[gmx-users] NaN error using mdrun-gpu

Bongkeun Kim bkim at chem.ucsb.edu
Wed Dec 15 08:19:25 CET 2010


Hello,

I got an error log when I used gromacs-gpu on npt simulation.
The error is like:
---------------------------------------------------------------
Input Parameters:
    integrator           = md
    nsteps               = 50000000
    init_step            = 0
    ns_type              = Grid
    nstlist              = 5
    ndelta               = 2
    nstcomm              = 10
    comm_mode            = Linear
    nstlog               = 1000
    nstxout              = 1000
    nstvout              = 1000
    nstfout              = 0
    nstcalcenergy        = 5
    nstenergy            = 1000
    nstxtcout            = 1000
    init_t               = 0
    delta_t              = 0.002
    xtcprec              = 1000
    nkx                  = 32
    nky                  = 32
    nkz                  = 32
    pme_order            = 4
    ewald_rtol           = 1e-05
    ewald_geometry       = 0
    epsilon_surface      = 0
    optimize_fft         = FALSE
    ePBC                 = xyz
    bPeriodicMols        = FALSE
    bContinuation        = TRUE
    bShakeSOR            = FALSE
    etc                  = V-rescale
    nsttcouple           = 5
    epc                  = Parrinello-Rahman
    epctype              = Isotropic
    nstpcouple           = 5
    tau_p                = 2
    ref_p (3x3):
       ref_p[    0]={ 1.00000e+00,  0.00000e+00,  0.00000e+00}
       ref_p[    1]={ 0.00000e+00,  1.00000e+00,  0.00000e+00}
       ref_p[    2]={ 0.00000e+00,  0.00000e+00,  1.00000e+00}
    compress (3x3):
       compress[    0]={ 4.50000e-05,  0.00000e+00,  0.00000e+00}
       compress[    1]={ 0.00000e+00,  4.50000e-05,  0.00000e+00}
       compress[    2]={ 0.00000e+00,  0.00000e+00,  4.50000e-05}
    refcoord_scaling     = No
    posres_com (3):
       posres_com[0]= 0.00000e+00
       posres_com[1]= 0.00000e+00
       posres_com[2]= 0.00000e+00
    posres_comB (3):
       posres_comB[0]= 0.00000e+00
       posres_comB[1]= 0.00000e+00
       posres_comB[2]= 0.00000e+00
    andersen_seed        = 815131
    rlist                = 1
    rlistlong            = 1
    rtpi                 = 0.05
    coulombtype          = PME
    rcoulomb_switch      = 0
    rcoulomb             = 1
    vdwtype              = Cut-off
    rvdw_switch          = 0
    rvdw                 = 1
    epsilon_r            = 1
    epsilon_rf           = 1
    tabext               = 1
    implicit_solvent     = No
    gb_algorithm         = Still
    gb_epsilon_solvent   = 80
    nstgbradii           = 1
    rgbradii             = 1
    gb_saltconc          = 0
    gb_obc_alpha         = 1
    gb_obc_beta          = 0.8
    gb_obc_gamma         = 4.85
    gb_dielectric_offset = 0.009
    sa_algorithm         = Ace-approximation
    sa_surface_tension   = 2.05016
    DispCorr             = EnerPres
    free_energy          = no
    init_lambda          = 0
    delta_lambda         = 0
    n_foreign_lambda     = 0
    sc_alpha             = 0
    sc_power             = 0
    sc_sigma             = 0.3
    sc_sigma_min         = 0.3
    nstdhdl              = 10
    separate_dhdl_file   = yes
    dhdl_derivatives     = yes
    dh_hist_size         = 0
    dh_hist_spacing      = 0.1
    nwall                = 0
    wall_type            = 9-3
    wall_atomtype[0]     = -1
    wall_atomtype[1]     = -1
    wall_density[0]      = 0
    wall_density[1]      = 0
    wall_ewald_zfac      = 3
    pull                 = no
    disre                = No
    disre_weighting      = Conservative
    disre_mixed          = FALSE
    dr_fc                = 1000
    dr_tau               = 0
    nstdisreout          = 100
    orires_fc            = 0
    orires_tau           = 0
    nstorireout          = 100
    dihre-fc             = 1000
    em_stepsize          = 0.01
    em_tol               = 10
    niter                = 20
    fc_stepsize          = 0
    nstcgsteep           = 1000
    nbfgscorr            = 10
    ConstAlg             = Lincs
    shake_tol            = 0.0001
    lincs_order          = 4
    lincs_warnangle      = 30
    lincs_iter           = 1
    bd_fric              = 0
    ld_seed              = 1993
    cos_accel            = 0
    deform (3x3):
       deform[    0]={ 0.00000e+00,  0.00000e+00,  0.00000e+00}
       deform[    1]={ 0.00000e+00,  0.00000e+00,  0.00000e+00}
       deform[    2]={ 0.00000e+00,  0.00000e+00,  0.00000e+00}
    userint1             = 0
    userint2             = 0
    userint3             = 0
    userint4             = 0
    userreal1            = 0
    userreal2            = 0
    userreal3            = 0
    userreal4            = 0
grpopts:
    nrdf:       24715
    ref_t:         325
    tau_t:         0.1
anneal:          No
ann_npoints:           0
    acc:            0           0           0
    nfreeze:           N           N           N
    energygrp_flags[  0]: 0
    efield-x:
       n = 0
    efield-xt:
       n = 0
    efield-y:
       n = 0
    efield-yt:
       n = 0
    efield-z:
       n = 0
    efield-zt:
       n = 0
    bQMMM                = FALSE
    QMconstraints        = 0
    QMMMscheme           = 0
    scalefactor          = 1
qm_opts:
    ngQM                 = 0
Table routines are used for coulomb: TRUE
Table routines are used for vdw:     FALSE
Will do PME sum in reciprocal space.

