[gmx-users] surface tension vs. system size

Elisabeth katesedate at gmail.com
Fri Mar 25 02:46:24 CET 2011


Dear all,

I performed surface tension calculations vs. different system size (NVT, mdp
file is included at the end). The reported surface tension for hydrocarbon I
am studying is 18 mN/m at 20C. I am getting ~ 175 bar nm from g_energy which
means surface tension of  around 9 mN/m. For box size 3 3 6 nm I get 202 bar
nm which is 10 mN/m and is closer to the reported one.

0-Are my results reasonable? Is it possible to get closer to the actual
surf. ten? or the current difference can not be improved by molecular
dynamics?

1- I am just wondering how I can decide on the system size given runs
performed (shown below). Which system I can stick to?

2- Can I conclude that surface tension I am getting is equilibrated one?
RMSD is much larger than average!!

There are 125 molecules in a 3 3 3 nm box initially. *F*or 6 6 ? runs: 3 3 3
was replicated in X and Y. (that is 4*125 molecules)

*box size 6 6 18 nm (molecules fill up volume of 6 6 3 and Z direction is
increased to 18 so total size is 6 6 18)
*
Statistics over 898601 steps [ *0.0000 through 1797.2001 ps ]*, 1 data sets
All statistics are over 898601 points

Energy                      Average   Err.Est.       RMSD  Tot-Drift
-------------------------------------------------------------------------------
#Surf*SurfTen                175.32        2.9    1813.06     -17.41
(kJ/mol)


Statistics over 818001 steps [ *0.0000 through 1636.0001 ps* ], 1 data sets
All statistics are over 818001 points

Energy                      Average   Err.Est.       RMSD  Tot-Drift
-------------------------------------------------------------------------------
#Surf*SurfTen               175.482        4.9    1814.64   -19.6398
(kJ/mol)

Statistics over 569501 steps [ *500.0000 through 1639.0001 ps* ], 1 data
sets
All statistics are over 569501 points

Energy                      Average   Err.Est.       RMSD  Tot-Drift
-------------------------------------------------------------------------------
#Surf*SurfTen               175.459          5    1815.85   -31.5002
(kJ/mol)

Statistics over 321001 steps [* 1000.0001 through 1642.0001 ps ]*, 1 data
sets
All statistics are over 321001 points

Energy                      Average   Err.Est.       RMSD  Tot-Drift
-------------------------------------------------------------------------------
#Surf*SurfTen               168.128        3.9    1812.23   -12.0096
(kJ/mol)
--------------------------------------------------------------------------------------------------------------------------------------------------------------------
*box size 6 6 8 nm. (molecules fill up volume of 6 6 3 and Z direction is
increased to 8 so total size is 6 6 8)

*Statistics over 1000001 steps [* 0.0000 through 2000.0001 ps *], 1 data
sets
All statistics are over 1000001 points

Energy                      Average   Err.Est.       RMSD  Tot-Drift
-------------------------------------------------------------------------------
#Surf*SurfTen               177.274        3.9    1819.27  -0.465725
(kJ/mol)*
*
Statistics over 750001 steps *[ 500.0000 through 2000.0001 ps ],* 1 data
sets
All statistics are over 750001 points

Energy                      Average   Err.Est.       RMSD  Tot-Drift
-------------------------------------------------------------------------------
#Surf*SurfTen               176.247        3.7    1817.88    12.2119
(kJ/mol)
*
*
-------------------------------------------------------------------------------------------------------------------------------------------------------------------------
*box size 6 6 6 nm. (molecules fill up volume of 6 6 3 and Z direction is
increased to 6 so total size is 6 6 6)

*Statistics over 532601 steps [ 0.0000 through 1065.2001 ps ], 1 data sets
All statistics are over 532601 points

Energy                      Average   Err.Est.       RMSD  Tot-Drift
-------------------------------------------------------------------------------
#Surf*SurfTen               175.137        2.2    1816.63   -2.51592
(kJ/mol)

Statistics over 282601 steps [ *500.0000 through 1065.2001 ps* ], 1 data
sets
All statistics are over 282601 points

