[gmx-users] simulated annealing

tarak karmakar tarak20489 at gmail.com
Tue Nov 6 05:14:30 CET 2012


Dear All,

In my test simulation annealing I'm trying to heat my system from 0 K
to 300 k after 10 ps of run. But at the end I see the temperature
didn't reach to 300 K , it's near around 22 K.
So can anyone please correct me in my .mdp file ?



constraints            = none
integrator             = md-vv
dt                     = 0.0005          ; 1fs
nsteps                 = 20000          ; 30ps
nstcomm                = 1
nstxout                = 1000           ; frequency to write
coordinates to output trajectory
nstvout                = 0              ; frequency to write
velocities to output trajectory; the last velocities are always
written
nstfout                = 0              ; frequency to write forces to
output trajectory
nstlog                 = 1000             ; frequency to write
energies to log file
nstenergy              = 1000 ; frequency to write energies to edr file
nstcalcenergy          = 1000
vdwtype                = cut-off
coulombtype            = PME
pbc                    = xyz
table-extension        = 20.0
nstlist                = 100
ns_type                = grid
rlist                  = 1.2

rcoulomb               = 1.2
rvdw                   = 1.2

comm-grps              = system
optimize_fft           = yes

;heating
annealing              = single
annealing_npoints      = 2
annealing_time         = 0 10
annealing_temp         = 0 300

ld_seed                = 8072012
;nsttcouple = 0.001
;temperature coupling is on
Tcoupl = Nose-Hoover
tau_t = 1.0
tc_grps = system
ref_t = 0

;Pressure coupling is off
Pcoupl = no

; Generate velocites is on
gen_vel = yes
gen_temp = 0
gen_seed = 8042012


THE .log FILE

Constraining the starting coordinates (step 0)
RMS relative constraint deviation after constraining: 0.00e+00
Initial temperature: 0 K

Started mdrun on node 0 Tue Nov  6 21:21:05 2012

           Step           Time         Lambda
              0        0.00000        0.00000

Grid: 14 x 14 x 14 cells
Current ref_t for group System:      0.0
   Energies (kJ/mol)
           Bond          Angle    Proper Dih.  Improper Dih.          LJ-14
    6.98365e+02    2.31495e+03    4.34144e+03    9.32563e+01    3.06280e+03
     Coulomb-14        LJ (SR)   Coulomb (SR)   Coul. recip.      Potential
    4.90527e+04    3.16274e+05   -1.60409e+06   -1.10076e+05   -1.33833e+06
    Kinetic En.   Total Energy  Conserved En.    Temperature Pressure (bar)
    0.00000e+00   -1.33833e+06   -1.33833e+06    0.00000e+00    1.63793e+02

           Step           Time         Lambda
           1000        0.50000        0.00000

Current ref_t for group System:     15.0
   Energies (kJ/mol)
           Bond          Angle    Proper Dih.  Improper Dih.          LJ-14
    5.91509e+02    2.27120e+03    4.37612e+03    1.01524e+02    3.13151e+03
     Coulomb-14        LJ (SR)   Coulomb (SR)   Coul. recip.      Potential
    4.91902e+04    2.58594e+05   -1.55303e+06   -1.10344e+05   -1.34512e+06
    Kinetic En.   Total Energy  Conserved En.    Temperature Pressure (bar)
    6.82988e+03   -1.33829e+06   -1.33829e+06    1.08252e+01   -4.10650e+03

           Step           Time         Lambda
           2000        1.00000        0.00000

Current ref_t for group System:     30.0
   Energies (kJ/mol)
           Bond          Angle    Proper Dih.  Improper Dih.          LJ-14
    5.90602e+02    2.30240e+03    4.39329e+03    1.10298e+02    3.15642e+03
     Coulomb-14        LJ (SR)   Coulomb (SR)   Coul. recip.      Potential
    4.91731e+04    2.60786e+05   -1.55644e+06   -1.10395e+05   -1.34632e+06
    Kinetic En.   Total Energy  Conserved En.    Temperature Pressure (bar)
    8.05310e+03   -1.33827e+06   -1.33827e+06    1.27640e+01   -3.72695e+03

..............
..............

Current ref_t for group System:    255.0
   Energies (kJ/mol)
           Bond          Angle    Proper Dih.  Improper Dih.          LJ-14
    6.07478e+02    2.34899e+03    4.43725e+03    1.08744e+02    3.17997e+03
     Coulomb-14        LJ (SR)   Coulomb (SR)   Coul. recip.      Potential
    4.91213e+04    2.69271e+05   -1.57036e+06   -1.10532e+05   -1.35182e+06
    Kinetic En.   Total Energy  Conserved En.    Temperature Pressure (bar)
    1.39095e+04   -1.33791e+06   -1.33791e+06    2.20464e+01   -3.08283e+03

           Step           Time         Lambda
          18000        9.00000        0.00000

Current ref_t for group System:    270.0
   Energies (kJ/mol)
           Bond          Angle    Proper Dih.  Improper Dih.          LJ-14
    6.22035e+02    2.35774e+03    4.41413e+03    1.07439e+02    3.16535e+03
     Coulomb-14        LJ (SR)   Coulomb (SR)   Coul. recip.      Potential
    4.91418e+04    2.69872e+05   -1.57111e+06   -1.10528e+05   -1.35195e+06
    Kinetic En.   Total Energy  Conserved En.    Temperature Pressure (bar)
    1.40644e+04   -1.33789e+06   -1.33789e+06    2.22919e+01   -3.09464e+03

           Step           Time         Lambda
          19000        9.50000        0.00000

Current ref_t for group System:    285.0
   Energies (kJ/mol)
           Bond          Angle    Proper Dih.  Improper Dih.          LJ-14
    6.31355e+02    2.37456e+03    4.40719e+03    1.06998e+02    3.16961e+03
     Coulomb-14        LJ (SR)   Coulomb (SR)   Coul. recip.      Potential
    4.90783e+04    2.69394e+05   -1.57063e+06   -1.10548e+05   -1.35202e+06
    Kinetic En.   Total Energy  Conserved En.    Temperature Pressure (bar)
    1.41424e+04   -1.33788e+06   -1.33788e+06    2.24154e+01   -3.29328e+03

           Step           Time         Lambda
          20000       10.00000        0.00000

Writing checkpoint, step 20000 at Tue Nov  6 21:39:16 2012


Current ref_t for group System:    300.0
   Energies (kJ/mol)
           Bond          Angle    Proper Dih.  Improper Dih.          LJ-14
    6.25626e+02    2.36220e+03    4.42870e+03    1.05787e+02    3.16930e+03
     Coulomb-14        LJ (SR)   Coulomb (SR)   Coul. recip.      Potential
    4.91428e+04    2.69664e+05   -1.57107e+06   -1.10530e+05   -1.35210e+06
    Kinetic En.   Total Energy  Conserved En.    Temperature Pressure (bar)
    1.42464e+04   -1.33786e+06   -1.33786e+06    2.25803e+01   -3.15481e+03



Thanks for ur help.

-- 
Tarak



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