Fwd: [gmx-users] Invalid atom number 6415 in indexfile

Mark Abraham Mark.Abraham at anu.edu.au
Thu Jan 29 01:31:36 CET 2009


Liu Shiyong wrote:
> Hi,

> 
> *Step 2:*
> Starting structure:  clean2.pdb
> 
> I am trying to calculate the energy according to energy groups
> 
> 
> pdb2gmx   -ff G53a6 -f clean2.pdb -p clean2_0.6.top -i 
> clean2_0.6.posre.itp -o clean2_0.6.gro > clean2_0.6.output.pdb2gmx 2>&1
> 
> make_ndx -f clean2.pdb  -o clean2_0.6.ndx < ./make_ndx.input > 
> clean2_0.6.output.make_ndx 2>&1

So here you made some energy groups from the *input* to pdb2gmx. Make it 
from the *output* from pdb2gmx and you will be sure things correspond to 
the topology *output* from pdb2gmx. It seems rather obvious to me that 
your input to make_ndx has all the hydrogens still in it.

> em.mdp
> 
> title               =  clean2_0.6
> cpp                 =  /usr/bin/cpp
> integrator          =  cg
> dt                  =  0.002    ; ps !
> nsteps              =  1
> rlist               =  0.55
> nstlist             =  0
> vdwtype             =  Cut-off
> rvdw                =  0.6
> coulombtype         =  shift
> epsilon_r           =  20000
> rcoulomb            =  0.6
> rcoulomb-switch     =  0.55
> energy_grps         =  chB chA
> ;
> ;       Energy minimizing stuff
> ;
> emtol               =  100.0
> emstep              =  0.01
> 
> 
> grompp -maxwarn 10 -f em.mdp -c clean2_0.6.gro -n clean2_0.6.ndx -p 
> clean2_0.6.top -o clean2_0.6.input.tpr > clean2_0.6.output.grompp 2>&1
> 
> Then, I got an error msg:
> 
> 
> clean2_0.6.output.grompp
> 
> -------------------------------------------------------
> Program grompp, VERSION 3.3.3
> Source code file: ../../../../src/kernel/grompp.c, line: 307
> 
> Fatal error:
> atoms 4175 and 4183 in charge group 1767 are in different energy groups
> -------------------------------------------------------
> 
> "God is a DJ" (Faithless)
> 
> 
> 
> 
> 
> 
> 
> 
> 
> 
> 
> 
> 
> 
> 
> 
> 
> 
> 
> 
> On Wed, Jan 28, 2009 at 12:28 PM, Justin A. Lemkul <jalemkul at vt.edu 
> <mailto:jalemkul at vt.edu>> wrote:
> 
> 
> 
>     Liu Shiyong wrote:
> 
>         Hi,
> 
>         Did you get my script ?  
> 
> 
>     As I said just a few days ago, I don't run jobs for people.  I only
>     have allocated time on our University's cluster, which I need for
>     myself.
> 
>     That said, it is also very difficult to go through someone's
>     scripting, laden with variables that mean nothing to anyone else but
>     you, and come up with something meaningful, especially when everyone
>     on this list has their own work to be doing.  As I've said several
>     times, simply posting your command lines with the relevant error
>     message(s) is sufficient.
> 
>     That said, I really have no clue what you're doing with those
>     scripts.  It appears that you are running pdb2gmx, grompp, and
>     mdrun, then using trjconv to dump out the last frame from your
>     energy minimization.  The last step is certainly not necessary;
>     mdrun outputs the lowest-energy coordinates.
> 
>     Then you are running pdb2gmx again, and creating index groups.  I
>     don't understand the purpose of the second pdb2gmx call.
> 
>     The problem you are facing is easily answered with the fact that you
>     simply are again using a structure file that does not have the same
>     number of atoms as the structure you used to create the index file.
>      It appears that your index files simply have two chains of a
>     protein, with the highest atom number being 5966. So of course atom
>     6415 is missing.  The simple fix is to perhaps simplify your naming
>     strategy so you can keep it straight, or instead of scripting
>     everything and potentially making mistakes, to just run the commands
>     interactively until you have everything flowing.
> 
