[gmx-users] Re: gmx-users Digest, Vol 51, Issue 50

Justin A. Lemkul jalemkul at vt.edu
Sun Jul 13 15:55:22 CEST 2008



Biswaranjan Meher wrote:
> Hello Justin.
> Nice to hear from you.
> 
> I did the conversion of AMBER files to GROMACS type by the amb2gmx.pl 
> found in the ffAMBER tools.
> 
> I used the command:
> g_hbond -f input.pdb -s topol.tpr -n index.ndx -num hbnum.xvg -hbn 
> hbond.ndx  -hbm hbmap.xpm -r 0.4
> 
> My input was a pdb file generated from the AMBER trajectory (mdcrd).
> 
> I checked the .gro file (onverted from AMBER) with gmxcheck, of which 
> output is here I am pasting. Just have a look.
> 
> Checking file notty.gro
> Reading frames from gro file 'notty.gro created by rdparm2gmx.pl Fri Jul 
> 11 17:38:48 IST 2008', 30261 atoms.
> Reading frame       0 time    0.000
> # Atoms  30261
> Precision 0.001 (nm)
> Last frame          0 time    0.000
> 
> Item        #frames Timestep (ps)
> Step             0
> Time             0
> Lambda           0
> Coords           1
> Velocities       0
> Forces           0
> Box              1
> 
> Can you please suggest , what may be the possible error from this ?

Well, from what it shows here, your "input.pdb" file has only one frame, or at 
least, only one frame with valid coordinates and box dimensions.  I don't know 
much about amb2gmx.pl, but I thought it's intent was to create a .top and .gro 
from an AMBER-(xleap-)generated prmtop and inpcrd file.  Please someone correct 
me if I'm wrong.

Just recently, I developed my own shell script to convert an mdcrd to an .xtc 
file, since a member of our lab need for some Gromacs analysis tools.  Feel free 
to download it from my site:

http://www.bevanlab.biochem.vt.edu/Pages/Personal/justin/scripts.html

The script has *not* been extensively tested, and I do not promise it will work, 
but I am happy to try to help if problems arise.  If bugs pop up, it will be 
good to know to help make the script better :-)

