[gmx-users] NMR restrained MD

Rama Krishna Koppisetti ramkishna72 at gmail.com
Thu Sep 12 15:21:39 CEST 2013


Hi

[ bondedtypes ]
; Col 1: Type of bond
; Col 2: Type of angles
; Col 3: Type of proper dihedrals
; Col 4: Type of improper dihedrals
; Col 5: Generate all dihedrals if 1, only heavy atoms of 0.
; Col 6: Number of excluded neighbors for nonbonded interactions
; Col 7: Generate 1,4 interactions between pairs of hydrogens if 1
; Col 8: Remove propers over the same bond as an improper if it is 1
; bonds  angles  dihedrals  impropers all_dihedrals nrexcl HH14 RemoveDih
     1       1        3        1        1         3      1     0


[ DMPC ]
 [ atoms ]
;    ai   Ber_type charge  chgnr    mass
     CN1    LC3    0.4000    1    15.0350
     CN2    LC3    0.4000    1      15.0350
     CN3    LC3    0.4000    1    15.0350
     NTM    LNL   -0.5000    1    14.0067
      CA    LH2    0.3000    1    14.0270
      CB    LC2    0.4000    2    14.0270
      OA    LOS   -0.8000    2    15.9994
       P     LP    1.7000    2    30.9738
      OB    LOM   -0.8000    2    15.9994
      OC    LOM   -0.8000    2    15.9994
      OD    LOS   -0.7000    2    15.9994
      CC    LC2    0.4000    3    14.0270
      CD    LH1    0.3000    3    13.0190

Now I'm trying to execute command to get ions.tpr file

> grompp -f minim.mdp -c conf_solv.gro -p topol.top -o ions.tpr
>>
>
Error encountered was:

------------------------------
>
> ------------------------
> Program g_grompp, VERSION 4.5.5
> Source code file: /builddir/build/BUILD/gromacs-4.5.5/src/kernel/toppush.c,
> line: 1631
>
> Fatal error:
> Incorrect number of parameters - found 3, expected 2 or 4 for Bond.
> For more information and tips for troubleshooting, please check the GROMACS
> website at http://www.gromacs.org/Documentation/Errors
> -------------------------------------------------------
>


Thanks
--Rama




On Wed, Sep 11, 2013 at 6:47 PM, Justin Lemkul <jalemkul at vt.edu> wrote:

