[gmx-users] problems with pdb2gmx gromacs 3.3.1 version

Mark Abraham Mark.Abraham at anu.edu.au
Fri Feb 17 11:18:05 CET 2012


On 17/02/2012 9:14 PM, francesca vitalini wrote:
> I tried, but apparently the atom that it is looking for exist already
> in the rtp file!!
>
> this is the error
>
> Program pdb2gmx, VERSION 3.3.1
> Source code file: pdb2gmx.c, line: 383
>
> Fatal error:
> Atom CH3 in residue ACE 1 not found in rtp entry with 3 atoms
>               while sorting atoms

CH3 is the atom type for the terminal C, CA is its name. I think you 
have misnamed your atoms in your coordinate file.

Mark

>
>
> and this is the rtp file for residue ACE
>
> [ ACE ]
>   [ atoms ]
>      CA   CH3   0.000     0
>       C     C   0.450     1
>       O     O  -0.450     1
>   [ bonds ]
>       C    CA   gb_27
>       C     O   gb_5
>       C    +N   gb_19
>   [ angles ]
>     CA     C    +N    ga_19
>      O     C    +N    ga_33
>   [ impropers ]
>      C    CA    +N     O    gi_1
>
> [ NH2 ]
>   [ atoms ]
>       N    NT   -0.83    0
>       H1    H   0.415    0
>       H2    H   0.415    0
> [ bonds ]
>        N    H1  gb_2
>        N    H2  gb_2
>       -C    N   gb_9
>   [ angles ]
>       -O -C N  ga_33
>       -CA -C N ga_19
>       -C N H1  ga_23
>       -C N H2  ga_23
>       H1 N H2  ga_24
>   [ dihedrals ]
>      -CA -C N H1 gd_14
>   [ impropers ]
>      -C -O N -CA gi_1
>       N  H H  -C gi_1
>
>
> Any help?
>
>
>
> 2012/2/16 Justin A. Lemkul<jalemkul at vt.edu>:
>>
>> francesca vitalini wrote:
>>> Do you mean that I can just use the new version of pdb2gmx than change
>>> the included forcefield and in case the name of the atoms and it
>>> should work?
>>>
>> You still have to fix the incorrect atom name(s), regardless of version.
>>   You can use a new version to make use of pdb2gmx -ter, if necessary.
>>   Otherwise, your version should work for what you need.
>>
>> -Justin
>>
>>
>>> 2012/2/16 Justin A. Lemkul<jalemkul at vt.edu>:
>>>>
>>>> francesca vitalini wrote:
>>>>> Hi all!
>>>>> I'm trying to create a topology file from the pdb using the pdb2gmx
>>>>> command of gromacs 3.3.1 but I'm encountering some issues. I should
>>>>> use the flag -tar in order to select interactively the termini, but
>>>>> with the old version of gromacs this is not implemented and I cannot
>>>>> use a new one because I need the reverse transformation tool which is
>>>>> only implemented in that version.
>>>>
>>>> The topology format is largely unaffected by differences in version.  A
>>>> few
>>>> moments with a text editor to fix the #include statements written by a
>>>> version in the 4.5.x series would solve any problems.
>>>>
>>>>
>>>>> Here it is the pdb I'm using
>>>>>
>>>>> REMARK
>>>>> ATOM      1 1HH3 ACE     1      -3.547   1.520   1.054
>>>>> ATOM      2  CH3 ACE     1      -3.081   0.536   0.999
>>>>> ATOM      3 2HH3 ACE     1      -3.437   0.016   0.110
>>>>> ATOM      4 3HH3 ACE     1      -3.348  -0.041   1.883
>>>>> ATOM      5  C   ACE     1      -1.570   0.683   0.929
>>>>> ATOM      6  O   ACE     1      -1.051   1.800   0.938
>>>>> ATOM      7  N   ALA     2      -0.862  -0.446   0.851
>>>>> ATOM      8  H   ALA     2      -1.368  -1.322   0.859
>>>>> ATOM      9  CA  ALA     2       0.607  -0.509   0.828
>>>>> ATOM     10  HA  ALA     2       0.997   0.272   1.484
>>>>> ATOM     11  CB  ALA     2       1.025  -1.867   1.412
>>>>> ATOM     12 1HB  ALA     2       2.113  -1.918   1.485
>>>>> ATOM     13 2HB  ALA     2       0.676  -2.677   0.770
>>>>> ATOM     14 3HB  ALA     2       0.604  -1.990   2.411
>>>>> ATOM     15  C   ALA     2       1.238  -0.262  -0.565
>>>>> ATOM     16  O   ALA     2       2.465  -0.181  -0.678
>>>>> ATOM     17  N   NAC     3       0.423  -0.139  -1.620
>>>>> ATOM     18  H   NAC     3      -0.569  -0.212  -1.447
>>>>> ATOM     19  CH3 NAC     3       0.860   0.098  -2.992
>>>>> ATOM     20 1HH3 NAC     3       1.413   1.037  -3.050
>>>>> ATOM     21 2HH3 NAC     3       1.506  -0.718  -3.323
>>>>> ATOM     22 3HH3 NAC     3      -0.006   0.155  -3.652
>>>>> TER
>>>>> END
>>>>>
>>>>>
>>>>> And this is the pdb2gmx command
>>>>> path/pdb2gmx -ignh -missing -f struct1-1.pdb -p ala.top -o ala.gro
>>>>>
>>>>>
>>>>> I use the gromos9653a6 forcefield and the spc water model
>>>>>
>>>>> And this is the error I get
>>>>>
>>>>> There are 2 donors and 2 acceptors
>>>>> There are 2 hydrogen bonds
>>>>> -------------------------------------------------------
>>>>> Program pdb2gmx, VERSION 3.3.1
>>>>> Source code file: pdb2gmx.c, line: 383
>>>>>
>>>>> Fatal error:
>>>>> Atom CH3 in residue ACE 1 not found in rtp entry with 3 atoms
>>>>>             while sorting atoms
>>>>> -------------------------------------------------------
>>>>>
>>>>> Any suggestions?
>>>>
>>>> Check the .rtp file - your atom is named in a way that is inconsistent
>>>> with
>>>> what the force field expects.
>>>>
>>>> -Justin
>>>>
>>>> --
>>>> ========================================
>>>>
>>>> Justin A. Lemkul
>>>> Ph.D. Candidate
>>>> ICTAS Doctoral Scholar
>>>> MILES-IGERT Trainee
>>>> Department of Biochemistry
>>>> Virginia Tech
>>>> Blacksburg, VA
>>>> jalemkul[at]vt.edu | (540) 231-9080
>>>> http://www.bevanlab.biochem.vt.edu/Pages/Personal/justin
>>>>
>>>> ========================================
>>>> --
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>>>
>>>
>>>
>> --
>> ========================================
>>
>> Justin A. Lemkul
>> Ph.D. Candidate
>> ICTAS Doctoral Scholar
>> MILES-IGERT Trainee
>> Department of Biochemistry
>> Virginia Tech
>> Blacksburg, VA
>> jalemkul[at]vt.edu | (540) 231-9080
>> http://www.bevanlab.biochem.vt.edu/Pages/Personal/justin
>>
>> ========================================
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>
>




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