-Justin

> 
> BRM
> 
> 
> 
> gcq#254: "O My God, They Killed Kenny !" (South Park)
> 
> On Sun, Jul 13, 2008 at 12:19 PM, <gmx-users-request at gromacs.org 
> <mailto:gmx-users-request at gromacs.org>> wrote:
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>     Today's Topics:
> 
>       1. error in g_hbond (Biswaranjan Meher)
>       2. Re: Can GROMACS mutate a residue? (Lee Soin)
>       3. Re: error in g_hbond (Justin A. Lemkul)
>       4. PME User (Sang-Min Park)
>       5. Re: PME User (David van der Spoel)
>       6. gromacs bond type (prasun kumar)
> 
> 
>     ----------------------------------------------------------------------
> 
>     Message: 1
>     Date: Sat, 12 Jul 2008 17:48:04 +0530
>     From: "Biswaranjan Meher" <biswaranjan.meher at gmail.com
>     <mailto:biswaranjan.meher at gmail.com>>
>     Subject: [gmx-users] error in g_hbond
>     To: gmx-users at gromacs.org <mailto:gmx-users at gromacs.org>
>     Message-ID:
>            <b4c1302e0807120518p56d514cfpa98e69b521051c54 at mail.gmail.com
>     <mailto:b4c1302e0807120518p56d514cfpa98e69b521051c54 at mail.gmail.com>>
>     Content-Type: text/plain; charset="iso-8859-1"
> 
>     Dear GROMACS users,
>     I am new to gmx-users.
> 
>     I am analysing the H-bonding in my trajectory with the tool g_hbond.
>     The trajectory was generated by the AMBER force fields.
>     Now I have converted the AMBER prmtop and inpcrd files to GROMACS
>     .top and
>     .gro files.
> 
>     When I performed the g_hbond, I encountered with a fatal error
> 
>     Your computational box has shrunk too much.
>     g_hbond can not handle this situation, sorry.
> 
>     Also I checked the postings in the archive related to this problem,
>     but I
>     didnt get the solution completely.
>     So is it a problem of my AMBER traj./pdb files I am using or it some
>     thing
>     else.
>     Can anyone will help me in this regard to get the solution ?
> 
>     Thanks in advance for your kind suggestions.
> 
>     BRM
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>     ------------------------------
> 
>     Message: 2
>     Date: Sat, 12 Jul 2008 20:44:45 +0800
>     From: "Lee Soin" <nomadoro at gmail.com <mailto:nomadoro at gmail.com>>
>     Subject: Re: [gmx-users] Can GROMACS mutate a residue?
>     To: "Discussion list for GROMACS users" <gmx-users at gromacs.org
>     <mailto:gmx-users at gromacs.org>>
>     Message-ID:
>            <e2838e4e0807120544t2d8c0858g1949a805131ba436 at mail.gmail.com
>     <mailto:e2838e4e0807120544t2d8c0858g1949a805131ba436 at mail.gmail.com>>
>     Content-Type: text/plain; charset="iso-8859-1"
> 
>     Thanks! And I've learned that Pymol can also do the job.
> 
>     2008/7/12 DEEPESH AGARWAL <deepesh.iitd at gmail.com
>     <mailto:deepesh.iitd at gmail.com>>:
> 
>      > Hi,
>      >
>      > In addition to what Justin has suggested, VMD has a tool to mutate a
>      > residue- Extensions>Modeling>Mutate residue.
>      >
>      > Deepesh
>      >
>      >
>      > On 7/12/08, Justin A. Lemkul <jalemkul at vt.edu
>     <mailto:jalemkul at vt.edu>> wrote:
>      > >
>      > >
>      > > Lee Soin wrote:
>      > >> Hi!
>      > >> Is there a command in GROMACS that can substitute the atoms of
>     a whole
>      > >> residue for another? This is quite useful in doing mutation
>     simulations.
>      > >> Or if that's not possible, how should I mutate a residue? Thanks!
>      > >
>      > > I would use a program like DeepView (Swiss-PDBViewer), or maybe
>     Modeller.
>      > >
>      > > -Justin
>      > >
>      > >>
>      > >> --
>      > >> Sun Li
>      > >> Department of Physics
>      > >> Nanjing University, China
>      > >>
>      > >>
>      > >>
>     ------------------------------------------------------------------------
>      > >>
>      > >> _______________________________________________
>      > >> gmx-users mailing list    gmx-users at gromacs.org
>     <mailto:gmx-users at gromacs.org>
>      > >> http://www.gromacs.org/mailman/listinfo/gmx-users
>      > >> Please search the archive at http://www.gromacs.org/search before
>      > posting!
>      > >> Please don't post (un)subscribe requests to the list. Use the
>      > >> www interface or send it to gmx-users-request at gromacs.org
>     <mailto:gmx-users-request at gromacs.org>.
>      > >> Can't post? Read http://www.gromacs.org/mailing_lists/users.php
>      > >
>      > > --
>      > > ========================================
>      > >
>      > > Justin A. Lemkul
>      > > Graduate Research Assistant
>      > > Department of Biochemistry
>      > > Virginia Tech
>      > > Blacksburg, VA
>      > > jalemkul[at]vt.edu <http://vt.edu> | (540) 231-9080
>      > > http://www.bevanlab.biochem.vt.edu/Pages/Personal/justin
>      > >
>      > > ========================================
>      > > _______________________________________________
>      > > gmx-users mailing list    gmx-users at gromacs.org
>     <mailto:gmx-users at gromacs.org>
>      > > http://www.gromacs.org/mailman/listinfo/gmx-users
>      > > Please search the archive at http://www.gromacs.org/search before
>      > posting!
