[gmx-users] how to simulate crystals in Gromacs

ZHANG Lu lyizl at ust.hk
Thu Apr 7 08:21:29 CEST 2011


Thank you for your answer.
Could you give me some advice on the size of cell box? What is the proper
size if I want to do MD simulation in crystal environment?
I didn't change the cell size when I convert cif file to pdb file; in
other word, I didn't use editconf to produce the cell box. What I did was
just :
pdb2gmx -> genconf ( -nbox 10 10 10 -dist 0.5 0.5 0.5 ) -> genbox. Was it
wrong?

Below is the coordination and cell box after I run pdb2gmx. I use water to
fill in the box after genconf.

    1CLC    OBD    1  -0.042   0.476   0.219
    1CLC    O1D    2  -0.298   0.731   0.310
    1CLC    O2D    3  -0.163   0.650   0.469
    1CLC    O1A    4  -0.697   0.691   0.093
    1CLC    O2A    5  -0.822   0.826   0.214
    1CLC    CMB    6  -0.877   0.164   0.937
    1CLC    CAB    7  -0.708  -0.089   1.050
    1CLC    CBB    8  -0.820  -0.108   1.104
    1CLC    CMC    9  -0.224  -0.302   0.948
    1CLC    CAC   10   0.016  -0.236   0.743
    1CLC    CBC   11   0.014  -0.333   0.627
    1CLC    CMD   12   0.106   0.164   0.377
    1CLC    CAD   13  -0.122   0.426   0.298
    1CLC    CBD   14  -0.260   0.494   0.322
    1CLC    CAA   15  -0.598   0.558   0.332
    1CLC    CBA   16  -0.685   0.684   0.330
    1CLC    CMA   17  -0.672   0.604   0.686
    1CLC    CGD   18  -0.246   0.640   0.366
    1CLC    CED   19  -0.149   0.789   0.509
    1CLC    CGA   20  -0.733   0.732   0.198
    1CLC     C1   21  -0.878   0.885   0.095
    1CLC    CMG   22  -0.373   0.175   0.683
    1CLC     NB   23  -0.540   0.110   0.783
    1CLC     NC   24  -0.278  -0.005   0.729
    1CLC     ND   25  -0.234   0.194   0.534
    1CLC     NA   26  -0.492   0.328   0.583
    1CLC    C1B   27  -0.657   0.181   0.798
    1CLC    C2B   28  -0.741   0.114   0.897
    1CLC    C3B   29  -0.670   0.008   0.944
    1CLC    C4B   30  -0.543   0.006   0.871
    1CLC    CHC   31  -0.442  -0.086   0.890
    1CLC    C1C   32  -0.317  -0.091   0.824
    1CLC    C2C   33  -0.214  -0.193   0.847
    1CLC    C3C   34  -0.112  -0.163   0.760
    1CLC    C4C   35  -0.154  -0.045   0.688
    1CLC    CHD   36  -0.078   0.019   0.591
    1CLC    C1D   37  -0.112   0.131   0.520
    1CLC    C2D   38  -0.033   0.201   0.421
    1CLC    C3D   39  -0.115   0.309   0.380
    1CLC    C4D   40  -0.234   0.301   0.455
    1CLC    CHA   41  -0.325   0.405   0.430
    1CLC    C1A   42  -0.448   0.417   0.491
    1CLC    C2A   43  -0.545   0.533   0.476
    1CLC    C3A   44  -0.657   0.499   0.577
    1CLC    C4A   45  -0.612   0.366   0.634
    1CLC    CHB   46  -0.687   0.294   0.727
    1CLC   HMB1   47  -0.919   0.099   1.010
    1CLC   HMB2   48  -0.868   0.263   0.978
    1CLC   HMB3   49  -0.941   0.167   0.851
    1CLC    HAB   50  -0.629  -0.151   1.086
    1CLC   HBB1   51  -0.831  -0.182   1.180
    1CLC   HBB2   52  -0.905  -0.049   1.074
    1CLC   HMC1   53  -0.317  -0.294   1.000
    1CLC   HMC2   54  -0.143  -0.294   1.018
    1CLC   HMC3   55  -0.219  -0.397   0.899
    1CLC   HAC1   56   0.029  -0.295   0.831
    1CLC   HAC2   57   0.089  -0.162   0.718
    1CLC   HBC1   58   0.108  -0.382   0.619
    1CLC   HBC2   59  -0.063  -0.406   0.643
    1CLC   HBC3   60  -0.006  -0.280   0.536
    1CLC   HMD1   61   0.139   0.078   0.430
    1CLC   HMD2   62   0.172   0.246   0.397
    1CLC   HMD3   63   0.106   0.144   0.272
    1CLC    HBD   64  -0.320   0.500   0.234
    1CLC   HAA1   65  -0.661   0.476   0.307
    1CLC   HAA2   66  -0.512   0.580   0.271
    1CLC   HBA1   67  -0.774   0.656   0.383
    1CLC   HBA2   68  -0.622   0.762   0.367
    1CLC   HMA1   69  -0.751   0.575   0.753
    1CLC   HMA2   70  -0.580   0.612   0.740
    1CLC   HMA3   71  -0.696   0.698   0.642
    1CLC   HED1   72  -0.082   0.795   0.592
    1CLC   HED2   73  -0.245   0.827   0.538
    1CLC   HED3   74  -0.111   0.846   0.427
    1CLC    H11   75  -0.949   0.960   0.123
    1CLC    H12   76  -0.927   0.809   0.037
    1CLC    H13   77  -0.799   0.929   0.037
    1CLC    HHC   78  -0.460  -0.161   0.963
    1CLC    HHD   79   0.018  -0.024   0.570
    1CLC    H2A   80  -0.497   0.626   0.495
    1CLC    H3A   81  -0.754   0.495   0.531
    1CLC    HHB   82  -0.785   0.334   0.746
   0.87600   2.58600   0.73936   0.00000   0.00000   0.00000   0.00000 
-0.41322   0.00000


Could you suggest some possible reasons for the bad result of MD run?

Thank you,
Lu



---------------------------- Original Message ----------------------------
Subject: Re: [gmx-users] how to simulate crystals in Gromacs
From:    "Mark Abraham" <Mark.Abraham at anu.edu.au>
Date:    Thu, April 7, 2011 12:05 pm
To:      "Discussion list for GROMACS users" <gmx-users at gromacs.org>
--------------------------------------------------------------------------

On 7/04/2011 1:55 PM, ZHANG Lu wrote:
> Dear all,
>    I am now trying to simulate crystals in Gromacs.
>    What I did was to convert the original crystal structure in cif format
> to pdb format and then use genconf to replicate the cells and run MD.
>    Is it proper to do it in this way?

It's workable. Whether you need to replicate depends on the size of the
periodic cell. Whether your box had enough space around the "outer"
atoms is also a concern.

>  Because the structure I got after MD
> run was completely a mess ( not like crystals any more).
>    Could anyone tell me the correct way to do MD simulation in crystal
> environment?

There are a large number of possible reasons of the problem. We simply
do not have enough information to suggest anything.

Mark
-- 
gmx-users mailing list    gmx-users at gromacs.org
http://lists.gromacs.org/mailman/listinfo/gmx-users
Please search the archive at
http://www.gromacs.org/Support/Mailing_Lists/Search before posting!
Please don't post (un)subscribe requests to the list. Use the
www interface or send it to gmx-users-request at gromacs.org.
Can't post? Read http://www.gromacs.org/Support/Mailing_Lists





More information about the gromacs.org_gmx-users mailing list