[gmx-users] output force

Петр Попов magistrpetrus at gmail.com
Mon Oct 11 18:04:40 CEST 2010


Hello dear gmx-users!

So, I run md and got all files md.cpt, .trr, .gro, mdf.xvg,... etc.
then I did: grompp_d -f sp.mdp -c md.gro -n index.ndx -p topol.top -o sp.tpr
where sp.mdp differ from md.mdp in one line: energygrps = Protein SOL (in
md.mdp: energygrps = System)
after that I did: mdrun_d -s sp.tpr -pf spf -rerun md.trr
and got file spf.xvg, but there was no forces:

@    title "Pull force"
@    xaxis  label "Time (ps)"
@    yaxis  label "Force (kJ/mol/nm)"
@TYPE xy
0.000000                0.000000
20.000000               0.000000
40.000000               0.000000
60.000000               0.000000
80.000000               0.000000
100.000000              0.000000
120.000000              0.000000
140.000000              0.000000
160.000000              0.000000
180.000000              0.000000
200.000000              0.000000

Also while reading frame I had a warning:

 WARNING: Some frames do not contain velocities.
         Ekin, temperature and pressure are incorrect,
         the virial will be incorrect when constraints are present.

But I have no idea how to fix this.

Help me, please.

Sincerely.
Petr.



11 октября 2010 г. 6:33 пользователь Dallas Warren <Dallas.Warren at monash.edu
> написал:

