[gmx-users] Proline on OPLSSaa

Mark Abraham Mark.Abraham at anu.edu.au
Mon Feb 11 00:02:37 CET 2008


Mauro Puppett wrote:
> 
> Hi all,
> I'm trying to run a simulation of a proline in water tip5p with OPLSaa ff.

<snip>

> and it works fine till i run grompp which says:
> 
> ERROR 0 [file "proline.top", line 182]:
>   No default Ryckaert-Bell. types
> ERROR 0 [file "proline.top", line 191]:
>   No default Ryckaert-Bell. types
> ERROR 0 [file "proline.top", line 193]:
>   No default Ryckaert-Bell. types
> ERROR 0 [file "proline.top", line 201]:
>   No default Ryckaert-Bell. types

Well, what's on these lines? Probably you're mis-naming some atom types, 
but you'll need to do your own leg-work finding out which ones!

Mark

> This is my .top file:
> 
> ;	This is your topology file
> ;	%E
> ;
> ; Include forcefield parameters
> #include "ffoplsaa.itp"
> 
> ; Include water topology
> #include "tip5p.itp"
> 
> #ifdef POSRES_WATER
> ; Position restraint for each water oxygen
> [ position_restraints ]
> ;  i funct       fcx        fcy        fcz
>    1    1       1000       1000       1000
> #endif
> 
> 
> [ moleculetype ]
> ; Name            nrexcl
> Protein             3
> 
> [ atoms ]
> ;   nr       type  resnr residue  atom   cgnr     charge       mass  typeB    chargeB      massB
>      1   opls_239      1    APR      N      1  -0.776797    14.0067   ; qtot -0.7768
>      2   opls_246      1    APR     CA      2  -0.158578     12.011   ; qtot -0.9354
>      3   opls_058      1    APR     C1      3    0.95425     12.011   ; qtot 0.01887
>      4   opls_062      1    APR    OS1      4   -0.71999    15.9994   ; qtot -0.7011
>      5   opls_235      1    APR     C2      5   0.808979     12.011   ; qtot 0.1079
>      6   opls_059      1    APR     OS      6  -0.616492    15.9994   ; qtot -0.5086
>      7   opls_245      1    APR     CD      7  -0.150278     12.011   ; qtot -0.6589
>      8   opls_136      1    APR     CB      8  -0.404838     12.011   ; qtot -1.064
>      9   opls_140      1    APR    HB1      9    0.24345      1.008   ; qtot -0.8203
>     10   opls_136      1    APR     CG     10  -0.450709     12.011   ; qtot -1.271
>     11   opls_140      1    APR    HB2     11   0.226125      1.008   ; qtot -1.045
>     12   opls_140      1    APR    HG1     12   0.223126      1.008   ; qtot -0.8218
>     13   opls_140      1    APR    HG2     13   0.242534      1.008   ; qtot -0.5792
>     14   opls_140      1    APR    HD1     14    0.23943      1.008   ; qtot -0.3398
>     15   opls_140      1    APR    HD2     15   0.239331      1.008   ; qtot -0.1005
>     16   opls_140      1    APR     HA     16   0.262623      1.008   ; qtot 0.1622
>     17   opls_468      1    APR     CE     17  -0.252649     12.011   ; qtot -0.09048
>     18   opls_469      1    APR    HE1     18   0.216104      1.008   ; qtot 0.1256
>     19   opls_469      1    APR    HE2     19   0.214466      1.008   ; qtot 0.3401
>     20   opls_469      1    APR    HE3     20   0.212312      1.008   ; qtot 0.5524
>     21   opls_236      1    APR     OB     21  -0.606932    15.9994   ; qtot -0.05453
>     22   opls_135      1    APR     CF     22  -0.687405     12.011   ; qtot -0.7419
>     23   opls_140      1    APR    HF1     23   0.262125      1.008   ; qtot -0.4798
>     24   opls_140      1    APR    HF2     24   0.224449      1.008   ; qtot -0.2554
>     25   opls_140      1    APR    HF3     25   0.255303      1.008   ; qtot -6.101e-05
> 
> [ bonds ]
> ;  ai    aj funct            c0            c1            c2            c3
>     1     2     1 
>     1     5     1 
>     1     7     1 
>     2     3     1 
>     2     8     1 
>     3     4     1 
>     3     6     1 
>     4    17     1 
>     5    21     1 
>     5    22     1 
>     7    10     1 
>     7    14     1 
>     7    15     1 
>     8     9     1 
>     8    10     1 
>     8    11     1 
>    10    12     1 
>    10    13     1 
>    17    18     1 
>    17    20     1 
>    22    23     1 
>    22    24     1 
>    22    25     1 
> 
> [ pairs ]
> ;  ai    aj funct            c0            c1            c2            c3
>     1     4     1 
>     1     6     1 
>     1     9     1 
>     1    11     1 
>     1    12     1 
>     1    13     1 
>     1    23     1 