>      > > Please don't post (un)subscribe requests to the list. Use the
>      > > www interface or send it to gmx-users-request at gromacs.org
>     <mailto:gmx-users-request at gromacs.org>.
>      > > Can't post? Read http://www.gromacs.org/mailing_lists/users.php
>      > >
>      > _______________________________________________
>      > gmx-users mailing list    gmx-users at gromacs.org
>     <mailto:gmx-users at gromacs.org>
>      > http://www.gromacs.org/mailman/listinfo/gmx-users
>      > Please search the archive at http://www.gromacs.org/search before
>     posting!
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>      > www interface or send it to gmx-users-request at gromacs.org
>     <mailto:gmx-users-request at gromacs.org>.
>      > Can't post? Read http://www.gromacs.org/mailing_lists/users.php
>      >
> 
> 
> 
>     --
>     Sun Li
>     Department of Physics
>     Nanjing University, China
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>     ------------------------------
> 
>     Message: 3
>     Date: Sat, 12 Jul 2008 09:11:24 -0400
>     From: "Justin A. Lemkul" <jalemkul at vt.edu <mailto:jalemkul at vt.edu>>
>     Subject: Re: [gmx-users] error in g_hbond
>     To: Discussion list for GROMACS users <gmx-users at gromacs.org
>     <mailto:gmx-users at gromacs.org>>
>     Message-ID: <4878AD7C.8090504 at vt.edu <mailto:4878AD7C.8090504 at vt.edu>>
>     Content-Type: text/plain; charset=ISO-8859-1; format=flowed
> 
> 
> 
>     Biswaranjan Meher wrote:
>      > Dear GROMACS users,
>      > I am new to gmx-users.
>      >
>      > I am analysing the H-bonding in my trajectory with the tool g_hbond.
>      > The trajectory was generated by the AMBER force fields.
>      > Now I have converted the AMBER prmtop and inpcrd files to GROMACS
>     .top
>      > and .gro files.
> 
>     How did you do this conversion?
> 
>      >
>      > When I performed the g_hbond, I encountered with a fatal error
> 
>     What was the command you issued?  Were you analyzing the .gro file,
>     or some
>     converted mdcrd file?
> 
>      >
>      > Your computational box has shrunk too much.
>      > g_hbond can not handle this situation, sorry.
>      >
>      > Also I checked the postings in the archive related to this
>     problem, but
>      > I didnt get the solution completely.
>      > So is it a problem of my AMBER traj./pdb files I am using or it some
>      > thing else.
>      > Can anyone will help me in this regard to get the solution ?
> 
>     Use gmxcheck on whatever files you have tried to analyze to see if
>     they contain
>     the appropriate box vectors.  I don't know how you did the
>     conversion of the
>     files from AMBER --> GROMACS, so that's a possible source of error.
> 
>     -Justin
> 
>      >
>      > Thanks in advance for your kind suggestions.
>      >
>      > BRM
>      >
>      >
>      >
>     ------------------------------------------------------------------------
>      >
>      > _______________________________________________
>      > gmx-users mailing list    gmx-users at gromacs.org
>     <mailto:gmx-users at gromacs.org>
>      > http://www.gromacs.org/mailman/listinfo/gmx-users
>      > Please search the archive at http://www.gromacs.org/search before
>     posting!
>      > Please don't post (un)subscribe requests to the list. Use the
>      > www interface or send it to gmx-users-request at gromacs.org
>     <mailto:gmx-users-request at gromacs.org>.
>      > Can't post? Read http://www.gromacs.org/mailing_lists/users.php
> 
>     --
>     ========================================
> 
>     Justin A. Lemkul
>     Graduate Research Assistant
>     Department of Biochemistry
>     Virginia Tech
>     Blacksburg, VA
>     jalemkul[at]vt.edu <http://vt.edu> | (540) 231-9080
>     http://www.bevanlab.biochem.vt.edu/Pages/Personal/justin
> 
>     ========================================
> 
> 
>     ------------------------------
> 
>     Message: 4
>     Date: Sat, 12 Jul 2008 17:40:06 +0200
>     From: Sang-Min Park <sanni at theochem.uni-frankfurt.de
>     <mailto:sanni at theochem.uni-frankfurt.de>>
>     Subject: [gmx-users] PME User
>     To: gmx-users at gromacs.org <mailto:gmx-users at gromacs.org>
>     Message-ID: <200807121740.06885.sanni at theochem.uni-frankfurt.de
>     <mailto:200807121740.06885.sanni at theochem.uni-frankfurt.de>>
>     Content-Type: text/plain;  charset="iso-8859-1"
> 
> 
>     Dear all,
> 
>     I read in www.gromacs.org/gromacs/revisions/
>     <http://www.gromacs.org/gromacs/revisions/>  in the report of
>     David van der Spoel
> 
>      "Added support for a combination of PME and User determined coulomb
>      potentials. The user has to take care that the combination of
>     Coulomb and
>      standard PME makes sense"  ( 8 Feb. 2005)
> 
>      I don't understand what that means.
> 
>      As I know the Ewald Sum consist of the reciprocal and direct space term
>      which are derivated for the f(x)=1/r function.
> 
>      In this sense I don't know what gromacs would do when I would specify
>      PME-User with a potential that is different from f(x).
> 
>     1.  Can someone explain me what gromacs is doing when one sets