++++ PLEASE READ AND CITE THE FOLLOWING REFERENCE ++++
U. Essman, L. Perela, M. L. Berkowitz, T. Darden, H. Lee and L. G. Pedersen
A smooth particle mesh Ewald method
J. Chem. Phys. 103 (1995) pp. 8577-8592
-------- -------- --- Thank You --- -------- --------

Will do ordinary reciprocal space Ewald sum.
Using a Gaussian width (1/beta) of 0.320163 nm for Ewald
Cut-off's:   NS: 1   Coulomb: 1   LJ: 1
Long Range LJ corr.: <C6> 2.9723e-04
System total charge: 0.000
Generated table with 1000 data points for Ewald.
Tabscale = 500 points/nm
Generated table with 1000 data points for LJ6.
Tabscale = 500 points/nm
Generated table with 1000 data points for LJ12.
Tabscale = 500 points/nm
Generated table with 1000 data points for 1-4 COUL.
Tabscale = 500 points/nm
Generated table with 1000 data points for 1-4 LJ6.
Tabscale = 500 points/nm
Generated table with 1000 data points for 1-4 LJ12.
Tabscale = 500 points/nm

Enabling SPC-like water optimization for 3910 molecules.

Configuring nonbonded kernels...
Configuring standard C nonbonded kernels...



Initializing LINear Constraint Solver

++++ PLEASE READ AND CITE THE FOLLOWING REFERENCE ++++
B. Hess and H. Bekker and H. J. C. Berendsen and J. G. E. M. Fraaije
LINCS: A Linear Constraint Solver for molecular simulations
J. Comp. Chem. 18 (1997) pp. 1463-1472
-------- -------- --- Thank You --- -------- --------

The number of constraints is 626

++++ PLEASE READ AND CITE THE FOLLOWING REFERENCE ++++
S. Miyamoto and P. A. Kollman
SETTLE: An Analytical Version of the SHAKE and RATTLE Algorithms for Rigid
Water Models
J. Comp. Chem. 13 (1992) pp. 952-962
-------- -------- --- Thank You --- -------- --------

Center of mass motion removal mode is Linear
We have the following groups for center of mass motion removal:
   0:  rest

++++ PLEASE READ AND CITE THE FOLLOWING REFERENCE ++++
G. Bussi, D. Donadio and M. Parrinello
Canonical sampling through velocity rescaling
J. Chem. Phys. 126 (2007) pp. 014101
-------- -------- --- Thank You --- -------- --------

Max number of connections per atom is 103
Total number of connections is 37894
Max number of graph edges per atom is 4
Total number of graph edges is 16892

OpenMM plugins loaded from directory /home/bkim/packages/openmm/lib/plugins:
libOpenMMCuda.so, libOpenMMOpenCL.so,
The combination rule of the used force field matches the one used by OpenMM.
Gromacs will use the OpenMM platform: Cuda
Non-supported GPU selected (#1, Tesla T10 Processor), forced  
continuing.Note, th
at the simulation can be slow or it migth even crash.
Pre-simulation ~15s memtest in progress...
Memory test completed without errors.

