[gmx-users] grompp Warning: atom name 20 in p2.top and p2.pdb does not match

Justin Lemkul jalemkul at vt.edu
Mon Sep 23 02:34:54 CEST 2013



On 9/22/13 7:13 PM, Nilesh Dhumal wrote:
> Hello,
>
> I am doing energy minimization for my system.  I am getting following
> warnings
>
> Warning: atom name 20 in p2.top and p2.pdb does not match (C - S20)
> Warning: atom name 21 in p2.top and p2.pdb does not match (C2 - O21)
> Warning: atom name 22 in p2.top and p2.pdb does not match (N3 - O22)
> Warning: atom name 23 in p2.top and p2.pdb does not match (C4 - O23)
> Warning: atom name 24 in p2.top and p2.pdb does not match (N5 - O24)
> Warning: atom name 25 in p2.top and p2.pdb does not match (C6 - C25)
> Warning: atom name 26 in p2.top and p2.pdb does not match (C7 - C26)
> Warning: atom name 27 in p2.top and p2.pdb does not match (C8 - H27)
> Warning: atom name 28 in p2.top and p2.pdb does not match (H9 - H28)
> Warning: atom name 29 in p2.top and p2.pdb does not match (H10 - H29)
> Warning: atom name 30 in p2.top and p2.pdb does not match (H11 - H30)
> Warning: atom name 31 in p2.top and p2.pdb does not match (H12 - H31)
> Warning: atom name 32 in p2.top and p2.pdb does not match (H13 - C)
> Warning: atom name 33 in p2.top and p2.pdb does not match (H14 - C2)
> Warning: atom name 34 in p2.top and p2.pdb does not match (H15 - N3)
> Warning: atom name 35 in p2.top and p2.pdb does not match (H16 - C4)
> Warning: atom name 36 in p2.top and p2.pdb does not match (H17 - N5)
> Warning: atom name 37 in p2.top and p2.pdb does not match (H18 - C6)
> Warning: atom name 38 in p2.top and p2.pdb does not match (H19 - C7)
> Warning: atom name 39 in p2.top and p2.pdb does not match (S20 - C8)
>
>
> Here is .pdb file
>
> TITLE     Protein
> REMARK    THIS IS A SIMULATION BOX
> CRYST1   34.775   34.775   34.775  90.00  90.00  90.00 P 1           1
> MODEL        1
> ATOM      1  C   EMI     1       4.659  30.489  15.747  1.00  0.00
> ATOM      2  C2  EMI     1       5.238  30.284  14.495  1.00  0.00
> ATOM      3  N3  EMI     1       6.415  30.946  14.495  1.00  0.00
> ATOM      4  C4  EMI     1       6.627  31.499  15.682  1.00  0.00
> ATOM      5  N5  EMI     1       5.595  31.153  16.470  1.00  0.00
> ATOM      6  C6  EMI     1       5.462  31.463  17.884  1.00  0.00
> ATOM      7  C7  EMI     1       4.501  30.509  18.615  1.00  0.00
> ATOM      8  C8  EMI     1       7.321  30.993  13.363  1.00  0.00
> ATOM      9  H9  EMI     1       3.672  30.193  16.130  1.00  0.00
> ATOM     10  H10 EMI     1       4.839  29.853  13.640  1.00  0.00
> ATOM     11  H11 EMI     1       7.514  32.004  16.038  1.00  0.00
> ATOM     12  H12 EMI     1       7.951  31.796  13.329  1.00  0.00
> ATOM     13  H13 EMI     1       7.967  30.145  13.270  1.00  0.00
> ATOM     14  H14 EMI     1       6.890  31.170  12.362  1.00  0.00
> ATOM     15  H15 EMI     1       5.214  32.491  18.125  1.00  0.00
> ATOM     16  H16 EMI     1       6.495  31.335  18.302  1.00  0.00
> ATOM     17  H17 EMI     1       4.834  29.492  18.590  1.00  0.00
> ATOM     18  H18 EMI     1       4.337  30.767  19.685  1.00  0.00
> ATOM     19  H19 EMI     1       3.486  30.669  18.338  1.00  0.00
> ATOM     20  S20 ETS     2      13.817   2.976  33.669  1.00  0.00
> ATOM     21  O21 ETS     2      15.031   2.685  34.347  1.00  0.00
> ATOM     22  O22 ETS     2      14.005   3.313  32.237  1.00  0.00
> ATOM     23  O23 ETS     2      12.775   1.970  33.860  1.00  0.00
> ATOM     24  O24 ETS     2      13.303   4.314  34.278  1.00  0.00
