[gmx-users] NMR restrained MD

Rama Krishna Koppisetti ramkishna72 at gmail.com
Thu Sep 12 17:03:53 CEST 2013


Hi,
These are the parameters I kept in the .rtp file for DMPC molecule. Still
getting same error message should I need to look at somewhere else.

[ bondedtypes ]
; Col 1: Type of bond
; Col 2: Type of angles
; Col 3: Type of proper dihedrals
; Col 4: Type of improper dihedrals
; Col 5: Generate all dihedrals if 1, only heavy atoms of 0.
; Col 6: Number of excluded neighbors for nonbonded interactions
; Col 7: Generate 1,4 interactions between pairs of hydrogens if 1
; Col 8: Remove propers over the same bond as an improper if it is 1
; bonds  angles  dihedrals  impropers all_dihedrals nrexcl HH14 RemoveDih
     1       1        3        1        1         3      1     0


[ DMPC ]
 [ atoms ]
;   name    type    charge  chgnr
     CN1    LC3    0.4000    1
     CN2    LC3    0.4000    1
     CN3    LC3    0.4000    1
     NTM    LNL   -0.5000    1
      CA    LH2    0.3000    1
      CB    LC2    0.4000    2
      OA    LOS   -0.8000    2
       P     LP    1.7000    2
      OB    LOM   -0.8000    2
      OC    LOM   -0.8000    2
      OD    LOS   -0.7000    2
[ bonds ]
;  ai    aj
   CN1  NTM
   CN2  NTM
   CN3  NTM
   NTM   CA
    CA   CB
    CB   OA
    OA    P
     P   OB
     P   OC
     P   OD
    OD   CC
    CC   CD
    CD   OE
    CD   CE
    OE  C1A
 [ angles ]
;  ai   aj   ak  funct   angle     fc
  CN1  NTM   CN2   2    109.50   520.00
  CN1  NTM   CN3   2    109.50   520.00
  CN1  NTM    CA   2    109.50   520.00
  CN2  NTM   CN3   2    109.50   520.00
  CN2  NTM    CA   2    109.50   520.00
  CN3  NTM    CA   2    109.50   520.00
  NTM   CA    CB   2    111.00   530.00
   CA   CB    OA   2    111.00   530.00
   CB   OA     P   2    120.00   530.00
   OA    P    OC   2    109.60   450.00
   OA    P    OB   2    109.60   450.00
   OA    P    OD   2    103.00   420.00
    P   OD    CC   2    120.00   530.00
   OC    P    OB   2    120.00   780.00
   OC    P    OD   2    109.60   450.00
 [ dihedrals ]
;  ai   aj   ak   al   funct    ph0      cp    mult
  CN3  NTM   CA   CB    1      0.00     3.77    3
  NTM   CA   CB   OA    1      0.00     8.62    3
   CA   CB   OA    P    1      0.00     3.77    3
   CB   OA    P   OD    1      0.00     3.19    3
   OA    P   OD   CC    1      0.00     3.19    3
    P   OD   CC   CD    1      0.00     3.77    3
   OD   CC   CD   CE    1      0.00     5.92    3
   CC   CD   OE  C1A    1      0.00     3.77    3
   CC   CD   CE   OG    1      0.00     5.92    3
   CD   OE  C1A  C1B    1    180.00    24.00    2
   CD   CE   OG  C2A    1      0.00     3.77    3
   OE  C1A  C1B  C1C    1      0.00     1.00    6
[ impropers ]
; GROMOS improper dihedrals
;  ai   aj   ak   al  funct   angle     fc
   CD   OE   CE   CC    2     35.26   334.72
  C1A   OE   OF  C1B    2      0.00   167.36
  C2A   OG   OH  C2B    2      0.00   167.36

Thanks
--Rama


On Thu, Sep 12, 2013 at 8:28 AM, Justin Lemkul <jalemkul at vt.edu> wrote:

>
>
> On 9/12/13 9:21 AM, Rama Krishna Koppisetti wrote:
>
>> Hi
>>
>> [ bondedtypes ]
>> ; Col 1: Type of bond
>> ; Col 2: Type of angles
>> ; Col 3: Type of proper dihedrals
>> ; Col 4: Type of improper dihedrals
>> ; Col 5: Generate all dihedrals if 1, only heavy atoms of 0.
>> ; Col 6: Number of excluded neighbors for nonbonded interactions
>> ; Col 7: Generate 1,4 interactions between pairs of hydrogens if 1
>> ; Col 8: Remove propers over the same bond as an improper if it is 1
>> ; bonds  angles  dihedrals  impropers all_dihedrals nrexcl HH14 RemoveDih
>>       1       1        3        1        1         3      1     0
>>
>>
>> [ DMPC ]
>>   [ atoms ]
>> ;    ai   Ber_type charge  chgnr    mass
>>       CN1    LC3    0.4000    1    15.0350
>>       CN2    LC3    0.4000    1      15.0350
>>       CN3    LC3    0.4000    1    15.0350
>>       NTM    LNL   -0.5000    1    14.0067
>>        CA    LH2    0.3000    1    14.0270
>>        CB    LC2    0.4000    2    14.0270
>>        OA    LOS   -0.8000    2    15.9994
>>         P     LP    1.7000    2    30.9738
>>        OB    LOM   -0.8000    2    15.9994
>>        OC    LOM   -0.8000    2    15.9994
>>        OD    LOS   -0.7000    2    15.9994
>>        CC    LC2    0.4000    3    14.0270
>>        CD    LH1    0.3000    3    13.0190
>>
>> Now I'm trying to execute command to get ions.tpr file
>>
>>  grompp -f minim.mdp -c conf_solv.gro -p topol.top -o ions.tpr
>>>
>>>>
>>>>
>>>  Error encountered was:
>>
>> ------------------------------
>>
>>>
>>> ------------------------
>>> Program g_grompp, VERSION 4.5.5
>>> Source code file: /builddir/build/BUILD/gromacs-**
>>> 4.5.5/src/kernel/toppush.c,
>>> line: 1631
>>>
>>> Fatal error:
>>> Incorrect number of parameters - found 3, expected 2 or 4 for Bond.
>>> For more information and tips for troubleshooting, please check the
>>> GROMACS
>>> website at http://www.gromacs.org/**Documentation/Errors<http://www.gromacs.org/Documentation/Errors>
>>> ------------------------------**-------------------------
>>>
>>>
> Given that it's the same error as before, either (1) you didn't fix the
> bonded directives within [DMPC] (not shown above) or (2) you did not
> re-create the topology with the corrected .rtp file.  Remember that the
> contents of an .rtp file are irrelevant once pdb2gmx is done.
>
>
> -Justin
>
> --
> ==============================**====================
>
> Justin A. Lemkul, Ph.D.
> Postdoctoral Fellow
>
> Department of Pharmaceutical Sciences
> School of Pharmacy
> Health Sciences Facility II, Room 601
> University of Maryland, Baltimore
> 20 Penn St.
> Baltimore, MD 21201
>
> jalemkul at outerbanks.umaryland.**edu <jalemkul at outerbanks.umaryland.edu> | (410)
> 706-7441
>
> ==============================**====================
> --
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