Dear gmx-users, Could you please tell me what is the mean of option s in file 'mdrun_make_hole.tar.gz' for instance 'grompp -f run.mdp -s insert.tpr -c outbilayer.pdb -r outbilayer.pdb -p ...'? If i want to run program 'mdrun_make_hole', where can i get a guide as a beginner in Gromacs except 'Putting Proteins into Bilayers (v 3.1)'? Thank you! Weidong