>     1    24     1 
>     1    25     1 
>     2    12     1 
>     2    13     1 
>     2    14     1 
>     2    15     1 
>     2    17     1 
>     2    21     1 
>     2    22     1 
>     3     5     1 
>     3     7     1 
>     3     9     1 
>     3    10     1 
>     3    11     1 
>     3    18     1 
>     3    20     1 
>     4     8     1 
>     5     8     1 
>     5    10     1 
>     5    14     1 
>     5    15     1 
>     6     8     1 
>     6    17     1 
>     7     9     1 
>     7    11     1 
>     7    21     1 
>     7    22     1 
>     8    14     1 
>     8    15     1 
>     9    12     1 
>     9    13     1 
>    11    12     1 
>    11    13     1 
>    12    14     1 
>    12    15     1 
>    13    14     1 
>    13    15     1 
>    21    23     1 
>    21    24     1 
>    21    25     1 
> 
> [ angles ]
> ;  ai    aj    ak funct            c0            c1            c2            c3
>     2     1     5     1 
>     2     1     7     1 
>     5     1     7     1 
>     1     2     3     1 
>     1     2     8     1 
>     3     2     8     1 
>     2     3     4     1 
>     2     3     6     1 
>     4     3     6     1 
>     3     4    17     1 
>     1     5    21     1 
>     1     5    22     1 
>    21     5    22     1 
>     1     7    10     1 
>     1     7    14     1 
>     1     7    15     1 
>    10     7    14     1 
>    10     7    15     1 
>    14     7    15     1 
>     2     8     9     1 
>     2     8    10     1 
>     2     8    11     1 
>     9     8    10     1 
>     9     8    11     1 
>    10     8    11     1 
>     7    10     8     1 
>     7    10    12     1 
>     7    10    13     1 
>     8    10    12     1 
>     8    10    13     1 
>    12    10    13     1 
>     4    17    18     1 
>     4    17    20     1 
>    18    17    20     1 
>     5    22    23     1 
>     5    22    24     1 
>     5    22    25     1 
>    23    22    24     1 
>    23    22    25     1 
>    24    22    25     1 
> 
> [ dihedrals ]
> ;  ai    aj    ak    al funct            c0            c1            c2            c3            c4            c5
>     5     1     2     3     3 
>     5     1     2     8     3 
>     7     1     2     3     3 
>     7     1     2     8     3 
>     2     1     5    21     3 
>     2     1     5    22     3 
>     7     1     5    21     3 
>     7     1     5    22     3 
>     2     1     7    10     3 
>     2     1     7    14     3 
>     2     1     7    15     3 
>     5     1     7    10     3 
>     5     1     7    14     3 
>     5     1     7    15     3 
>     1     2     3     4     3 
>     1     2     3     6     3 
>     8     2     3     4     3 
>     8     2     3     6     3 
>     1     2     8     9     3 
>     1     2     8    10     3 
>     1     2     8    11     3 
>     3     2     8     9     3 
>     3     2     8    10     3 
>     3     2     8    11     3 
>     2     3     4    17     3 
>     6     3     4    17     3 
>     3     4    17    18     3 
>     3     4    17    20     3 
>     1     5    22    23     3 
>     1     5    22    24     3 
>     1     5    22    25     3 
>    21     5    22    23     3 
>    21     5    22    24     3 
>    21     5    22    25     3 
>     1     7    10     8     3 
>     1     7    10    12     3 
>     1     7    10    13     3 
>    14     7    10     8     3 
>    14     7    10    12     3 
>    14     7    10    13     3 
>    15     7    10     8     3 
>    15     7    10    12     3 
>    15     7    10    13     3 
>     2     8    10     7     3 
>     2     8    10    12     3 
>     2     8    10    13     3 
>     9     8    10     7     3 
>     9     8    10    12     3 
>     9     8    10    13     3 
>    11     8    10     7     3 
>    11     8    10    12     3 
>    11     8    10    13     3 
> 
> ; Include Position restraint file
> #ifdef POSRES
> #include "posre.itp"
> #endif
> 
> ; Include generic topology for ions
> #include "ions.itp"
> 
> [ system ]
> ; Name
> %E in water
> 
> [ molecules ]
> ; Compound        #mols
> Protein             1
> SOL              2390
> 
> Can somebody pelase tell what I'm doing wrong?
> Thanks in advance
> Mauro Puppett
> 
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