[gmx-users] grompp, energy minimization,, output file error

Moeed lecielll at googlemail.com
Fri Apr 23 00:52:18 CEST 2010


Dear gmx users,

I am trying to run grompp program to preprocess the input files. input gro
file contains coordinates of a stack of hexane molecules (256 molecules).

grompp -f em -c Hexane-stack.gro -p HexaneModified.top -o Hexane_em -maxwarn
30 >& output.grompp_em


my problem is that output: Hexane_em.tpr contains strange notations:

éxÕ@!`A‰7KÇ?ý"Ðå`A‰@!(r° Äœ@(LÌÌÌÌÍ?û Iº^5@!O\(õ @(LÌÌÌÌÍ?ù n— Oß@!
¾vÈ´9@(LÌÌÌÌÍ?öí‘hr°!@!F§ï
²-@(LÌÌÌÌÍ?ôýó¶E¡Ë@!


output.grompp_em:


  GNU nano 2.0.9                    File:
output.grompp_em


Ignoring obsolete mdp entry 'cpp'

Back Off! I just backed up mdout.mdp to ./#mdout.mdp.1#
checking input for internal consistency...
Opening library file /chem_soft/gromacs/share/gromacs/top/ffoplsaa.itp
Opening library file /chem_soft/gromacs/share/gromacs/top/ffoplsaanb.itp
Opening library file /chem_soft/gromacs/share/gromacs/top/ffoplsaabon.itp
Generated 332520 of the 332520 non-bonded parameter combinations
Generating 1-4 interactions: fudge = 0.5
Generated 332520 of the 332520 1-4 parameter combinations
Excluding 3 bonded neighbours molecule type 'HEX'

NOTE 1 [file HexaneModified.top, line 163]:
  System has non-zero total charge: 2.206157e+04



processing coordinates...

Warning: atom name 1 in HexaneModified.top and Hexane-stack.gro does not
match (1 - C1)
Warning: atom name 2 in HexaneModified.top and Hexane-stack.gro does not
match (1 - C2)
Warning: atom name 3 in HexaneModified.top and Hexane-stack.gro does not
match (1 - C3)
Warning: atom name 4 in HexaneModified.top and Hexane-stack.gro does not
match (1 - C4)
Warning: atom name 5 in HexaneModified.top and Hexane-stack.gro does not
match (1 - C5)
Warning: atom name 6 in HexaneModified.top and Hexane-stack.gro does not
match (1 - C6)
Warning: atom name 7 in HexaneModified.top and Hexane-stack.gro does not
match (1 - H1)
Warning: atom name 8 in HexaneModified.top and Hexane-stack.gro does not
match (1 - H2)
Warning: atom name 9 in HexaneModified.top and Hexane-stack.gro does not
match (1 - H3)
Warning: atom name 10 in HexaneModified.top and Hexane-stack.gro does not
match (1 - H4)
Warning: atom name 11 in HexaneModified.top and Hexane-stack.gro does not
match (1 - H5)
Warning: atom name 12 in HexaneModified.top and Hexane-stack.gro does not
match (1 - H6)
Warning: atom name 13 in HexaneModified.top and Hexane-stack.gro does not
match (1 - H7)
Warning: atom name 14 in HexaneModified.top and Hexane-stack.gro does not
match (1 - H8)
Warning: atom name 15 in HexaneModified.top and Hexane-stack.gro does not
match (1 - H9)
Warning: atom name 16 in HexaneModified.top and Hexane-stack.gro does not
match (1 - H10)
Warning: atom name 17 in HexaneModified.top and Hexane-stack.gro does not
match (1 - H11)

WARNING 1 [file HexaneModified.top, line 163]:
  5120 non-matching atom names
  atom names from HexaneModified.top will be used
  atom names from Hexane-stack.gro will be ignored


double-checking input for internal consistency...
renumbering atomtypes...
converting bonded parameters...