>     PME-User ?    
> 
>     2. Furthermore I would like to know if the user defined potential
>     tables are
>     also used to calculate the long range interactions.
> 
>     Thank you for your time
> 
> 
>     ------------------------------
> 
>     Message: 5
>     Date: Sat, 12 Jul 2008 17:49:22 +0200
>     From: David van der Spoel <spoel at xray.bmc.uu.se
>     <mailto:spoel at xray.bmc.uu.se>>
>     Subject: Re: [gmx-users] PME User
>     To: Discussion list for GROMACS users <gmx-users at gromacs.org
>     <mailto:gmx-users at gromacs.org>>
>     Message-ID: <4878D282.3050501 at xray.bmc.uu.se
>     <mailto:4878D282.3050501 at xray.bmc.uu.se>>
>     Content-Type: text/plain; charset=ISO-8859-1; format=flowed
> 
>     Sang-Min Park wrote:
>      > Dear all,
>      >
>      > I read in www.gromacs.org/gromacs/revisions/
>     <http://www.gromacs.org/gromacs/revisions/>  in the report of
>      > David van der Spoel
>      >
>      >  "Added support for a combination of PME and User determined coulomb
>      >  potentials. The user has to take care that the combination of
>     Coulomb and
>      >  standard PME makes sense"  ( 8 Feb. 2005)
>      >
>      >  I don't understand what that means.
>      >
>      >  As I know the Ewald Sum consist of the reciprocal and direct
>     space term
>      >  which are derivated for the f(x)=1/r function.
>      >
>      >  In this sense I don't know what gromacs would do when I would
>     specify
>      >  PME-User with a potential that is different from f(x).
>      >
>      > 1.  Can someone explain me what gromacs is doing when one sets
>     PME-User ?
> 
>     Let's say you want to replace the Coulomb potential Fc(r) by your own
>     Fuser(r). Then you have to subtract the Long Range part of the coulomb
>     potential Fc(r,LR) from your F(r) in the short range potential to get
>     the correct sum. Note that this also dependent on the cut-off, so if you
>     decide to change the cut-off you need a new lookup table for the
>     short-range.
> 
>      >
>      > 2. Furthermore I would like to know if the user defined potential
>     tables are
>      > also used to calculate the long range interactions.
>      >
>      > Thank you for your time
>      > _______________________________________________
>      > gmx-users mailing list    gmx-users at gromacs.org
>     <mailto:gmx-users at gromacs.org>
>      > http://www.gromacs.org/mailman/listinfo/gmx-users
>      > Please search the archive at http://www.gromacs.org/search before
>     posting!
>      > Please don't post (un)subscribe requests to the list. Use the
>      > www interface or send it to gmx-users-request at gromacs.org
>     <mailto:gmx-users-request at gromacs.org>.
>      > Can't post? Read http://www.gromacs.org/mailing_lists/users.php
> 
> 
>     --
>     David van der Spoel, Ph.D., Professor of Biology
>     Molec. Biophys. group, Dept. of Cell & Molec. Biol., Uppsala University.
>     Box 596, 75124 Uppsala, Sweden. Phone:  +46184714205. Fax: +4618511755.
>     spoel at xray.bmc.uu.se <mailto:spoel at xray.bmc.uu.se>  
>      spoel at gromacs.org <mailto:spoel at gromacs.org>   http://folding.bmc.uu.se
> 
> 
>     ------------------------------
> 
>     Message: 6
>     Date: Sun, 13 Jul 2008 12:18:41 +0530
>     From: "prasun kumar" <prasun30 at gmail.com <mailto:prasun30 at gmail.com>>
>     Subject: [gmx-users] gromacs bond type
>     To: gmx-users at gromacs.org <mailto:gmx-users at gromacs.org>
>     Message-ID:
>            <a473abdb0807122348v52f1dcfcw5b4241794eabb536 at mail.gmail.com
>     <mailto:a473abdb0807122348v52f1dcfcw5b4241794eabb536 at mail.gmail.com>>
>     Content-Type: text/plain; charset="iso-8859-1"
> 
>     dear users,
>     I am trying to get some information about the bond type,angle type and
>     dihedral angle type.
>     can any one please tell me what is the bond type of C-F.angle type for
>     F-C-F,dihedral angle type of F-C-C-O &F-C-C-H.
>     Or any one can tell me how to define the gromacs type for bonds,angles.I
>     tried to read the 5th chapter but not getting any thing.
>     actually i am lookig forward to include TFE in the rtp file for my
>     simulation of peptide in TFE.
>     Please help me.
>     Thanx in advance
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> 
>     _______________________________________________
>     gmx-users mailing list
>     gmx-users at gromacs.org <mailto:gmx-users at gromacs.org>
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>     Please search the archive at http://www.gromacs.org/search before
>     posting!
> 
>     End of gmx-users Digest, Vol 51, Issue 50
>     *****************************************
> 
> 
> 
> ------------------------------------------------------------------------
> 
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-- 
========================================

Justin A. Lemkul
Graduate Research Assistant
Department of Biochemistry
Virginia Tech
Blacksburg, VA
jalemkul[at]vt.edu | (540) 231-9080
http://www.bevanlab.biochem.vt.edu/Pages/Personal/justin

========================================



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