[gmx-users] Re: Re: g_chi -omega

Dongsheng Zhang dong at pampas.chem.purdue.edu
Tue Nov 29 16:24:38 CET 2005


Dear David,

Thank you very much for your reply. When I use vmd to visualize this
peptide (PPII-PRO.PDB), I think it is trans conformation because two
C-alphas connected by an amide bond are at both sides of the amide bond.
I am confused why you think it is cis conformation. Please give me more
details. I got this PDB file from:
http://www.cryst.bbk.ac.uk/pps97/assignments/projects/szabo/proline.htm

>From this website, you can find that the author also thinks this peptide
is trans conformation.
> 
> Message: 2
> Date: 29 Nov 2005 00:47:41 -0500
> From: Dongsheng Zhang <dong at pampas.chem.purdue.edu>
> Subject: [gmx-users] g_chi -omega
> To: gmx-users at gromacs.org
> Message-ID: <1133243260.32559.56.camel at pampas.chem.purdue.edu>
> Content-Type: text/plain
> 
> Hi,
> 
> I have checked the mailing archive, It seems no one complained about the
> calculation of omega angle. I have a PDB file for polyproline with trans
> conformation. But when I use 
> 
> g_chi -s PPII-PRO.PDB -f PPII-PRO.PDB -omega
> 
> to calculate the omega angle. I got zero. To my understanding, the omega
> should be 180 for trans conformation. Could anyone tell me where I made
> a mistake?
> 
> 
> 
> PPII-PRO.PDB:
> 
>  ATOM      1  N   PRO     2       3.553   1.514  -1.245  1.00 
> 0.00              
> ATOM      2  CA  PRO     2       4.313   2.450  -2.183  1.00 
> 0.00              
> ATOM      3  C   PRO     2       4.115   2.148  -3.667  1.00 
> 0.00              
> ATOM      4  O   PRO     2       3.990   0.946  -4.012  1.00 
> 0.00              
> ATOM      5  CB  PRO     2       5.789   2.270  -1.860  1.00 
> 0.00              
> ATOM      6  CG  PRO     2       5.822   0.779  -1.484  1.00 
> 0.00              
> ATOM      7  CD  PRO     2       4.548   0.586  -0.655  1.00 
> 0.00              
> ATOM      8  H   PRO     2       2.857   1.014  -1.816  1.00 
> 0.00              
> ATOM      9  HA  PRO     2       3.992   3.469  -2.028  1.00 
> 0.00              
> ATOM     10 1HB  PRO     2       6.384   2.410  -2.780  1.00 
> 0.00              
> ATOM     11 2HB  PRO     2       6.044   2.871  -0.979  1.00 
> 0.00              
> ATOM     12 1HG  PRO     2       5.602   0.098  -2.322  1.00 
> 0.00              
> ATOM     13 2HG  PRO     2       6.750   0.622  -0.918  1.00 
> 0.00              
> ATOM     14 1HD  PRO     2       4.190  -0.452  -0.756  1.00 
> 0.00              
> ATOM     15 2HD  PRO     2       4.743   0.888   0.386  1.00 
> 0.00              
> ATOM     16  N   PRO     3       4.077   3.120  -4.560  1.00 
> 0.00              
> ATOM     17  CA  PRO     3       3.887   2.960  -6.067  1.00 
> 0.00              
> ATOM     18  C   PRO     3       5.118   2.438  -6.804  1.00 
> 0.00              
> ATOM     19  O   PRO     3       6.248   2.799  -6.390  1.00 
> 0.00              
> ATOM     20  CB  PRO     3       3.570   4.348  -6.605  1.00 
> 0.00              
> ATOM     21  CG  PRO     3       4.413   5.223  -5.661  1.00 
> 0.00              
> ATOM     22  CD  PRO     3       4.211   4.571  -4.289  1.00 
> 0.00              
> ATOM     23  HA  PRO     3       3.086   2.263  -6.266  1.00 
> 0.00              
> ATOM     24 1HB  PRO     3       3.978   4.445  -7.626  1.00 
> 0.00              
> ATOM     25 2HB  PRO     3       2.507   4.566  -6.447  1.00 
> 0.00              
> ATOM     26 1HG  PRO     3       5.501   5.086  -5.772  1.00 
> 0.00              
> ATOM     27 2HG  PRO     3       4.007   6.240  -5.734  1.00 
> 0.00              
> ATOM     28 1HD  PRO     3       5.097   4.749  -3.657  1.00 
> 0.00              
> ATOM     29 2HD  PRO     3       3.272   4.939  -3.847  1.00 
> 0.00              
> ATOM     30  N   PRO     4       4.998   1.634  -7.843  1.00 
> 0.00              
> ATOM     31  CA  PRO     4       6.139   1.041  -8.668  1.00 
> 0.00              
> ATOM     32  C   PRO     4       6.812   2.033  -9.613  1.00 
> 0.00              
> ATOM     33  O   PRO     4       6.094   2.913 -10.152  1.00 
> 0.00              
> ATOM     34  CB  PRO     4       5.524  -0.067  -9.510  1.00 
> 0.00              
> ATOM     35  CG  PRO     4       4.125   0.514  -9.775  1.00 
> 0.00              
> ATOM     36  CD  PRO     4       3.731   1.134  -8.431  1.00 
> 0.00              
> ATOM     37  HA  PRO     4       6.911   0.664  -8.013  1.00 
> 0.00              
> ATOM     38 1HB  PRO     4       6.061  -0.134 -10.473  1.00 
> 0.00              
> ATOM     39 2HB  PRO     4       5.430  -0.976  -8.903  1.00 
> 0.00              
> ATOM     40 1HG  PRO     4       4.125   1.419 -10.403  1.00 
> 0.00              
> ATOM     41 2HG  PRO     4       3.491  -0.329 -10.078  1.00 
> 0.00              
> ATOM     42 1HD  PRO     4       3.043   1.980  -8.597  1.00 
> 0.00              
> ATOM     43 2HD  PRO     4       3.319   0.351  -7.776  1.00 
> 0.00              
> ATOM     44  N   PRO     5       8.108   1.969  -9.858  1.00 
> 0.00              
> ATOM     45  CA  PRO     5       8.905   2.893 -10.776  1.00 
> 0.00              
> ATOM     46  C   PRO     5       8.691   2.634 -12.266  1.00 
> 0.00              
> ATOM     47  O   PRO     5       8.515   1.446 -12.637  1.00 
> 0.00              
> ATOM     48  CB  PRO     5      10.373   2.643 -10.461  1.00 
> 0.00              
> ATOM     49  CG  PRO     5      10.343   1.144 -10.120  1.00 
> 0.00              
> ATOM     50  CD  PRO     5       9.064   0.987  -9.291  1.00 
> 0.00              
> ATOM     51  HA  PRO     5       8.628   3.921 -10.597  1.00 
> 0.00              
> ATOM     52 1HB  PRO     5      10.971   2.779 -11.379  1.00 
> 0.00              
> ATOM     53 2HB  PRO     5      10.655   3.213  -9.568  1.00 
> 0.00              
> ATOM     54 1HG  PRO     5      10.092   0.492 -10.972  1.00 
> 0.00              
> ATOM     55 2HG  PRO     5      11.264   0.935  -9.559  1.00 
> 0.00              
> ATOM     56 1HD  PRO     5       8.661  -0.032  -9.414  1.00 
> 0.00              
> ATOM     57 2HD  PRO     5       9.273   1.257  -8.245  1.00 
> 0.00              
> 
> -- 
> Dongsheng Zhang <dong at pampas.chem.purdue.edu>
> 
> 
> ------------------------------

