[gmx-users] output force

Петр Попов magistrpetrus at gmail.com
Sun Oct 10 19:38:39 CEST 2010


And what if I have four helices in Protein and a,b,c,d group for each helix
in index.file and I want to get a-c pmf?


10 октября 2010 г. 21:20 пользователь Justin A. Lemkul <jalemkul at vt.edu>написал:

>
>
> Justin A. Lemkul wrote:
>
>>
>>
>> Петр Попов wrote:
>>
>>> Unfortunately I've got an error.
>>>
>>> This is .mdp file:
>>>
>>> title = title
>>> cpp                 =  /lib/cpp
>>> integrator          =  md
>>> tinit               =  0.0
>>> dt                  =  0.002 nsteps              =  25000 nstcomm
>>>     =  1
>>> comm_grps           =  System
>>> ld_seed             =  -1
>>> niter               =  40
>>> nstxout             =  10000
>>> nstvout             =  0
>>> nstfout             =  0
>>> nstlog              =  500
>>> nstenergy           =  100
>>> nstlist             =  10
>>>
>>
> If this .mdp file is to be used for a rerun, please recall the advice I
> gave you earlier about the proper setting for nstlist.
>
> -Justin
>
>
>  ns_type             =  grid
>>> rlist               =  1.2
>>> coulombtype         =  PME
>>> rcoulomb            =  1.2
>>> fourierspacing      =  0.12
>>> pme_order           =  4
>>> optimize_fft        =  yes
>>> pbc                 =  xyz
>>> vdwtype             =  Cut-off
>>> rvdw                =  1.2
>>> tcoupl              =  V-rescale
>>> tc_grps             =  System
>>> tau_t               =  0.1
>>> ref_t               =  300.0
>>> annealing           = single
>>> annealing_npoints   = 3
>>> annealing_time      = 0 5 50
>>> annealing_temp      = 5 300 300
>>> pcoupl              =  berendsen
>>> pcoupltype          =  isotropic
>>> compressibility     =  4.5e-5
>>> tau_p               =  10.0
>>> ref_p               =  1.0
>>> gen_vel             =  yes
>>> gen_temp            =  5.0
>>> gen_seed            =  -1
>>> constraints         =  all-bonds
>>> constraint_algorithm      =  Lincs
>>> lincs_order         =  4
>>> disre               =  simple
>>> disre_weighting     = conservative
>>> disre_mixed         = no
>>> nstdisreout         = 50000
>>> disre_tau           = 0
>>> pull                = constraint
>>> pull_geometry       = distance
>>> pull_dim            = Y Y Y
>>> pull_constr_tol     = 1e-6
>>> pull_nstfout        = 1
>>> pull_nstxout        = 1
>>> pull_ngroups        = 1
>>> pull_group0         = a
>>> pull_group1         = b
>>> pull_init1          = 0.700
>>> pull_start          = no
>>> pull_k1             = 1000
>>> lincs_iter          = 2
>>> energygrps          = Protein Protein
>>>
>>> I just replace in .mdp file line energygrps = System and the error is:
>>>
>>> Fatal error:
>>> Atom 1 in multiple Energy Mon. groups (1 and 2)
>>>
>>> What should I do to avoid this?
>>>
>>>
>> You cannot use multiple energygrps if those groups overlap in any way, as
>> the error indicates.  I thought you were setting "energygrps = Protein SOL"?
>>  If you're trying to get protein-only terms, then just set "energygrps =
>> Protein"
>>
>> -Justin
>>
>>
>>>
>>> 10 октября 2010 г. 20:01 пользователь Петр Попов <
>>> magistrpetrus at gmail.com <mailto:magistrpetrus at gmail.com>> написал:
>>>
>>>    Thank you very much!
>>>
>>>    10 октября 2010 г. 19:58 пользователь Justin A. Lemkul
>>>    <jalemkul at vt.edu <mailto:jalemkul at vt.edu>> написал:
>>>
>>>
>>>
>>>        Петр Попов wrote:
>>>
>>>            So if I want to get protein-solvent component I should add
>>>            in .mdp:
>>>
>>>            energygrps = Protein SOL
>>>
>>>            ?
>>>
>>>
>>>        Yes, and set nstlist = 1.
>>>
>>>        -Justin
>>>
>>>            10 октября 2010 г. 16:41 пользователь Justin A. Lemkul
>>>            <jalemkul at vt.edu <mailto:jalemkul at vt.edu>
>>>            <mailto:jalemkul at vt.edu <mailto:jalemkul at vt.edu>>> написал:
>>>
>>>
>>>
>>>
>>>               Петр Попов wrote:
>>>
>>>                   Thank you for response!
>>>                   One more question:
>>>                   How can I get file with energy groups? Should I use
>>>            grompp with
>>>                   a -e ener.edr option? In this case, how to build
>>>            ener.edr file?
>>>
>>>
>>>               The "energrygrps" keyword is an .mdp option, so generate
>>>            a new .tpr
>>>               file with the desired groups and use the -rerun feature
>>>            of mdrun on
>>>               the trajectory that has already been produced.
>>>
>>>               -Justin
>>>
>>>                   9 октября 2010 г. 14:50 пользователь Mark Abraham
>>>                   <mark.abraham at anu.edu.au
>>>            <mailto:mark.abraham at anu.edu.au>
>>>            <mailto:mark.abraham at anu.edu.au
>>>            <mailto:mark.abraham at anu.edu.au>>
>>>                   <mailto:mark.abraham at anu.edu.au
>>>            <mailto:mark.abraham at anu.edu.au>
>>>                   <mailto:mark.abraham at anu.edu.au
>>>            <mailto:mark.abraham at anu.edu.au>>>> написал:
>>>
>>>
>>>                      You can get that with cunning use of energy groups