++++ PLEASE READ AND CITE THE FOLLOWING REFERENCE ++++
Entry Friedrichs2009 not found in citation database
-------- -------- --- Thank You --- -------- --------

Initial temperature: 0 K

Started mdrun on node 0 Tue Dec 14 23:10:20 2010

            Step           Time         Lambda
               0        0.00000        0.00000

    Energies (kJ/mol)
       Potential    Kinetic En.   Total Energy    Temperature   Constr. rmsd
    -1.40587e+05    3.36048e+04   -1.06982e+05    3.27065e+02    0.00000e+00

            Step           Time         Lambda
            1000        2.00000        0.00000

    Energies (kJ/mol)
       Potential    Kinetic En.   Total Energy    Temperature   Constr. rmsd
             nan            nan            nan            nan    0.00000e+00



Received the second INT/TERM signal, stopping at the next step

            Step           Time         Lambda
            1927        3.85400        0.00000

    Energies (kJ/mol)
       Potential    Kinetic En.   Total Energy    Temperature   Constr. rmsd
             nan            nan            nan            nan    0.00000e+00

Writing checkpoint, step 1927 at Tue Dec 14 23:12:07 2010


         <======  ###############  ==>
         <====  A V E R A G E S  ====>
         <==  ###############  ======>

         Statistics over 3 steps using 3 frames

    Energies (kJ/mol)
       Potential    Kinetic En.   Total Energy    Temperature   Constr. rmsd
             nan            nan            nan            nan    0.00000e+00

           Box-X          Box-Y          Box-Z
     3.91363e-24    6.72623e-44   -1.71925e+16

    Total Virial (kJ/mol)
     0.00000e+00    0.00000e+00    0.00000e+00
     0.00000e+00    0.00000e+00    0.00000e+00
     0.00000e+00    0.00000e+00    0.00000e+00

    Pressure (bar)
     0.00000e+00    0.00000e+00    0.00000e+00
     0.00000e+00    0.00000e+00    0.00000e+00
     0.00000e+00    0.00000e+00    0.00000e+00

    Total Dipole (D)
     0.00000e+00    0.00000e+00    0.00000e+00
------------------------------------------------------------------------

The input mdp file is given by
========================================================
title           = OPLS Lysozyme MD
; Run parameters
integrator      = md            ; leap-frog integrator
nsteps          = 50000000      ;
dt              = 0.002         ; 2 fs
; Output control
nstxout         = 1000          ; save coordinates every 2 ps
nstvout         = 1000          ; save velocities every 2 ps
nstxtcout       = 1000          ; xtc compressed trajectory output every 2 ps
nstenergy       = 1000          ; save energies every 2 ps
nstlog          = 1000          ; update log file every 2 ps
; Bond parameters
continuation    = yes           ; Restarting after NPT
constraint_algorithm = lincs    ; holonomic constraints
constraints     = all-bonds     ; all bonds (even heavy atom-H bonds)  
constraine
d
lincs_iter      = 1             ; accuracy of LINCS
lincs_order     = 4             ; also related to accuracy
; Neighborsearching
ns_type         = grid          ; search neighboring grid cels
nstlist         = 5             ; 10 fs
rlist           = 1.0           ; short-range neighborlist cutoff (in nm)
rcoulomb        = 1.0           ; short-range electrostatic cutoff (in nm)
rvdw            = 1.0           ; short-range van der Waals cutoff (in nm)
; Electrostatics
coulombtype     = PME           ; Particle Mesh Ewald for long-range  
electrostat
ics
pme_order       = 4             ; cubic interpolation
fourierspacing  = 0.16          ; grid spacing for FFT
; Temperature coupling is on
tcoupl          = V-rescale     ; modified Berendsen thermostat
tc-grps         = System        ; two coupling groups - more accurate
tau_t           = 0.1           ; time constant, in ps
ref_t           = 325           ; reference temperature, one for each  
group, in
K
; Pressure coupling is on
pcoupl          = Parrinello-Rahman     ; Pressure coupling on in NPT
pcoupltype      = isotropic     ; uniform scaling of box vectors
tau_p           = 2.0           ; time constant, in ps
ref_p           = 1.0           ; reference pressure, in bar
compressibility = 4.5e-5        ; isothermal compressibility of water, bar^-1
; Periodic boundary conditions
pbc             = xyz           ; 3-D PBC
; Dispersion correction
DispCorr        = EnerPres      ; account for cut-off vdW scheme
; Velocity generation
gen_vel         = no            ; Velocity generation is off
=========================================================================

It worked with generic cpu mdrun but gave this error when mdrun-gpu  
was used by

mdrun-gpu -deffnm md_0_2 -device  
"OpenMM:platform=Cuda,deviceid=1,force-device=y
es"

If you have any idea how to avoid this problem, I will really appreciate it.
Thank you.
Bongkeun Kim





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