[gmx-users] problems generating hessian matrix

David van der Spoel spoel at xray.bmc.uu.se
Tue Aug 8 07:52:27 CEST 2006


Nima S Panahi wrote:
> PLEASE HELP ASAP I need this to work. Thanks in advance
> I run
> 
> /usr/local/gromacs/bin/grompp_d -f argon.mdp -c argon.gro -p topol.top  
> -o file.tpr
> 
> followed by
> 
> /usr/local/gromacs/bin/mdrun_d -s file.tpr -o file.trr -c mdout.gro -e  
> ener.edr -g md.log -mtx nm.mtx
> 
> but there is not nm.mtx created
> 
> 
> my arong.mdp looks like:
> ; VARIOUS PREPROCESSING OPTIONS
> title                    =
> cpp                      = /lib/cpp
> include                  =
> define                   =
> 
> ; RUN CONTROL PARAMETERS
> integrator               = md

integrator = nm

> ; Start time and timestep in ps
> tinit                    = 0
> dt                       = 0.002
> nsteps                   = 25000
> ; For exact run continuation or redoing part of a run
> init_step                = 0
> ; mode for center of mass motion removal
> comm-mode                = Linear
> ; number of steps for center of mass motion removal
> nstcomm                  = 1
> ; group(s) for center of mass motion removal
> comm-grps                =
> 
> ; LANGEVIN DYNAMICS OPTIONS
> ; Temperature, friction coefficient (amu/ps) and random seed
> bd-temp                  = 120
> bd-fric                  = 0
> ld-seed                  = 1993
> 
> ; ENERGY MINIMIZATION OPTIONS
> ; Force tolerance and initial step-size
> emtol                    = 100
> emstep                   = 0.01
> ; Max number of iterations in relax_shells
> niter                    = 20
> ; Step size (1/ps^2) for minimization of flexible constraints
> fcstep                   = 0
> ; Frequency of steepest descents steps when doing CG
> nstcgsteep               = 1000
> nbfgscorr                = 10
> 
> ; OUTPUT CONTROL OPTIONS
> ; Output frequency for coords (x), velocities (v) and forces (f)
> nstxout                  = 10000
> nstvout                  = 10000
> nstfout                  = 0
> ; Checkpointing helps you continue after crashes
> nstcheckpoint            = 1000
> ; Output frequency for energies to log file and energy file
> nstlog                   = 100
> nstenergy                = 100
> ; Output frequency and precision for xtc file
> nstxtcout                = 100
> xtc-precision            = 1000
> ; This selects the subset of atoms for the xtc file. You can
> ; select multiple groups. By default all atoms will be written.
> xtc-grps                 =
> ; Selection of energy groups
> energygrps               =
> 
> ; NEIGHBORSEARCHING PARAMETERS
> ; nblist update frequency
> nstlist                  = 1
> ; ns algorithm (simple or grid)
> ns-type                  = grid
> ; Periodic boundary conditions: xyz (default), no (vacuum)
> ; or full (infinite systems only)
> pbc                      = xyz
> ; nblist cut-off
> rlist                    = 2.5
> domain-decomposition     = no
> 
> ; OPTIONS FOR ELECTROSTATICS AND VDW
> ; Method for doing electrostatics
> coulombtype              = Cut-off
> rcoulomb-switch          = 0
> rcoulomb                 = 2.5
> ; Dielectric constant (DC) for cut-off or DC of reaction field
> epsilon-r                = 1
> ; Method for doing Van der Waals
> vdw-type                 = Cut-off
> ; cut-off lengths
> rvdw-switch              = 0
> rvdw                     = 2.5
> ; Apply long range dispersion corrections for Energy and Pressure
> DispCorr                 = EnerPres
> ; Extension of the potential lookup tables beyond the cut-off
> table-extension          = 1
> ; Spacing for the PME/PPPM FFT grid
> fourierspacing           = 0.12
> ; FFT grid size, when a value is 0 fourierspacing will be used
> fourier_nx               = 0
> fourier_ny               = 0
> fourier_nz               = 0
> ; EWALD/PME/PPPM parameters
> pme_order                = 4