>>>            and mdrun
>>>                   -rerun,
>>>                      but not mid-simulation.
>>>                      Mark
>>>
>>>                      ----- Original Message -----
>>>                      From: Петр Попов <magistrpetrus at gmail.com
>>>            <mailto:magistrpetrus at gmail.com>
>>>                   <mailto:magistrpetrus at gmail.com
>>>            <mailto:magistrpetrus at gmail.com>>
>>>                      <mailto:magistrpetrus at gmail.com
>>>            <mailto:magistrpetrus at gmail.com>
>>>                   <mailto:magistrpetrus at gmail.com
>>>            <mailto:magistrpetrus at gmail.com>>>>
>>>                      Date: Saturday, October 9, 2010 21:41
>>>                      Subject: [gmx-users] output force
>>>                      To: gmx-users at gromacs.org
>>>            <mailto:gmx-users at gromacs.org> <mailto:gmx-users at gromacs.org
>>>            <mailto:gmx-users at gromacs.org>>
>>>                   <mailto:gmx-users at gromacs.org
>>>            <mailto:gmx-users at gromacs.org> <mailto:gmx-users at gromacs.org
>>>            <mailto:gmx-users at gromacs.org>>>
>>>
>>>                       > Hello dear gmx-users!
>>>                       >
>>>                       > When calculated forces in gromacs to produce
>>>            pmf, we have
>>>                   the net
>>>                      force in output. For example:
>>>                       > ...
>>>                       > #
>>>                       > # Giving Russians Opium May Alter Current
>>> Situation
>>>                       > #
>>>                       > @    title "Pull force"
>>>                       > @    xaxis  label "Time (ps)"
>>>                       > @    yaxis  label "Force (kJ/mol/nm)"
>>>                       > @TYPE xy
>>>                       > 0.000000                1017490.761270
>>>                       > 0.002000                -253098.034916
>>>                       > 0.004000                -43856.400160
>>>                       > 0.006000                48980.619113
>>>                       > 0.008000                52103.053067
>>>                       > 0.010000                33788.090031
>>>                       > 0.012000                19096.388350
>>>                       > 0.014000                14094.738810
>>>                       > 0.016000                14027.621966
>>>                       > 0.018000                15162.993741
>>>                       > 0.020000                14136.978177
>>>                       > ... etc.
>>>                       >
>>>                       > What sould I do to get the net force of
>>>            protein-solvent
>>>                      interactions or protein-protein interactions or
>>>            solvent-solvent
>>>                      interactions instead and get output .xvg file in
>>>            the form
>>>                   like this:
>>>                       >
>>>                       > time     Force(type1)    Force(type2)
>>>   Force(type3)
>>>                       >
>>>                       > t1         f1                   f1
>>>                 f1
>>>                       > t2         f2                   f2
>>>                 f2
>>>                       > t3         f3                   f3
>>>                 f3
>>>                       > ...        ...                   ...
>>>                   ...
>>>                       > etc.
>>>                       >
>>>                       > Thank you for attention and I hope you will
>>>            help me!
>>>                       > --
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>>>               --     ========================================
>>>
>>>               Justin A. Lemkul
>>>               Ph.D. Candidate
>>>               ICTAS Doctoral Scholar
>>>               MILES-IGERT Trainee
>>>               Department of Biochemistry
>>>               Virginia Tech
>>>               Blacksburg, VA
>>>               jalemkul[at]vt.edu <http://vt.edu> <http://vt.edu> |
>>>            (540) 231-9080
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>>>               http://www.bevanlab.biochem.vt.edu/Pages/Personal/justin
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>>>        --         ========================================
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>>>        Justin A. Lemkul
>>>        Ph.D. Candidate
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>>>        Department of Biochemistry
>>>        Virginia Tech
>>>        Blacksburg, VA
>>>        jalemkul[at]vt.edu <http://vt.edu> | (540) 231-9080
>>>        http://www.bevanlab.biochem.vt.edu/Pages/Personal/justin
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>>
> --
> ========================================
>
> Justin A. Lemkul
> Ph.D. Candidate
> ICTAS Doctoral Scholar
> MILES-IGERT Trainee
> Department of Biochemistry
> Virginia Tech
> Blacksburg, VA
> jalemkul[at]vt.edu | (540) 231-9080
> http://www.bevanlab.biochem.vt.edu/Pages/Personal/justin
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