NOTE 2 [file HexaneModified.top, line unknown]:
  The largest charge group contains 20 atoms.
  Since atoms only see each other when the centers of geometry of the charge
  groups they belong to are within the cut-off distance, too large charge
  groups can lead to serious cut-off artifacts.
  For efficiency and accuracy, charge group should consist of a few atoms.
  For all-atom force fields use: CH3, CH2, CH, NH2, NH, OH, CO2, CO, etc.

initialising group options...
processing index file...
Opening library file /chem_soft/gromacs/share/gromacs/top/aminoacids.dat

Making dummy/rest group for T-Coupling containing 5120 elements
Making dummy/rest group for Acceleration containing 5120 elements
Making dummy/rest group for Freeze containing 5120 elements
Making dummy/rest group for Energy Mon. containing 5120 elements
Making dummy/rest group for VCM containing 5120 elements
Number of degrees of freedom in T-Coupling group rest is 15357.00
Making dummy/rest group for User1 containing 5120 elements
Making dummy/rest group for User2 containing 5120 elements
Making dummy/rest group for XTC containing 5120 elements
Making dummy/rest group for Or. Res. Fit containing 5120 elements
Making dummy/rest group for QMMM containing 5120 elements
T-Coupling       has 1 element(s): rest
Energy Mon.      has 1 element(s): rest

Checking consistency between energy and charge groups...

NOTE 3 [file em.mdp, line unknown]:
  You are using a plain Coulomb cut-off, which might produce artifacts.
  You might want to consider using PME electrostatics.


writing run input file...

There were 3 notes

There was 1 warning

Back Off! I just backed up Hexane_em.tpr to ./#Hexane_em.tpr.1#

gcq#312: "Move about like a Scientist, lay down, get kissed" (Red Hot Chili
Peppars)


processing topology...
Analysing residue names:
There are:   256      OTHER residues
There are:     0    PROTEIN residues
There are:     0        DNA residues
Analysing Other...
This run will generate roughly 1 Mb of data


*********************************************************************************************************************


em.mdp file I use:

;title               =  cpeptide
cpp                 =  /lib/cpp
define              =  -DFLEX_SPC
constraints         =  none
integrator          =  steep
dt                  =  0.002    ; ps !
nsteps              =  100
nstlist             =  10
ns_type             =  grid
rlist               =  1.0
rcoulomb            =  1.0
rvdw                =  1.0
;
;       Energy minimizing stuff
;
emtol               =  1000.0
emstep              =  0.01


****************************topology file:

;
;    File 'Hexane.top' was generated
;    By user: moeed (500)
;    On host: moeed-desktop
;    At date: Thu Apr  8 13:51:19 2010
;
;    This is your include topology file
;    Generated by x2top
;
; Include forcefield parameters
#include "ffoplsaa.itp"

[ moleculetype ]
; Name            nrexcl
HEX                 3

[ atoms ]
;   nr       type  resnr residue  atom   cgnr     charge       mass
typeB    chargeB      massB
     1   opls_157      1            C1      1      -0.18     12.011   ; qtot
-0.18
     2   opls_158      1            C2      1      -0.12     12.011   ; qtot
-0.3
     3   opls_158      1            C3      1      -0.12     12.011   ; qtot
-0.42
     4   opls_158      1            C4      1      -0.12     12.011   ; qtot
-0.54
     5   opls_158      1            C5      1      -0.12     12.011   ; qtot
-0.66
     6   opls_157      1            C6      1      -0.18     12.011   ; qtot
-0.84
     7   opls_140      1            H1      1       0.06      1.008   ; qtot
-0.78
     8   opls_140      1            H2      1       0.06      1.008   ; qtot
-0.72
     9   opls_140      1            H3      1       0.06      1.008   ; qtot
-0.66
    10   opls_140      1            H4      1       0.06      1.008   ; qtot
-0.6
    11   opls_140      1            H5      1       0.06      1.008   ; qtot
-0.54
    12   opls_140      1            H6      1       0.06      1.008   ; qtot
-0.48
    13   opls_140      1            H7      1       0.06      1.008   ; qtot
-0.42
    14   opls_140      1            H8      1       0.06      1.008   ; qtot
-0.36
    15   opls_140      1            H9      1       0.06      1.008   ; qtot
-0.3
    16   opls_140      1           H10      1       0.06      1.008   ; qtot
-0.24
    17   opls_140      1           H11      1       0.06      1.008   ; qtot
-0.18
    18   opls_140      1           H12      1       0.06      1.008   ; qtot
-0.12
    19   opls_140      1           H13      1       0.06      1.008   ; qtot
-0.06
    20   opls_140      1           H14      1       0.06      1.008   ; qtot
0