Energy                      Average   Err.Est.       RMSD  Tot-Drift
-------------------------------------------------------------------------------
#Surf*SurfTen               178.413        7.6    1815.25   -21.8612
(kJ/mol)

-------------------------------------------------------------------------------------------------
*box size 3 3 9 nm. (molecules fill up volume of 3 3 3 and Z direction is
increased to 9 so total size is 3 3 9)*

Statistics over 1000001 steps [ 0.0000 through 2000.0001 ps ], 1 data sets
All statistics are over 1000001 points

Energy                      Average   Err.Est.       RMSD  Tot-Drift
-------------------------------------------------------------------------------
#Surf*SurfTen               180.985        8.2    3621.55    18.4731
(kJ/mol)

Statistics over 750001 steps [ 500.0000 through 2000.0001 ps ], 1 data sets
All statistics are over 750001 points

Energy                      Average   Err.Est.       RMSD  Tot-Drift
-------------------------------------------------------------------------------
#Surf*SurfTen               186.314        4.6    3613.31   -15.9818
(kJ/mol)\

Statistics over 500001 steps [ 1000.0001 through 2000.0001 ps ], 1 data sets
All statistics are over 500001 points

Energy                      Average   Err.Est.       RMSD  Tot-Drift
-------------------------------------------------------------------------------
#Surf*SurfTen               181.459        5.5    3614.08    10.9469
(kJ/mol)

-------------------------------------------------------------------------------------------------------------------------------------------------------------

*box size 3 3 6 nm. (molecules fill up volume of 3 3 3 and Z direction is
increased to 6 so total size is 3 3 6)*

Statistics over 1000001 steps [ *0.0000 through 2000.0001 ps* ], 1 data sets
All statistics are over 1000001 points

Energy                      Average   Err.Est.       RMSD  Tot-Drift
-------------------------------------------------------------------------------
#Surf*SurfTen                202.46        9.1    3619.78    17.2976
(kJ/mol)

Statistics over 750001 steps [ *500.0000 through 2000.0001 ps* ], 1 data
sets
All statistics are over 750001 points

Energy                      Average   Err.Est.       RMSD  Tot-Drift
-------------------------------------------------------------------------------
#Surf*SurfTen               201.403         12    3610.81    40.9167
(kJ/mol)


Statistics over 500001 steps [ *1000.0001 through 2000.0001 ps* ], 1 data
sets
All statistics are over 500001 points

Energy                      Average   Err.Est.       RMSD  Tot-Drift
----------------------------------------------------------------------------
#Surf*SurfTen               212.306        7.7    3607.07   -30.9386
(kJ/mol)

-------------------------------------------------------------------------------------------------------------------------------------------------------------------------

3- This last trial gives surf ten of 10 mN/m which is closer tp experimental
18 mN/m, although system is 1/4 smaller in number of molecules than 6 6 ?
runs!

4- Also I am attempting to obtain density profile across the box *6 6
8 nm.*( 6 6 3 is filled up and from Z= 3 to 8 is the empty space). Why
am I
getting Segmentation fault?!

g_density -f *.trr -s *.tpr -o density.xvg

Selected 0: 'System'
trn version: GMX_trn_file (single precision)
Last frame      10000 time 2000.000
Segmentation fault


constraints             = all-bonds
constraint-algorithm = lincs
pbc              =  xyz

integrator          =  md
dt                  =  0.002
nsteps              =  1000000


nstenergy           =  100
nstxout             =  100
   nstlist             =  10
ns_type             =  grid

coulombtype         =  PME
vdw-type            =  Shift
rcoulomb-switch     =  0
rvdw-switch         =  0
rlist               =  1.2
rcoulomb            =  1.2
rvdw                =  1.0
fourierspacing      =  0.2
fourier_nx          =  0
fourier_ny          =  0
fourier_nz          =  0
pme_order          =  4
ewald_rtol         =  1e-5
optimize_fft      =  yes

ewald_geometry      =  3dc

Tcoupl              =  v-rescale
tc-grps             =  System
tau_t               =  0.1
ref_t               =  300

gen_vel             =  yes
gen_temp            =  300.0
gen_seed            =  173529


Thank you !
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