[gmx-users] What is this??

[Marc Charendoff]

I've been trying to follow the Enzyme-drug tutorial by
Kerrigan when I ran into the following:

My input as per tutorial. . . . 

2:/gromacs Marc$ genbox -cp trp2.pdb -cs spc216.gro -o
trp_b4ion.pdb -p trp.top


Here is the output . . . .

Opening library file
/gromacs/share/gromacs/top/aminoacids.dat
Opening library file
/gromacs/share/gromacs/top/atommass.dat
Opening library file
/gromacs/share/gromacs/top/vdwradii.dat
Opening library file
/gromacs/share/gromacs/top/dgsolv.dat
#Entries in atommass.dat: 82 vdwradii.dat: 26
dgsolv.dat: 7
Reading solute configuration
S  C  A  M  O  R  G
Containing 2133 atoms in 251 residues
Initialising van der waals distances...
Reading solvent configuration
"216H2O,WATJP01,SPC216,SPC-MODEL,300K,BOX(M)=1.86206NM,WFVG,MAR.
1984"
solvent configuration contains 648 atoms in 216
residues

Initialising van der waals distances...
Will generate new solvent configuration of 68x64x55
boxes
genbox(293) malloc: *** vm_allocate(size=1909243904)
failed (error code=3)
genbox(293) malloc: *** error: can't allocate region
genbox(293) malloc: *** set a breakpoint in
szone_error to debug
-------------------------------------------------------
Program genbox, VERSION 3.3
Source code file: smalloc.c, line: 137

Fatal error:
realloc for atoms_solvt->atom (1909243904 bytes, file
gmx_genbox.c, line 399, atoms_solvt->atom=0x0x 
390000)
-------------------------------------------------------

"As Always Your Logic Is Impeccable" (Tuvok)
: Cannot allocate memory


Guidance appreciated.

Marc