettelkopf and D. M. F. van Aalten (2004).
> ;       PRODRG - a tool for high-throughput crystallography
> ;       of protein-ligand complexes.
> ;       Acta Crystallogr. D60, 1355--1363.
> ;
> ;
>   [ atoms ]
>   ;  nr  type resnr resid  atom  cgnr charge
>       1   CH3     1 COC      C1     1    0.078
>       2    OS     1 COC      O5     1   -0.110
>       3     C     1 COC      C6     1    0.531
>       4     O     1 COC      O7     1   -0.499
>       5   CH1     1 COC      C8     2    0.127
>       6   CH1     1 COC     C10     2    0.127
>       7    NL     1 COC     N12     2   -0.300
>       8   CH3     1 COC     C14     2    0.046
>       9   CH2     1 COC     C18     3    0.000
>      10   CH2     1 COC     C21     3    0.000
>      11   CH1     1 COC     C24     4    0.000
>      12   CH2     1 COC     C26     5    0.100
>      13   CS1     1 COC     C29     5    0.258
>      14    OS     1 COC      O1     5   -0.141
>      15     C     1 COC      C2     5    0.418
>      16     O     1 COC      O3     5   -0.635
>      17    CB     1 COC      C4     6    0.015
>      18  CR61     1 COC      C5     6   -0.007
>      19  CR61     1 COC      C7     6   -0.008
>      20  CR61     1 COC      C9     7    0.000
>      21  CR61     1 COC     C11     7    0.000
>      22  CR61     1 COC     C13     7    0.000
>   [ bonds ]
>   ;ai  aj  fu    c0          c1
>     1   2   1 0.143    251040.0 0.143    251040.0 ;    C1   O5
>     2   3   1 0.136    376560.0 0.136    376560.0 ;    O5   C6
>     3   4   1 0.123    502080.0 0.123    502080.0 ;    C6   O7
>     3   5   1 0.153    334720.0 0.153    334720.0 ;    C6   C8
>     5   6   1 0.153    334720.0 0.153    334720.0 ;    C8  C10
>     5  13   1 0.153    334720.0 0.153    334720.0 ;    C8  C29
>     6   7   1 0.147    376560.0 0.147    376560.0 ;   C10  N12
>     6   9   1 0.153    334720.0 0.153    334720.0 ;   C10  C18
>     7   8   1 0.147    376560.0 0.147    376560.0 ;   N12  C14
>     7  11   1 0.147    376560.0 0.147    376560.0 ;   N12  C24
>     9  10   1 0.153    334720.0 0.153    334720.0 ;   C18  C21
>    10  11   1 0.153    334720.0 0.153    334720.0 ;   C21  C24
>    11  12   1 0.153    334720.0 0.153    334720.0 ;   C24  C26
>    12  13   1 0.153    251040.0 0.153    251040.0 ;   C26  C29
>    13  14   1 0.144    251040.0 0.144    251040.0 ;   C29   O1
>    14  15   1 0.136    376560.0 0.136    376560.0 ;    O1   C2
>    15  16   1 0.123    502080.0 0.123    502080.0 ;    C2   O3
>    15  17   1 0.153    334720.0 0.153    334720.0 ;    C2   C4
>    17  18   1 0.139    418400.0 0.139    418400.0 ;    C4   C5
>    17  22   1 0.139    418400.0 0.139    418400.0 ;    C4  C13
>    18  19   1 0.139    418400.0 0.139    418400.0 ;    C5   C7
>    19  20   1 0.139    418400.0 0.139    418400.0 ;    C7   C9
>    20  21   1 0.139    418400.0 0.139    418400.0 ;    C9  C11
>    21  22   1 0.139    418400.0 0.139    418400.0 ;   C11  C13
>   [ pairs ]
>   ;ai  aj  fu    c0          c1
>     1   4   1                   ;    C1   O7
>     1   5   1                   ;    C1   C8
>     2   6   1                   ;    O5  C10
>     2  13   1                   ;    O5  C29
>     3   7   1                   ;    C6  N12
>     3   9   1                   ;    C6  C18
>     3  12   1                   ;    C6  C26
>     3  14   1                   ;    C6   O1
>     4   6   1                   ;    O7  C10
>     4  13   1                   ;    O7  C29
>     5   8   1                   ;    C8  C14
>     5  10   1                   ;    C8  C21
>     5  11   1                   ;    C8  C24
>     5  15   1                   ;    C8   C2