[ bonds ]
;  ai    aj funct            c0            c1            c2            c3
    1     2     1  1.530000e-01  4.000000e+05  1.530000e-01  4.000000e+05
    1    18     1  1.090000e-01  4.000000e+05  1.090000e-01  4.000000e+05
    1    19     1  1.090000e-01  4.000000e+05  1.090000e-01  4.000000e+05
    1    20     1  1.090000e-01  4.000000e+05  1.090000e-01  4.000000e+05
    2     3     1  1.530000e-01  4.000000e+05  1.530000e-01  4.000000e+05
    2    16     1  1.090000e-01  4.000000e+05  1.090000e-01  4.000000e+05
    2    17     1  1.090000e-01  4.000000e+05  1.090000e-01  4.000000e+05
    3     4     1  1.540000e-01  4.000000e+05  1.540000e-01  4.000000e+05
    3    14     1  1.090000e-01  4.000000e+05  1.090000e-01  4.000000e+05
    3    15     1  1.090000e-01  4.000000e+05  1.090000e-01  4.000000e+05
    4     5     1  1.530000e-01  4.000000e+05  1.530000e-01  4.000000e+05
    4    12     1  1.090000e-01  4.000000e+05  1.090000e-01  4.000000e+05
    4    13     1  1.090000e-01  4.000000e+05  1.090000e-01  4.000000e+05
    5     6     1  1.530000e-01  4.000000e+05  1.530000e-01  4.000000e+05
    5    10     1  1.090000e-01  4.000000e+05  1.090000e-01  4.000000e+05
    5    11     1  1.090000e-01  4.000000e+05  1.090000e-01  4.000000e+05
    6     7     1  1.090000e-01  4.000000e+05  1.090000e-01  4.000000e+05
    6     8     1  1.090000e-01  4.000000e+05  1.090000e-01  4.000000e+05
    6     9     1  1.090000e-01  4.000000e+05  1.090000e-01  4.000000e+05

[ pairs ]
;  ai    aj funct            c0            c1            c2            c3
    1     4     1
    1    14     1
    1    15     1
    2     5     1
    2    12     1
    2    13     1
    3     6     1
    3    10     1
    3    11     1
    3    18     1
    3    19     1
    3    20     1
    4     7     1
    4     8     1
    4     9     1
    4    16     1
    4    17     1
    5    14     1
    5    15     1
    6    12     1
    6    13     1
    7    10     1
    7    11     1
    8    10     1
    8    11     1
    9    10     1
    9    11     1
   10    12     1
   10    13     1
   11    12     1
   11    13     1
   12    14     1
   12    15     1
   13    14     1
   13    15     1
   14    16     1
   14    17     1
   15    16     1
   15    17     1
   16    18     1
   16    19     1
   16    20     1
   17    18     1
   17    19     1
   17    20     1

[ angles ]
;  ai    aj    ak funct            c0            c1            c2
c3
    2     1    18     1  1.120000e+02  4.000000e+02  1.120000e+02
4.000000e+02
    2     1    19     1  1.110000e+02  4.000000e+02  1.110000e+02
4.000000e+02
    2     1    20     1  1.110000e+02  4.000000e+02  1.110000e+02
4.000000e+02
   18     1    19     1  1.070000e+02  4.000000e+02  1.070000e+02
4.000000e+02
   18     1    20     1  1.070000e+02  4.000000e+02  1.070000e+02
4.000000e+02
   19     1    20     1  1.080000e+02  4.000000e+02  1.080000e+02
4.000000e+02
    1     2     3     1  1.130000e+02  4.000000e+02  1.130000e+02
4.000000e+02
    1     2    16     1  1.090000e+02  4.000000e+02  1.090000e+02
4.000000e+02
    1     2    17     1  1.090000e+02  4.000000e+02  1.090000e+02
4.000000e+02
    3     2    16     1  1.100000e+02  4.000000e+02  1.100000e+02
4.000000e+02
    3     2    17     1  1.100000e+02  4.000000e+02  1.100000e+02
4.000000e+02
   16     2    17     1  1.060000e+02  4.000000e+02  1.060000e+02
4.000000e+02
    2     3     4     1  1.130000e+02  4.000000e+02  1.130000e+02
4.000000e+02
    2     3    14     1  1.100000e+02  4.000000e+02  1.100000e+02
4.000000e+02
    2     3    15     1  1.100000e+02  4.000000e+02  1.100000e+02
4.000000e+02
    4     3    14     1  1.090000e+02  4.000000e+02  1.090000e+02
4.000000e+02
    4     3    15     1  1.090000e+02  4.000000e+02  1.090000e+02
4.000000e+02
   14     3    15     1  1.060000e+02  4.000000e+02  1.060000e+02
4.000000e+02
    3     4     5     1  1.130000e+02  4.000000e+02  1.130000e+02
4.000000e+02
    3     4    12     1  1.090000e+02  4.000000e+02  1.090000e+02
4.000000e+02
    3     4    13     1  1.090000e+02  4.000000e+02  1.090000e+02
4.000000e+02
    5     4    12     1  1.100000e+02  4.000000e+02  1.100000e+02
4.000000e+02
    5     4    13     1  1.100000e+02  4.000000e+02  1.100000e+02
4.000000e+02
   12     4    13     1  1.060000e+02  4.000000e+02  1.060000e+02
4.000000e+02
    4     5     6     1  1.130000e+02  4.000000e+02  1.130000e+02
4.000000e+02
    4     5    10     1  1.100000e+02  4.000000e+02  1.100000e+02
4.000000e+02
    4     5    11     1  1.100000e+02  4.000000e+02  1.100000e+02
4.000000e+02
    6     5    10     1  1.090000e+02  4.000000e+02  1.090000e+02
4.000000e+02
    6     5    11     1  1.090000e+02  4.000000e+02  1.090000e+02
4.000000e+02
   10     5    11     1  1.060000e+02  4.000000e+02  1.060000e+02
4.000000e+02
    5     6     7     1  1.110000e+02  4.000000e+02  1.110000e+02
4.000000e+02
    5     6     8     1  1.110000e+02  4.000000e+02  1.110000e+02
4.000000e+02
    5     6     9     1  1.120000e+02  4.000000e+02  1.120000e+02
4.000000e+02
    7     6     8     1  1.080000e+02  4.000000e+02  1.080000e+02
4.000000e+02
    7     6     9     1  1.070000e+02  4.000000e+02  1.070000e+02
4.000000e+02
    8     6     9     1  1.070000e+02  4.000000e+02  1.070000e+02
4.000000e+02