>  The error has told you, you have repeat energy groups, where at least one
> (and in your case all) of the atoms are placed within two energy groups.
>
>
>
> Solution, define your energy groups so that you don't have atoms in more
> than one.
>
>
>
> You currently have:
>
> energygrps          = Protein Protein
>
>
>
> Should be something like
>
> energygrps          = Protein SOL
>
>
>
> Catch ya,
>
> Dr. Dallas Warren
>
> Medicinal Chemistry and Drug Action
>
> Monash Institute of Pharmaceutical Sciences, Monash University
> 381 Royal Parade, Parkville VIC 3010
> dallas.warren at monash.edu
>
> +61 3 9903 9304
> ---------------------------------
> When the only tool you own is a hammer, every problem begins to resemble a
> nail.
>
>
>
> *From:* gmx-users-bounces at gromacs.org [mailto:
> gmx-users-bounces at gromacs.org] *On Behalf Of *???? ?????
> *Sent:* Monday, 11 October 2010 4:13 AM
> *To:* jalemkul at vt.edu; Discussion list for GROMACS users
> *Subject:* Re: [gmx-users] output force
>
>
>
> Unfortunately I've got an error.
>
> This is .mdp file:
>
> title = title
> cpp                 =  /lib/cpp
> integrator          =  md
> tinit               =  0.0
> dt                  =  0.002
> nsteps              =  25000
> nstcomm             =  1
> comm_grps           =  System
> ld_seed             =  -1
> niter               =  40
> nstxout             =  10000
> nstvout             =  0
> nstfout             =  0
> nstlog              =  500
> nstenergy           =  100
> nstlist             =  10
> ns_type             =  grid
> rlist               =  1.2
> coulombtype         =  PME
> rcoulomb            =  1.2
> fourierspacing      =  0.12
> pme_order           =  4
> optimize_fft        =  yes
> pbc                 =  xyz
> vdwtype             =  Cut-off
> rvdw                =  1.2
> tcoupl              =  V-rescale
> tc_grps             =  System
> tau_t               =  0.1
> ref_t               =  300.0
> annealing           = single
> annealing_npoints   = 3
> annealing_time      = 0 5 50
> annealing_temp      = 5 300 300
> pcoupl              =  berendsen
> pcoupltype          =  isotropic
> compressibility     =  4.5e-5
> tau_p               =  10.0
> ref_p               =  1.0
> gen_vel             =  yes
> gen_temp            =  5.0
> gen_seed            =  -1
> constraints         =  all-bonds
> constraint_algorithm      =  Lincs
> lincs_order         =  4
> disre               =  simple
> disre_weighting     = conservative
> disre_mixed         = no
> nstdisreout         = 50000
> disre_tau           = 0
> pull                = constraint
> pull_geometry       = distance
> pull_dim            = Y Y Y
> pull_constr_tol     = 1e-6
> pull_nstfout        = 1
> pull_nstxout        = 1
> pull_ngroups        = 1
> pull_group0         = a
> pull_group1         = b
> pull_init1          = 0.700
> pull_start          = no
> pull_k1             = 1000
> lincs_iter          = 2
> energygrps          = Protein Protein
>
> I just replace in .mdp file line energygrps = System and the error is:
>
> Fatal error:
> Atom 1 in multiple Energy Mon. groups (1 and 2)
>
> What should I do to avoid this?
>
>
>  10 октября 2010 г. 20:01 пользователь Петр Попов <magistrpetrus at gmail.com>
> написал:
>
> Thank you very much!
>
> 10 октября 2010 г. 19:58 пользователь Justin A. Lemkul <jalemkul at vt.edu>
> написал:
>
>
>
>
>
> Петр Попов wrote:
>
> So if I want to get protein-solvent component I should add in .mdp:
>
> energygrps = Protein SOL
>
> ?
>
>
>
> Yes, and set nstlist = 1.
>
> -Justin
>
> 10 октября 2010 г. 16:41 пользователь Justin A. Lemkul <jalemkul at vt.edu<mailto:
> jalemkul at vt.edu>> написал:
>
>
>
>
>
>    Петр Попов wrote:
>
>        Thank you for response!
>        One more question:
>        How can I get file with energy groups? Should I use grompp with
>        a -e ener.edr option? In this case, how to build ener.edr file?
>
>
>    The "energrygrps" keyword is an .mdp option, so generate a new .tpr
>    file with the desired groups and use the -rerun feature of mdrun on
>    the trajectory that has already been produced.
>
>    -Justin
>
>        9 октября 2010 г. 14:50 пользователь Mark Abraham
>        <mark.abraham at anu.edu.au <mailto:mark.abraham at anu.edu.au>
>        <mailto:mark.abraham at anu.edu.au
>        <mailto:mark.abraham at anu.edu.au>>> написал:
>
>
>           You can get that with cunning use of energy groups and mdrun
>        -rerun,
>           but not mid-simulation.
>           Mark
>
>           ----- Original Message -----
>           From: Петр Попов <magistrpetrus at gmail.com
>        <mailto:magistrpetrus at gmail.com>
>
>           <mailto:magistrpetrus at gmail.com
>        <mailto:magistrpetrus at gmail.com>>>
>           Date: Saturday, October 9, 2010 21:41
>           Subject: [gmx-users] output force
>           To: gmx-users at gromacs.org <mailto:gmx-users at gromacs.org>
>
>        <mailto:gmx-users at gromacs.org <mailto:gmx-users at gromacs.org>>
>
>            > Hello dear gmx-users!
>            >
>            > When calculated forces in gromacs to produce pmf, we have
>        the net
>           force in output. For example:
>            > ...
>            > #
>            > # Giving Russians Opium May Alter Current Situation
>            > #
>            > @    title "Pull force"
>            > @    xaxis  label "Time (ps)"
>            > @    yaxis  label "Force (kJ/mol/nm)"
>            > @TYPE xy
>            > 0.000000                1017490.761270
>            > 0.002000                -253098.034916
>            > 0.004000                -43856.400160
>            > 0.006000                48980.619113
>            > 0.008000                52103.053067
>            > 0.010000                33788.090031
>            > 0.012000                19096.388350
>            > 0.014000                14094.738810
>            > 0.016000                14027.621966
>            > 0.018000                15162.993741
>            > 0.020000                14136.978177
>            > ... etc.
>            >
>            > What sould I do to get the net force of protein-solvent
>           interactions or protein-protein interactions or solvent-solvent
>           interactions instead and get output .xvg file in the form
>        like this:
>            >
>            > time     Force(type1)    Force(type2)    Force(type3)
>            >
>            > t1         f1                   f1                    f1
>            > t2         f2                   f2                    f2
>            > t3         f3                   f3                    f3
>            > ...        ...                   ...                    ...
>            > etc.
>            >
>            > Thank you for attention and I hope you will help me!
>            > --
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>    --     ========================================
>
>    Justin A. Lemkul
>    Ph.D. Candidate
>    ICTAS Doctoral Scholar
>    MILES-IGERT Trainee
>    Department of Biochemistry
>    Virginia Tech
>    Blacksburg, VA
>
>    jalemkul[at]vt.edu <http://vt.edu> | (540) 231-9080
>
>
>    http://www.bevanlab.biochem.vt.edu/Pages/Personal/justin
>
>    ========================================
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> --
> ========================================
>
> Justin A. Lemkul
> Ph.D. Candidate
> ICTAS Doctoral Scholar
> MILES-IGERT Trainee
> Department of Biochemistry
> Virginia Tech
> Blacksburg, VA
> jalemkul[at]vt.edu | (540) 231-9080
> http://www.bevanlab.biochem.vt.edu/Pages/Personal/justin
>
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