> ewald_rtol               = 1e-05
> ewald_geometry           = 3d
> epsilon_surface          = 0
> optimize_fft             = no
> 
> ; GENERALIZED BORN ELECTROSTATICS
> ; Algorithm for calculating Born radii
> gb_algorithm             = Still
> ; Frequency of calculating the Born radii inside rlist
> nstgbradii               = 1
> ; Cutoff for Born radii calculation; the contribution from atoms
> ; between rlist and rgbradii is updated every nstlist steps
> rgbradii                 = 2
> ; Salt concentration in M for Generalized Born models
> gb_saltconc              = 0
> 
> ; IMPLICIT SOLVENT (for use with Generalized Born electrostatics)
> implicit_solvent         = No
> 
> ; OPTIONS FOR WEAK COUPLING ALGORITHMS
> ; Temperature coupling
> tcoupl                   = No
> ; Groups to couple separately
> tc-grps                  = system
> ; Time constant (ps) and reference temperature (K)
> tau-t                    = 0.1
> ref-t                    = 120
> ; Pressure coupling
> Pcoupl                   = No
> Pcoupltype               = Isotropic
> ; Time constant (ps), compressibility (1/bar) and reference P (bar)
> tau-p                    = 1
> compressibility          = 5e-5
> ref-p                    = 1
> ; Random seed for Andersen thermostat
> andersen_seed            = 815131
> 
> ; SIMULATED ANNEALING
> ; Type of annealing for each temperature group (no/single/periodic)
> annealing                =
> ; Number of time points to use for specifying annealing in each group
> annealing_npoints        =
> ; List of times at the annealing points for each group
> annealing_time           =
> ; Temp. at each annealing point, for each group.
> annealing_temp           =
> 
> ; GENERATE VELOCITIES FOR STARTUP RUN
> gen-vel                  = no
> gen-temp                 = 120
> gen-seed                 = 173529
> 
> 
> my argon.go looks like:
> Argon
>   13
>        1AR   AR    1  -0.033   0.081   0.257  0.1866 -0.2544  0.5213
>        2AR   AR    2  -0.034  -0.140  -0.353  0.3855 -0.4920  0.8269
>        3AR   AR    3   0.355  -0.067  -0.367 -0.0668  0.4193  0.6096
>        4AR   AR    4   0.311  -0.125   0.176  0.2093 -0.6313  0.9828
>        5AR   AR    5  -0.042   0.366   0.008 -0.3232 -0.4550 -0.9181
>        6AR   AR    6  -0.308  -0.321  -0.171  0.7523  0.3857  0.3527
>        7AR   AR    7   0.501   0.124  -0.072  0.8134 -0.6625  0.8499
>        8AR   AR    8   0.570  -0.241  -0.088  0.3273  0.9660 -0.6965
>        9AR   AR    9   0.282   0.265   0.192 -0.8447  0.3001  0.6661
>       10AR   AR   10  -0.050  -0.244   0.089 -0.0174  0.2349  0.8296
>       11AR   AR   11   0.134   0.051  -0.088 -0.0855  0.6894 -0.7369
>       12AR   AR   12   0.215  -0.331  -0.145 -0.3998 -0.9677  0.2980
>       13AR   AR   13  -0.236   0.042  -0.072  0.2268 -0.5540  0.4119
>    6.65637   6.65637   6.65637
> 
> my topol.top looks like:
> 
> [ defaults ]
> ; nbfunc        comb-rule
> 1               3
> 
> [ atomtypes ]
> ; full atom descriptions are available in ffoplsaa.atp
> ; name  bond_type    mass    charge   ptype     sigma      epsilon
> AR      AR      39.94800        0       A       0.34     .9974
> 
> [ molecule_type ]
> Argon   1
> 
> [ atoms ]
> ;   nr   type  resnr residue  atom   cgnr     charge       mass
>      1     AR      1     AR     AR      1     0
> 
> 
> [ system ]
> ; Name
> Argon
> 
> [ molecules ]
> ; Compound        #mols
> Argon           13
> 
> 


-- 
David.
________________________________________________________________________
David van der Spoel, PhD, Assoc. Prof., Molecular Biophysics group,
Dept. of Cell and Molecular Biology, Uppsala University.
Husargatan 3, Box 596,  	75124 Uppsala, Sweden
phone:	46 18 471 4205		fax: 46 18 511 755
spoel at xray.bmc.uu.se	spoel at gromacs.org   http://folding.bmc.uu.se
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