[gmx-users] Crashing NPT run, 1.5 ns

JMandumpal jesbman at rediffmail.com
Wed May 28 14:22:43 CEST 2008


Dear list,

I was running AA acetone in tip4p water simulation  for calculating average density : NPT for 1.5 ns, but, after 600 ps the simulation crashes . I came to know from older posts, this may result with an inappropriate value of P-couple. I increased the value from 0.4, which was using before, to 5.0,  still the simulation crashes. I paste the error message, the input file for the simulation and the parameter file for acetone. Could you please point out where I did make mistake.
regards,
Jestin    
*************************************************
Error message from a program output file:
****************************************************
Reading file binary.tpr, VERSION 3.3.3 (double precision)
starting mdrun 'Pure water - acetone'
750000 steps,   1500.0 ps.
                                                                                
Wrote pdb files with previous and current coordinates
                                                                                
Back Off! I just backed up step281955.pdb to ./#step281955.pdb.1#
Wrote pdb files with previous and current coordinates
MPI: On host cognac, Program /opt/gromacs/3.3.3/bin/mdrun, Rank 2, Process 2410 received signal SIGSEGV(11)
                                                                                
                                                                                
MPI: --------stack traceback-------
sh: idb: command not found
                                                                                
MPI: -----stack traceback ends-----
MPI: On host cognac, Program /opt/gromacs/3.3.3/bin/mdrun, Rank 2, Process 2410: Dumping core on signal SIGSEGV(11) into directory /short/bm01/jestin/acetone/40/180
MPI: MPI_COMM_WORLD rank 2 has terminated without calling MPI_Finalize()
MPI: aborting job

****************************************************************  
my input file (.mdp file):
------------------------------------------------------
title                    = ACETONE
cpp                      = /usr/bin/cpp
; RUN CONTROL PARAMETERS
integrator               = md
; Start time and timestep in ps
dt                       = 0.002 ;  2 fs
nsteps                   = 750000  ; 1500ps
; For exact run continuation or redoing part of a run
init_step                = 0
; number of steps for center of mass motion removal
nstcomm                  = 1
; group(s) for center of mass motion removal
comm-grps                = system
; OUTPUT CONTROL OPTIONS
; Output frequency for coords (x), velocities (v) and forces (f)
nstxout                  = 0
nstvout                  = 0
nstfout                  = 0
; Checkpointing helps you continue after crashes
nstcheckpoint            = 1000
; Output frequency for energies to log file and energy file
nstlog                   = 0
nstenergy                = 10000
; Output frequency and precision for xtc file
nstxtcout                = 0
xtc-precision            = 1000
; select multiple groups. By default all atoms will be written.
; NEIGHBORSEARCHING PARAMETERS
nstlist                  = 10
; ns algorithm (simple or grid)
ns_type                  = grid
; Periodic boundary conditions:
pbc                      = xyz
; nblist cut-off
rlist                    = 1.0
; OPTIONS FOR ELECTROSTATICS AND VDW
; Method for doing electrostatics
coulombtype              = pme
rcoulomb                 = 1.0
ewald_rtol               = 1.0e-5  ; since erfc(sigma*rcutoff)=ewald_rtol
optimize_fft             = yes
; Relative dielectric constant for the medium
epsilon_r                = 1  ; for water
; Method for doing Van der Waals
vdw-type                 = cut-off
rvdw                     = 1.0
; Spacing for the PME/PPPM FFT grid
fourierspacing           = 0.12
; EWALD/PME/PPPM parameters
pme_order                = 4
ewald_geometry           = 3d
epsilon_surface          = 0
; OPTIONS FOR WEAK COUPLING ALGORITHMS
; Temperature coupling
Tcoupl                   = berendsen
; Groups to couple separately
tc-grps                  = system
; Time constant (ps) and reference temperature (K)
tau-t                    = 0.1
ref-t                    = 180
; Pressure coupling
Pcoupl                   = berendsen
Pcoupltype               = Isotropic
; Time constant (ps), compressibility (1/bar) and reference P (bar)
tau-p                    = 5.0
compressibility          = 4.5e-5
ref-p                    = 1.0
; GENERATE VELOCITIES FOR STARTUP RUN
gen_vel                  = yes
gen-temp                 = 180
gen-seed                 = 173529
constraints              = all-bonds
constraint_algorithm     = shake
shake_tol                = 0.0001
morse                    = no
**********************************************************************
acetone parameter file:
----------------------------------------------
[ moleculetype ]
; Name nrexcl JPC 94, 1685
  ACET   3
                                                                                                                                                                                                                                  
