[gmx-users] Re: gmx-users Digest, Vol 79, Issue 89

sa sagmx.mail at gmail.com
Fri Nov 12 20:17:10 CET 2010


>
>
> sa wrote:
> >
> >     On 13/11/2010 4:07 AM, sa wrote:
> >      > Dear All,
> >      >
> >      > I would like to compute the average 2D density distribution of the
> >      > water around 6 peptides aggregated in the cluster within the
> >      > simulation box with gromacs, for that I think that g_densmap is
> the
> >      > the good tool (correct ?).
> >      >
> >      > However it is not very clear for how to use g_densmap. Below the
> >      > command I used with g_densmap (ver GMX 4.5.3)
> >      >
> >      > g_densmap_mpi -f ./TRAJ/XTC/6_Pep_Urea_Pref_All.xtc -s
> >      > ./TRAJ/TPR/em.tpr  -bin 0.02 -amax 30 -rmax 30 -b 0 -e 80000 -o
> >      > 6_Peptide_53A6_densmap.xpm -od 6_Peptide_53A6_densmap.dat
> >      >
> >      > When I use the above command, g_densmap asks me to choose two
> groups
> >      > to define the axis and an analysis group:
> >      >
> >      > Reading file ./TRAJ/TPR/em.tpr, VERSION 4.5.1 (single precision)
> >      > Reading file ./TRAJ/TPR/em.tpr, VERSION 4.5.1 (single precision)
> >      > Select two groups to define the axis and an analysis group
> >      > Group     0 (         System) has 86359 elements
> >      > Group     1 (        Protein) has   546 elements
> >      > Group     2 (      Protein-H) has   396 elements
> >      > Group     3 (        C-alpha) has    48 elements
> >      > Group     4 (       Backbone) has   144 elements
> >      > Group     5 (      MainChain) has   192 elements
> >      > Group     6 (   MainChain+Cb) has   234 elements
> >      > Group     7 (    MainChain+H) has   246 elements
> >      > Group     8 (      SideChain) has   300 elements
> >      > Group     9 (    SideChain-H) has   204 elements
> >      > Group    10 (    Prot-Masses) has   546 elements
> >      > Group    11 (    non-Protein) has 85813 elements
> >      > Group    12 (          Other) has 17320 elements
> >      > Group    13 (            URE) has 17320 elements
> >      > Group    14 (             CL) has     6 elements
> >      > Group    15 (          Water) has 68487 elements
> >      > Group    16 (            SOL) has 68487 elements
> >      > Group    17 (      non-Water) has 17872 elements
> >      > Group    18 (            Ion) has     6 elements
> >      > Group    19 (            URE) has 17320 elements
> >      > Group    20 (             CL) has     6 elements
> >      > Group    21 ( Water_and_ions) has 68493 elements
> >      > Select a group: 1
> >      > Selected 1: 'Protein'
> >      > Select a group: 16
> >      > Selected 16: 'SOL'
> >      > Select a group: 16
> >      > Selected 16: 'SOL'
> >      >
> >      > I chose protein and SOL, the program ask me to choose a third
> group
> >      > (?) What to choose ?
> >
> >     Doesn't g_densmap -h explain the three groups?
> >
> >
> >  Yes I have read the help of the tool but it is not clear to me why i
> > have to choose three groups since i want to compute the water density
> > map around my peptides (-> two groups)
> >
> >
>
> The first two groups determine the axis.  Per g_densmap -h:
>
> "Three groups should be supplied, the centers of mass of the first two
> groups define the axis, the third defines the analysis group."
>
> I suspect the fact that you've chosen "SOL" for the second group might be
> causing problems (since, presumably, you have water all around), but I have
> never used g_densmap, so I don't know for sure.
>
> -Justin
>

Ok I will try and play with the different groups of my system to see if it
works...

Stefane


>
> >      > I choose SOL again, the program computes something but i can not
> >      > inspect the results are what i want since no xpm is generated by
> >      > g_densmap (is this a bug ?)
> >
> >     Probably badly-formed input is silently breaking something somewhere.
> >
> >
> > I don't understand your response since with the above command and -o
> > argument show that an xpm with the name "6_Peptide_53A6_densmap.xpm"
> > should appear
> >
> >
> >                          :-)  G  R  O  M  A  C  S  (-:
> >
> >                      Gnomes, ROck Monsters And Chili Sauce
> >
> >                             :-)  VERSION 4.5.3  (-:
> >
> >         Written by Emile Apol, Rossen Apostolov, Herman J.C. Berendsen,
> >       Aldert van Buuren, Pär Bjelkmar, Rudi van Drunen, Anton Feenstra,
> >         Gerrit Groenhof, Peter Kasson, Per Larsson, Pieter Meulenhoff,
> >            Teemu Murtola, Szilard Pall, Sander Pronk, Roland Schulz,
> >                 Michael Shirts, Alfons Sijbers, Peter Tieleman,
> >
> >                Berk Hess, David van der Spoel, and Erik Lindahl.
> >
> >        Copyright (c) 1991-2000, University of Groningen, The Netherlands.
> >             Copyright (c) 2001-2010, The GROMACS development team at
> >         Uppsala University & The Royal Institute of Technology, Sweden.
> >             check out http://www.gromacs.org for more information.
> >
> >          This program is free software; you can redistribute it and/or
> >           modify it under the terms of the GNU General Public License
> >          as published by the Free Software Foundation; either version 2
> >              of the License, or (at your option) any later version.
> >
> >            :-)  /work/taulier01/gromacs-4.5.3/bin/g_densmap_mpi  (-:
> >
> > Option     Filename  Type         Description
> > ------------------------------------------------------------
> >   -f ./TRAJ/XTC/6_Pep_Urea_Pref_All.xtc  Input        Trajectory: xtc
> > trr trj
> >                                    gro g96 pdb cpt
> >   -s ./TRAJ/TPR/em.tpr  Input, Opt!  Structure+mass(db): tpr tpb tpa gro
> g96
> >                                    pdb
> >   -n      index.ndx  Input, Opt.  Index file
> >  -od 6_Peptide_53A6_densmap.dat  Output, Opt! Generic data file
> >   -o 6_Peptide_53A6_densmap.xpm  Output       X PixMap compatible matrix
> > file
> >
> >
> > Stefane
> >
> >
> >
> >     Mark
> >
> >
> >
> >
> >
>
> --
> ========================================
>
> Justin A. Lemkul
> Ph.D. Candidate
> ICTAS Doctoral Scholar
> MILES-IGERT Trainee
> Department of Biochemistry
> Virginia Tech
> Blacksburg, VA
> jalemkul[at]vt.edu | (540) 231-9080
> http://www.bevanlab.biochem.vt.edu/Pages/Personal/justin
>
> ========================================
>
>
>
>
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