[gmx-users] Re: Strange PDO output during umbrella sampling

Ilya Chorny ichorny at gmail.com
Sat Feb 23 22:57:53 CET 2008


Scratch my post. I need to learn to read the manual more closely. I thought
the PDO output was the distance and not the deviation from the restrained
position.

Thanks,

Ilya


On Sat, Feb 23, 2008 at 1:04 PM, Ilya Chorny <ichorny at gmail.com> wrote:

> Hi All,
>
> I am trying to do umbrella sampling and I am getting very strange PDO
> output. The PDO out put does not correspond to the distances between groups.
> Below is my pdo output my mdp and ppa info and log file info showing the
> distances. I compared the values with output from g_dist just to verify. I
> also tried these run using 3.3.1(windows) and 3.3.2(unix) and got the same
> results. Any ideas?
>
> Thanks,
>
> Ilya
>
> LOG:
> REFERENCE TYPE: center of mass of reference group
> Looking for group AMM1: found group AMM1: 5 elements. First: 110535
> Looking for group AMM2: found group AMM2: 5 elements. First: 110540
> Looking for group AMM3: found group AMM3: 5 elements. First: 110545
> Looking for group Backbone: found group Backbone: 3159 elements. First: 1
> Initializing pull groups. Inv. mass of group 1: 0.055436
> Initial coordinates center of mass:    4.051    5.855    5.049
> Initializing pull groups. Inv. mass of group 2: 0.055436
> Initial coordinates center of mass:    6.770    5.254    5.102
> Initializing pull groups. Inv. mass of group 3: 0.055436
> Initial coordinates center of mass:    5.992    8.042    5.153
> Initializing reference group. Inv. mass: 0.000025
> Initial coordinates center of mass:    5.768    6.669    5.128
> Initial distance of group 1:    0.079
> Initial distance of group 2:    0.026
> Initial distance of group 3:    0.025
>
> PDO:
>
> # UMBRELLA    3.0
> # Component selection: 0 0 1
> # nSkip 10
> # Ref. Group 'Backbone'
> # Nr. of pull groups 3
> # Group 1 'AMM1'  Umb. Pos. 1.000000  Umb. Cons. 3000.000000
> # Group 2 'AMM2'  Umb. Pos. 1.000000  Umb. Cons. 3000.000000
> # Group 3 'AMM3'  Umb. Pos. 1.000000  Umb. Cons. 3000.000000
> #####
> 0.000000    -1.079179    -1.025911    -0.974844
> 0.020000    -1.044042    -0.982954    -0.939136
> 0.040000    -0.958650    -0.880464    -0.881684
> 0.060000    -0.900585    -0.736330    -0.794391
> 0.080000    -0.836541    -0.572538    -0.687577
> 0.100000    -0.747026    -0.457461    -0.573687
> 0.120000    -0.643660    -0.390060    -0.541646
> 0.140000    -0.616448    -0.321599    -0.549098
> 0.160000    -0.563586    -0.251571    -0.546965
> 0.180000    -0.491574    -0.176946    -0.526960
> 0.200000    -0.474667    -0.097256    -0.487377
>
>
> MDP:
>
> ; VARIOUS PREPROCESSING OPTIONS
> title                    =
> ; Preprocessor - specify a full path if necessary.
> cpp                      = \\winsc\mvs8\VC\bin\AMD64\CL /EP
> include                  =
> define                   =
>
> ; RUN CONTROL PARAMETERS
> integrator               = md
> ; Start time and timestep in ps
> tinit                    = 0
> dt                       = .002
> nsteps                   = 100
> ; For exact run continuation or redoing part of a run
> init_step                = 0
> ; mode for center of mass motion removal
> comm-mode                = Linear
> ; number of steps for center of mass motion removal
> nstcomm                  = 1
> ; group(s) for center of mass motion removal
> comm-grps                =
>
> ; OUTPUT CONTROL OPTIONS
> ; Output frequency for coords (x), velocities (v) and forces (f)
> nstxout                  = 10
> nstvout                  = 0
> nstfout                  = 0
>
> ; Output frequency for energies to log file and energy file
> nstlog                   = 100
> nstenergy                = 100
> ; Output frequency and precision for xtc file
> nstxtcout                = 0
> xtc-precision            = 1000
>
> nstlist                  = 10
> ; ns algorithm (simple or grid)
> ns-type                  = Grid
> ; Periodic boundary conditions: xyz (default), no (vacuum)
> ; or full (infinite systems only)
> pbc                      = xyz
> ; nblist cut-off
> rlist                    = 1.2
> domain-decomposition     = no
>
> ; OPTIONS FOR ELECTROSTATICS AND VDW
