[gmx-users] determining of Kn and Posn in Umbrella sampling

[Mark Abraham]

Farzad Molani wrote:
> Hi dear
> I want to compute PMF between two amine molecoules by umbrella sampling 
> but I do'nt know Kn and Posn in umbrella samplig how are determining.
> if you are having points please help me.

It sounds like you need some textbook-type material. Try googling 
"umbrella sampling" for a start.

Mark