> 
> Message: 5
> Date: Tue, 29 Nov 2005 09:03:34 +0100
> From: David van der Spoel <spoel at xray.bmc.uu.se>
> Subject: Re: [gmx-users] g_chi -omega
> To: Discussion list for GROMACS users <gmx-users at gromacs.org>
> Message-ID: <438C0B56.4020606 at xray.bmc.uu.se>
> Content-Type: text/plain; charset=ISO-8859-1; format=flowed
> 
> Dongsheng Zhang wrote:
> > Hi,
> > 
> > I have checked the mailing archive, It seems no one complained about the
> > calculation of omega angle. I have a PDB file for polyproline with trans
> > conformation. But when I use 
> > 
> > g_chi -s PPII-PRO.PDB -f PPII-PRO.PDB -omega
> > 
> > to calculate the omega angle. I got zero. To my understanding, the omega
> > should be 180 for trans conformation. Could anyone tell me where I made
> > a mistake?
> > 
> 
> It seems that your angles are indeed Cis. The definition of omega is 
> Ca-N-C-O which is indeed 0 degrees in the conformation you sent to the 
> list. Where did you get the coordinates from?
> 
> 
> -- 
> David.
> ________________________________________________________________________
> David van der Spoel, PhD, Assoc. Prof., Molecular Biophysics group,
> Dept. of Cell and Molecular Biology, Uppsala University.
> Husargatan 3, Box 596,  	75124 Uppsala, Sweden
> phone:	46 18 471 4205		fax: 46 18 511 755
> spoel at xray.bmc.uu.se	spoel at gromacs.org   http://xray.bmc.uu.se/~spoel
> ++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++
> 
> 
> ------------------------------
> 

-- 
Dongsheng Zhang <dong at pampas.chem.purdue.edu>



More information about the gromacs.org_gmx-users mailing list