[ dihedrals ]
;  ai    aj    ak    al funct            c0            c1
c2            c3            c4            c5
   18     1     2     3     3  3.600000e+02  5.000000e+00  3.000000e+00
3.600000e+02  5.000000e+00  3.000000e+00
    1     2     3     4     3  3.600000e+02  5.000000e+00  3.000000e+00
3.600000e+02  5.000000e+00  3.000000e+00
    2     3     4     5     3  3.600000e+02  5.000000e+00  3.000000e+00
3.600000e+02  5.000000e+00  3.000000e+00
    3     4     5     6     3  3.600000e+02  5.000000e+00  3.000000e+00
3.600000e+02  5.000000e+00  3.000000e+00
    4     5     6     7     3  3.600000e+02  5.000000e+00  3.000000e+00
3.600000e+02  5.000000e+00  3.000000e+00

[ system ]
; Name
HEX

[ molecules ]
; Compound        #mols
HEX                 256


**************************the first molecule in gro file:(there are 256)

Go Rough, Oppose Many Angry Chinese Serial killers
 5120
    1        C1    1   1.821   1.479   1.500  0.0000  0.0000  0.0000
    1        C2    2   1.688   1.555   1.500  0.0000  0.0000  0.0000
    1        C3    3   1.567   1.462   1.500  0.0000  0.0000  0.0000
    1        C4    4   1.433   1.538   1.500  0.0000  0.0000  0.0000
    1        C5    5   1.312   1.445   1.500  0.0000  0.0000  0.0000
    1        C6    6   1.179   1.521   1.500  0.0000  0.0000  0.0000
    1        H1    7   1.170   1.584   1.412  0.0000  0.0000  0.0000
    1        H2    8   1.170   1.584   1.588  0.0000  0.0000  0.0000
    1        H3    9   1.094   1.453   1.500  0.0000  0.0000  0.0000
    1        H4   10   1.316   1.380   1.587  0.0000  0.0000  0.0000
    1        H5   11   1.316   1.380   1.413  0.0000  0.0000  0.0000
    1        H6   12   1.429   1.603   1.587  0.0000  0.0000  0.0000
    1        H7   13   1.429   1.603   1.413  0.0000  0.0000  0.0000
    1        H8   14   1.571   1.397   1.587  0.0000  0.0000  0.0000
    1        H9   15   1.571   1.397   1.413  0.0000  0.0000  0.0000
    1       H10   16   1.684   1.620   1.587  0.0000  0.0000  0.0000
    1       H11   17   1.684   1.620   1.413  0.0000  0.0000  0.0000
    1       H12   18   1.906   1.547   1.500  0.0000  0.0000  0.0000
    1       H13   19   1.830   1.416   1.412  0.0000  0.0000  0.0000
    1       H14   20   1.830   1.416   1.588  0.0000  0.0000  0.0000
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