>     6  12   1                   ;   C10  C26
>     6  14   1                   ;   C10   O1
>     7  13   1                   ;   N12  C29
>     8   9   1                   ;   C14  C18
>     8  10   1                   ;   C14  C21
>     8  12   1                   ;   C14  C26
>     9  12   1                   ;   C18  C26
>     9  13   1                   ;   C18  C29
>    10  13   1                   ;   C21  C29
>    11  14   1                   ;   C24   O1
>    12  15   1                   ;   C26   C2
>    13  16   1                   ;   C29   O3
>    13  17   1                   ;   C29   C4
>    14  18   1                   ;    O1   C5
>    14  22   1                   ;    O1  C13
>    15  19   1                   ;    C2   C7
>    15  21   1                   ;    C2  C11
>    16  18   1                   ;    O3   C5
>    16  22   1                   ;    O3  C13
>    17  20   1                   ;    C4   C9
>    18  21   1                   ;    C5  C11
>    19  22   1                   ;    C7  C13
>   [ angles ]
>   ;ai  aj  ak  fu    c0          c1
>     1   2   3   1 109.5       334.7 109.5       334.7 ;    C1   O5   C6
>     2   3   4   1 120.0       418.4 120.0       418.4 ;    O5   C6   O7
>     2   3   5   1 120.0       418.4 120.0       418.4 ;    O5   C6   C8
>     4   3   5   1 121.0       502.1 121.0       502.1 ;    O7   C6   C8
>     3   5   6   1 109.5       460.2 109.5       460.2 ;    C6   C8  C10
>     3   5  13   1 109.5       460.2 109.5       460.2 ;    C6   C8  C29
>     6   5  13   1 111.0       460.2 111.0       460.2 ;   C10   C8  C29
>     5   6   7   1 109.5       460.2 109.5       460.2 ;    C8  C10  N12
>     5   6   9   1 111.0       460.2 111.0       460.2 ;    C8  C10  C18
>     7   6   9   1 104.0       460.2 104.0       460.2 ;   N12  C10  C18
>     6   7   8   1 109.5       376.6 109.5       376.6 ;   C10  N12  C14
>     6   7  11   1 104.0       460.2 104.0       460.2 ;   C10  N12  C24
>     8   7  11   1 109.5       376.6 109.5       376.6 ;   C14  N12  C24
>     6   9  10   1 104.0       460.2 104.0       460.2 ;   C10  C18  C21
>     9  10  11   1 104.0       460.2 104.0       460.2 ;   C18  C21  C24
>     7  11  10   1 104.0       460.2 104.0       460.2 ;   N12  C24  C21
>     7  11  12   1 109.5       460.2 109.5       460.2 ;   N12  C24  C26
>    10  11  12   1 109.5       460.2 109.5       460.2 ;   C21  C24  C26
>    11  12  13   1 109.5       460.2 109.5       460.2 ;   C24  C26  C29
>     5  13  12   1 109.5       251.0 109.5       251.0 ;    C8  C29  C26
>     5  13  14   1 109.5       284.5 109.5       284.5 ;    C8  C29   O1
>    12  13  14   1 109.5       284.5 109.5       284.5 ;   C26  C29   O1
>    13  14  15   1 109.5       334.7 109.5       334.7 ;   C29   O1   C2
>    14  15  16   1 120.0       418.4 120.0       418.4 ;    O1   C2   O3
>    14  15  17   1 120.0       418.4 120.0       418.4 ;    O1   C2   C4
>    16  15  17   1 121.0       502.1 121.0       502.1 ;    O3   C2   C4
>    15  17  18   1 120.0       418.4 120.0       418.4 ;    C2   C4   C5
>    15  17  22   1 120.0       418.4 120.0       418.4 ;    C2   C4  C13
>    18  17  22   1 120.0       418.4 120.0       418.4 ;    C5   C4  C13
>    17  18  19   1 120.0       418.4 120.0       418.4 ;    C4   C5   C7
>    18  19  20   1 120.0       418.4 120.0       418.4 ;    C5   C7   C9
>    19  20  21   1 120.0       418.4 120.0       418.4 ;    C7   C9  C11
>    20  21  22   1 120.0       418.4 120.0       418.4 ;    C9  C11  C13
>    17  22  21   1 120.0       418.4 120.0       418.4 ;    C4  C13  C11
>   [ dihedrals ]