[ atoms ]
;   nr     type     resnr resid  atom   cgnr  charge   mass
     1    opls_280   1    ACET    C_2     1    0.470  12.0110
     2    opls_281   1    ACET    O_2     1   -0.470  15.9994
     3    opls_135   1    ACET    CT1     2   -0.180  12.0110
     4    opls_282   1    ACET    HC1     2    0.060  1.00800
     5    opls_282   1    ACET    HC2     2    0.060  1.00800
     6    opls_282   1    ACET    HC3     2    0.060  1.00800
     7    opls_135   1    ACET    CT2     3   -0.180  12.0110
     8    opls_282   1    ACET    HC4     3    0.060  1.00800
     9    opls_282   1    ACET    HC5     3    0.060  1.00800
    10    opls_282   1    ACET    HC6     3    0.060  1.00800
                                                                                                                                                                                                                                  
[ bonds ]
; ai  aj  fu    c0, c1, ...
   1   2   1    0.12290   476976.0  ;   C_2  O_2 ketone group
   3   1   1    0.15220   265265.6  ;   C_2  CT1 methylcarbon - keto carbon
   7   1   1    0.15220   265265.6  ;   C_2  CT1 methylcarbon - keto carbon
   3   4   1    0.10900   284512.0  ;   CT1  HC1 methylC- hydrogen
   3   5   1    0.10900   284512.0  ;   CT1  HC2 methylC- hydrogen
   3   6   1    0.10900   284512.0  ;   CT1  HC3 methylC- hydrogen
   7   8   1    0.10900   284512.0  ;   CT2  HC4 methylC- hydrogen
   7   9   1    0.10900   284512.0  ;   CT2  HC5 methylC- hydrogen
   7  10   1    0.10900   284512.0  ;   CT2  HC6 methylC- hydrogen
                                                                                                                                                                                                                                  
[ angles ]
; ai  aj  ak  fu    c0, c1, ...
   3   1   7   1    116.00      585.760 ;   CT1  C_2 CT2
   3   1   2   1    120.40      669.440 ;   CT1  C_2 O_2
   4   3   1   1    109.50      292.880 ;   HC1  CT1 C_2
   5   3   1   1    109.50      292.880 ;   HC1  CT1 C_2
   7   1   2   1    120.40      669.440 ;   CT2  C_2 0_2
   8   7   1   1    109.50      292.880 ;   HC4  CT2 C_2
   9   7   1   1    109.50      292.880 ;   HC4  CT2 C_2
  10   7   1   1    109.50      292.880 ;   HC4  CT2 C_2
                                                                                                                                                                                                                                  
                                                                                                                                                                                                                                  
[ dihedrals ]
; ai  aj  ak  al  fu    c0, c1, m, ...
  7   1   3   4     3      0.57530   1.72590   0.00000  -2.30120   0.00000   0.00000 ; ketone
  7   1   3   5     3      0.57530   1.72590   0.00000  -2.30120   0.00000   0.00000 ; ketone
  7   1   3   6     3      0.57530   1.72590   0.00000  -2.30120   0.00000   0.00000 ; ketone
  3   1   7   8     3      0.57530   1.72590   0.00000  -2.30120   0.00000   0.00000 ; ketone
  3   1   7   8     3      0.57530   1.72590   0.00000  -2.30120   0.00000   0.00000 ; ketone
  3   1   7   8     3      0.57530   1.72590   0.00000  -2.30120   0.00000   0.00000 ; ketone
  4   3   1   2     3      0.00000   0.00000   0.00000   0.00000   0.00000   0.00000
  5   3   1   2     3      0.00000   0.00000   0.00000   0.00000   0.00000   0.00000
  6   3   1   2     3      0.00000   0.00000   0.00000   0.00000   0.00000   0.00000
  8   7   1   2     3      0.00000   0.00000   0.00000   0.00000   0.00000   0.00000
  9   7   1   2     3      0.00000   0.00000   0.00000   0.00000   0.00000   0.00000
 10   7   1   2     3      0.00000   0.00000   0.00000   0.00000   0.00000   0.00000
  3   7   1   2     3      3.10662  -3.77606  -5.13795   5.80739   0.00000   0.00000 ;  ketone improper dihedral
                                                                                                                                                                                                                                  

                 
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