>
>
> On 9/11/13 6:19 PM, Rama Krishna Koppisetti wrote:
>
>> Hi,
>>
>> I wrote an entry in the rtp file  of the force field OPLS-AA + Berger
>> lipid
>> parameters
>>
>> [ DMPC ]
>>   [ atoms ]
>> ;    ai     Ber_type charge  resnr  mass
>>       CN1    LC3    0.4000    1    15.0350
>>       CN2    LC3    0.4000    1      15.0350
>>       CN3    LC3    0.4000    1    15.0350
>>       NTM    LNL   -0.5000    1    14.0067
>>        CA    LH2    0.3000    1    14.0270
>>        CB    LC2    0.4000    1    14.0270
>>        OA    LOS   -0.8000    1    15.9994
>>         P     LP    1.7000    1    30.9738
>>        OB    LOM   -0.8000    1    15.9994
>>        OC    LOM   -0.8000    1    15.9994
>>        OD    LOS   -0.7000    1    15.9994
>>   [ bonds ]
>> ;  ai    aj  funct   c0         c1
>>     CN1  NTM    2   0.1470   8.7100e+06
>>     CN2  NTM    2   0.1470   8.7100e+06
>>     CN3  NTM    2   0.1470   8.7100e+06
>>     NTM   CA    2   0.1470   8.7100e+06
>>      CA   CB    2   0.1530   7.1500e+06
>>      CB   OA    2   0.1430   8.1800e+06
>>      OA    P    2   0.1610   4.8400e+06
>>       P   OB    2   0.1480   8.6000e+06
>>       P   OC    2   0.1480   8.6000e+06
>>       P   OD    2   0.1610   4.8400e+06
>>      OD   CC    2   0.1430   8.1800e+06
>> [ angles ]
>> ;  ai   aj   ak  funct   angle     fc
>>    CN1  NTM   CN2   2    109.50   520.00
>>    CN1  NTM   CN3   2    109.50   520.00
>>    CN1  NTM    CA   2    109.50   520.00
>>    CN2  NTM   CN3   2    109.50   520.00
>>    CN2  NTM    CA   2    109.50   520.00
>>    CN3  NTM    CA   2    109.50   520.00
>>    NTM   CA    CB   2    111.00   530.00
>>     CA   CB    OA   2    111.00   530.00
>>     CB   OA     P   2    120.00   530.00
>>     OA    P    OC   2    109.60   450.00
>>     OA    P    OB   2    109.60   450.00
>>     OA    P    OD   2    103.00   420.00
>>   [ dihedrals ]
>> ;  ai   aj   ak   al   funct    ph0      cp    mult
>>    CN3  NTM   CA   CB    1      0.00     3.77    3
>>    NTM   CA   CB   OA    1      0.00     8.62    3
>>     CA   CB   OA    P    1      0.00     3.77    3
>>     CB   OA    P   OD    1      0.00     3.19    3
>>     OA    P   OD   CC    1      0.00     3.19    3
>>      P   OD   CC   CD    1      0.00     3.77    3
>>     OD   CC   CD   CE    1      0.00     5.92    3
>>     CC   CD   OE  C1A    1      0.00     3.77    3
>>     CC   CD   CE   OG    1      0.00     5.92    3
>>     CD   OE  C1A  C1B    1    180.00    24.00    2
>> [ impropers ]
>> ; GROMOS improper dihedrals
>> ;  ai   aj   ak   al  funct   angle     fc
>> ;  CD   OE   CE   CC    2     35.26   334.72
>>    C1A   OE   OF  C1B    2      0.00   167.36
>>    C2A   OG   OH  C2B    2      0.00   167.36
>>
>> I got a conf.gro file by using merge command
>>
>> pdb2gmx -f system.pdb -merge all
>>
>> Some part of the output file from above command
>>
>> 262TYR      O 2500   2.592   4.761  10.187
>>    263GLY      N 2501   2.782   4.734  10.302
>>    263GLY      H 2502   2.879   4.719  10.299
>>    263GLY     CA 2503   2.716   4.747  10.431
>>    263GLY    HA1 2504   2.787   4.723  10.509
>>    263GLY    HA2 2505   2.635   4.677  10.435
>>    263GLY      C 2506   2.663   4.886  10.455
>>    263GLY     O1 2507   2.645   4.925  10.570
>>    263GLY     O2 2508   2.640   4.967  10.361
>>    264ZN      ZN 2509   4.326   3.894   9.500
>>    265ZN      ZN 2510   4.221   3.718   8.159
>>    266CA      CA 2511   4.917   3.016   8.702
>>    267CA      CA 2512   3.073   4.064   8.337
>>    268CA      CA 2513   4.476   2.192   8.391
>>      1DMPC   CN1 2514   4.712   3.345   3.963
>>      1DMPC   CN2 2515   4.507   3.298   4.076
>>      1DMPC   CN3 2516   4.587   3.524   4.058
>>      1DMPC   NTM 2517   4.576   3.394   3.989
>>      1DMPC    CA 2518   4.511   3.404   3.857
>>      1DMPC    CB 2519   4.465   3.280   3.780
>>      1DMPC    OA 2520   4.576   3.195   3.752
>>      1DMPC     P 2521   4.533   3.055   3.686
>>      1DMPC    OB 2522   4.421   2.996   3.764
>>      1DMPC    OC 2523   4.528   3.081   3.540
>>
>> Now I'm trying to execute command to get ions.tpr file
>>
>>> grompp -f minim.mdp -c conf_solv.gro -p topol.top -o ions.tpr
>>>>
>>>
>> Error encountered was:
>>
>> ------------------------------**------------------------
>> Program g_grompp, VERSION 4.5.5
>> Source code file: /builddir/build/BUILD/gromacs-**
>> 4.5.5/src/kernel/toppush.c,
>> line: 1631
>>
>> Fatal error:
>> Incorrect number of parameters - found 3, expected 2 or 4 for Bond.
>> For more information and tips for troubleshooting, please check the
>> GROMACS
>> website at http://www.gromacs.org/**Documentation/Errors<http://www.gromacs.org/Documentation/Errors>
>> ------------------------------**-------------------------
>>
>> I tried to look all the parameters in the .rtp file and ffbonded.itp and
>> ffnonbonded.itp files I don't find any mistake.
>>
>
> Your .rtp format is wrong.  The directives for bonded interactions do not
> contain function types; these are specified in one line at the top of the
> .rtp file.  Consult manual section 5.6.1.
>
> -Justin
>
>
> --
> ==============================**====================
>
> Justin A. Lemkul, Ph.D.
> Postdoctoral Fellow
>
> Department of Pharmaceutical Sciences
> School of Pharmacy
> Health Sciences Facility II, Room 601
> University of Maryland, Baltimore
> 20 Penn St.
> Baltimore, MD 21201
>
> jalemkul at outerbanks.umaryland.**edu <jalemkul at outerbanks.umaryland.edu> | (410)
> 706-7441
>
> ==============================**====================
> --
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