>     -Justin
> 
>         I dump a frame from .trr file.
>         I did not define xtc-grps
>          
>         On Wed, Jan 21, 2009 at 2:00 PM, Justin A. Lemkul
>         <jalemkul at vt.edu <mailto:jalemkul at vt.edu>
>         <mailto:jalemkul at vt.edu <mailto:jalemkul at vt.edu>>> wrote:
> 
> 
> 
>            Liu Shiyong wrote:
> 
>                Hi,
> 
>                 I got an error when do grompp:   The input PDB file
>         comes from
>                the output of GROMACS by trajconv command.
> 
> 
>            <snip>
> 
>                -------------------------------------------------------
>                Program grompp, VERSION 3.3.3
>                Source code file: ../../../../src/kernel/readir.c, line: 838
> 
>                *Fatal error:
>                Invalid atom number 6415 in indexfile*
>                -------------------------------------------------------
> 
> 
>            Instead of screen dumps, it would be a lot more useful to see
>         your
>            .mdp file, as well as the command line (not output from) both
>         grompp
>            and trjconv.  Did you dump the frame from an .xtc file?  What did
>            you specify in xtc-grps?
> 
>            -Justin
> 
>            --    ========================================
> 
>            Justin A. Lemkul
>            Graduate Research Assistant
>            Department of Biochemistry
>            Virginia Tech
>            Blacksburg, VA
>            jalemkul[at]vt.edu <http://vt.edu> <http://vt.edu> | (540)
>         231-9080
> 
>            http://www.bevanlab.biochem.vt.edu/Pages/Personal/justin
> 
>            ========================================
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> 
> 
> 
>         -- 
>         Shiyong Liu
>         Postdoc
>         center for bioinformatics in the university of kansas
>         Lab: (785)864-1962
>         Email: syliu at ku.edu <mailto:syliu at ku.edu> <mailto:syliu at ku.edu
>         <mailto:syliu at ku.edu>> (shiyongliu at ku.edu
>         <mailto:shiyongliu at ku.edu> <mailto:shiyongliu at ku.edu
>         <mailto:shiyongliu at ku.edu>> or liushiyong at ku.edu
>         <mailto:liushiyong at ku.edu> <mailto:liushiyong at ku.edu
>         <mailto:liushiyong at ku.edu>>)
> 
>         Homepage: http://www.people.ku.edu/~syliu
>         <http://www.people.ku.edu/%7Esyliu>
>         Lab:    http://vakser.bioinformatics.ku.edu/people
>         Phone:      (785) 864-1962
> 
> 
>     -- 
>     ========================================
> 
>     Justin A. Lemkul
>     Graduate Research Assistant
>     Department of Biochemistry
>     Virginia Tech
>     Blacksburg, VA
>     jalemkul[at]vt.edu <http://vt.edu> | (540) 231-9080
>     http://www.bevanlab.biochem.vt.edu/Pages/Personal/justin
> 
>     ========================================
> 
> 
> 
> 
> -- 
> Shiyong Liu
> Postdoc
> center for bioinformatics in the university of kansas
> Lab: (785)864-1962
> Email: syliu at ku.edu <mailto:syliu at ku.edu> (shiyongliu at ku.edu 
> <mailto:shiyongliu at ku.edu> or liushiyong at ku.edu <mailto:liushiyong at ku.edu>)
> 
> Homepage: http://www.people.ku.edu/~syliu 
> <http://www.people.ku.edu/%7Esyliu>
> Lab:    http://vakser.bioinformatics.ku.edu/people
> Phone:      (785) 864-1962
> 
> 
> 
> -- 
> Shiyong Liu
> Postdoc
> center for bioinformatics in the university of kansas
> Lab: (785)864-1962
> Email: syliu at ku.edu <mailto:syliu at ku.edu> (shiyongliu at ku.edu 
> <mailto:shiyongliu at ku.edu> or liushiyong at ku.edu <mailto:liushiyong at ku.edu>)
> Homepage: http://www.people.ku.edu/~syliu
> Lab:    http://vakser.bioinformatics.ku.edu/people
> Phone:      (785) 864-1962
> 
> 
> ------------------------------------------------------------------------
> 
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