> ; Method for doing electrostatics
> coulombtype              = pme
> rcoulomb-switch          = 0
> rcoulomb                 = 1.2
> ; Relative dielectric constant for the medium and the reaction field
> epsilon_r                = 1
> epsilon_rf               = 1
> ; Method for doing Van der Waals
> vdwtype                  = switch
> ; cut-off lengths
> rvdw-switch              = 0.8
> rvdw                     = 0.9
> ; Apply long range dispersion corrections for Energy and Pressure
> dispcorr                 = EnerPres
>
> ; OPTIONS FOR WEAK COUPLING ALGORITHMS
> ; Temperature coupling
> tcoupl                   = nose-hoover
> ; Groups to couple separately
> tc-grps                  = System
> ; Time constant (ps) and reference temperature (K)
> tau-t                    = 1.0
> ref_t                    = 298
> ; Pressure coupling
> pcoupl                   = Parrinello-Rahman
> Pcoupltype               = semiisotropic
> ; Time constant (ps), compressibility (1/bar) and reference P (bar)
> tau_p                    = 1.0  1.0
> compressibility          = 4.5e-5 4.5e-5
> ref_p                    = 1.01  1.01
>
> ; GENERATE VELOCITIES FOR STARTUP RUN
> gen_vel                  = yes
> gen-temp                 = 298
> gen-seed                 = -1
>
> ; OPTIONS FOR BONDS
> constraints              = all-bonds
>
> PPA:
>
> ;
> ;    File 'NeRh50_PMF_0.04.ppa' was generated
> ;    By user: onbekend (0)
> ;    On host: onbekend
> ;    At date: Tue Jan 29 21:18:47 2008
> ;
> ; GENERAL
> verbose                  = no
> Skip steps               = 10
> ; Runtype: afm, constraint, umbrella
> runtype                  = umbrella
> ; Number of pull groups
> ngroups                  = 3
> ; Groups to be pulled
> group_1                  = AMM1
> group_2                  = AMM2
> group_3                  = AMM3
> ; The group for the reaction force.
> reference_group          = Backbone
> ; Weights for all atoms in each group (default all 1)
> weights_1                =
> weights_2                =
> weights_3                =
> reference_weights        =
> ; Ref. type: com, com_t0, dynamic, dynamic_t0
> reftype                  = com
> ; Use running average for reflag steps for com calculation
> reflag                   = 1
> ; Select components for the pull vector. default: Y Y Y
> pulldim                  = N N Y
> ; DYNAMIC REFERENCE GROUP OPTIONS
> ; Cylinder radius for dynamic reaction force groups (nm)
> r                        = 0
> ; Switch from r to rc in case of dynamic reaction force
> rc                       = 0
> ; Update frequency for dynamic reference groups (steps)
> update                   = 1
>
> ; CONSTRAINT RUN OPTIONS
> ; Direction, default: 0 0 0, no direction
> constraint_direction     = 0.0 0.0 0.0
> ; Constraint distance (nm), default: 0, use starting distance
> constraint_distance1     = 0
> constraint_distance2     = 0
> constraint_distance3     = 0
> ; Rate of chance of the constraint length, in nm/ps
> constraint_rate1         = 0
> constraint_rate2         = 0
> constraint_rate3         = 0
> ; Tolerance of constraints, in nm
> constraint_tolerance     = 1e-06
>
> ; AFM OPTIONS
> ; Pull rates in nm/ps
> afm_rate1                = .000
> afm_rate2                = .000
> afm_rate3                = .000
> ; Force constants in kJ/(mol*nm^2)
> afm_k1                   = 0.0
> afm_k2                   = 0.0
> afm_k3                   = 0.0
> ; Directions
> afm_dir1                 = 0.0 0.0 0.0
> afm_dir2                 = 0.0 0.0 0.0
> afm_dir3                 = 0.0 0.0 0.0
> ; Initial spring positions
> afm_init1                = 0.0 0.0 0.0
> afm_init2                = 0.0 0.0 0.0
> afm_init3                = 0.0 0.0 0.0
>
> ; UMBRELLA SAMPLING OPTIONS
> ; Force constants for umbrella sampling in kJ/(mol*nm^2)
> ; Centers of umbrella potentials with respect to reference:
> ; Ref - Pull.
> k1                       = 3000
> pos1                     = 0.0 0.0 1.0
> K2                       = 3000
> pos2                     = 0.0 0.0 1.0
> K3                       = 3000
> pos3                     = 0.0 0.0 1.0
>
>
>
>
> --
> Ilya Chorny Ph.D.
>



-- 
Ilya Chorny Ph.D.
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