>   ;ai  aj  ak  al  fu    c0    c1 m  c0   c1 m
>     3   2   5   4   2   0.0 1673.6 0   0.0 1673.6 0 ; IDI    C6   O5   
> C8   O7
>    15  14  17  16   2   0.0 1673.6 0   0.0 1673.6 0 ; IDI    C2   O1   
> C4   O3
>    17  22  18  15   2   0.0 1673.6 0   0.0 1673.6 0 ; IDI    C4  C13   
> C5   C2
>     5   3   6  13   2  35.3  836.8 0  35.3  836.8 0 ; IDI    C8   C6  
> C10  C29
>     6   5   7   9   2  35.3  836.8 0  35.3  836.8 0 ; IDI   C10   C8  
> N12  C18
>     7   6  11   8   2  35.3  836.8 0  35.3  836.8 0 ; IDI   N12  C10  
> C24  C14
>    11   7  12  10   2  35.3  836.8 0  35.3  836.8 0 ; IDI   C24  N12  
> C26  C21
>    13   5  12  14   2  35.3  836.8 0  35.3  836.8 0 ; IDI   C29   C8  
> C26   O1
>    17  18  19  20   2   0.0 1673.6 0   0.0 1673.6 0 ; IDI    C4   C5   
> C7   C9
>    18  19  20  21   2   0.0 1673.6 0   0.0 1673.6 0 ; IDI    C5   C7   
> C9  C11
>    19  20  21  22   2   0.0 1673.6 0   0.0 1673.6 0 ; IDI    C7   C9  
> C11  C13
>    20  21  22  17   2   0.0 1673.6 0   0.0 1673.6 0 ; IDI    C9  C11  
> C13   C4
>    21  22  17  18   2   0.0 1673.6 0   0.0 1673.6 0 ; IDI   C11  C13   
> C4   C5
>    22  17  18  19   2   0.0 1673.6 0   0.0 1673.6 0 ; IDI   C13   C4   
> C5   C7
>     1   2   3   5   1 180.0   16.7 2 180.0   16.7 2 ; DI     C1   O5   
> C6   C8
>    13   5   3   2   1   0.0    0.4 6   0.0    0.4 6 ; DI    C29   C8   
> C6   O5
>     9   6   5   3   1   0.0    5.9 3   0.0    5.9 3 ; DI    C18  C10   
> C8   C6
>     3   5  13  14   1   0.0    5.9 3   0.0    5.9 3 ; DI     C6   C8  
> C29   O1
>     5   6   7  11   1   0.0    3.8 3   0.0    3.8 3 ; DI     C8  C10  
> N12  C24
>    10   9   6   5   1   0.0    5.9 3   0.0    5.9 3 ; DI    C21  C18  
> C10   C8
>    12  11   7   6   1   0.0    3.8 3   0.0    3.8 3 ; DI    C26  C24  
> N12  C10
>    11  10   9   6   1   0.0    5.9 3   0.0    5.9 3 ; DI    C24  C21  
> C18  C10
>     9  10  11  12   1   0.0    5.9 3   0.0    5.9 3 ; DI    C18  C21  
> C24  C26
>    13  12  11   7   1   0.0    5.9 3   0.0    5.9 3 ; DI    C29  C26  
> C24  N12
>    14  13  12  11   1   0.0    5.9 3   0.0    5.9 3 ; DI     O1  C29  
> C26  C24
>     5  13  14  15   1   0.0    3.8 3   0.0    3.8 3 ; DI     C8  C29   
> O1   C2
>    13  14  15  17   1 180.0   16.7 2 180.0   16.7 2 ; DI    C29   O1   
> C2   C4
>    22  17  15  14   1 180.0    5.9 2 180.0    5.9 2 ; DI    C13   C4   
> C2   O1
> 
> 
> On Wed, 2004-10-06 at 18:49, Yunfeng Hu wrote:
> > In fact that is what I did. Here is what my topology file looks like:
> > ;
> > ;       File '7a1.top' was generated
> > ;       By user: yunfenghu (501)
> > ;       On host: Yunfeng-Hus-Computer.local
> > ;       At date: Thu Sep 30 17:46:23 2004
> > ;
> > ;       This is your topology file
> > ;       "Uh-oh .... Right Again" (Laurie Anderson)
> > ;
> > ; Include forcefield parameters
> > #include "ffG43a1.itp"
> > #include "cocaine.itp"
> 
> Most likely your file cocaine.tip also includes a forcefield statement
> and/or atomtypes and/or charges in cocaine.itp have to be adapted to
> ffG43a1 (which are different than ffgmx).
> 
> 
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-- 
David.
________________________________________________________________________
David van der Spoel, PhD, Assoc. Prof., Molecular Biophysics group,
Dept. of Cell and Molecular Biology, Uppsala University.
Husargatan 3, Box 596,  	75124 Uppsala, Sweden
phone:	46 18 471 4205		fax: 46 18 511 755
spoel at xray.bmc.uu.se	spoel at gromacs.org   http://xray.bmc.uu.se/~spoel
++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++





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