[gmx-users] Re:Ka/Kd

[lloyd riggs]

Quick question,

I went and calculated the Ka/Kd with the g_hbond --> -g_analyze and just wondered, if all my simulations are pulled, does it in the end make any sense, or is there ways to compensate for this.  I assume the h_bond life would be meaningless, as under a normal situation, 2 proteins h-bond lifes could stretch into the seconds (minus fluctuation around a very small bound area)...

any words, etc are appreciated.

Stephan Watkins