> ATOM     25  C25 ETS     2      12.361   5.280  33.781  1.00  0.00
> ATOM     26  C26 ETS     2      12.277   6.501  34.666  1.00  0.00
> ATOM     27  H27 ETS     2      12.582   5.675  32.806  1.00  0.00
> ATOM     28  H28 ETS     2      11.377   4.787  33.550  1.00  0.00
> ATOM     29  H29 ETS     2      11.686   6.245  35.492  1.00  0.00
> ATOM     30  H30 ETS     2      13.256   6.810  34.975  1.00  0.00
> ATOM     31  H31 ETS     2      11.856   7.349  34.171  1.00  0.00
> ATOM     32  C   EMI     3      25.075  29.706   5.816  1.00  0.00
> ATOM     33  C2  EMI     3      24.256  29.876   6.894  1.00  0.00
>
> and .top file is
> [ atoms ]
> ;   nr       type  resnr residue  atom   cgnr     charge       mass  typeB
>     chargeB      massB
>       1   opls_561      1    EMI      C      1      -0.13     12.011   ;
> qtot -0.13
>       2   opls_561      1    EMI     C2      2      -0.13     12.011   ;
> qtot -0.26
>       3   opls_557      1    EMI     N3      3       0.15    14.0067   ;
> qtot -0.11
>       4   opls_558      1    EMI     C4      4      -0.11     12.011   ;
> qtot -0.22
>       5   opls_557      1    EMI     N5      5       0.15    14.0067   ;
> qtot -0.07
>       6   opls_136      1    EMI     C6      6      -0.05     12.011   ;
> qtot -0.12
>       7   opls_135      1    EMI     C7      7      -0.17     12.011   ;
> qtot -0.29
>       8   opls_135      1    EMI     C8      8      -0.17     12.011   ;
> qtot -0.46
>       9   opls_564      1    EMI     H9      9       0.21      1.008   ;
> qtot -0.25
>      10   opls_564      1    EMI    H10      9       0.21      1.008   ;
> qtot -0.04
>      11   opls_563      1    EMI    H11      9       0.21      1.008   ;
> qtot 0.17
>      12   opls_140      1    EMI    H12     10       0.13      1.008   ;
> qtot 0.3
>      13   opls_140      1    EMI    H13     10       0.13      1.008   ;
> qtot 0.43
>      14   opls_140      1    EMI    H14     10       0.13      1.008   ;
> qtot 0.56
>      15   opls_140      1    EMI    H15     11       0.13      1.008   ;
> qtot 0.69
>      16   opls_140      1    EMI    H16     11       0.13      1.008   ;
> qtot 0.82
>      17   opls_140      1    EMI    H17     12       0.06      1.008   ;
> qtot 0.88
>      18   opls_140      1    EMI    H18     12       0.06      1.008   ;
> qtot 0.94
>      19   opls_140      1    EMI    H19     12       0.06      1.008   ;
> qtot 1
>      20   opls_969      2    ETS    S20     13       1.18      32.03   ;
> qtot 2.18
>      21   opls_970      2    ETS    O21     14      -0.65    15.9994   ;
> qtot 1.53
>      22   opls_970      2    ETS    O22     14      -0.65    15.9994   ;
> qtot 0.88
>      23   opls_970      2    ETS    O23     14      -0.65    15.9994   ;
> qtot 0.23
>      24   opls_971      2    ETS    O24     15      -0.45    15.9994   ;
> qtot -0.22
>      25   opls_972      2    ETS    C25     16       0.22     12.011   ;
> qtot 0
>      26   opls_973      2    ETS    C26     17      -0.18     12.011   ;
> qtot -0.18
>      27   opls_974      2    ETS    H27     18          0      1.008   ;
> qtot -0.18
>      28   opls_974      2    ETS    H28     18          0      1.008   ;
> qtot -0.18
>      29   opls_975      2    ETS    H29     19       0.06      1.008   ;
> qtot -0.12
>      30   opls_975      2    ETS    H30     19       0.06      1.008   ;
> qtot -0.06
>      31   opls_975      2    ETS    H31     19       0.06      1.008   ;
> qtot 0
>
>
> Could you tell why am I getting this warnings? I am using VERSION 4.0.7 .
>

The [molecules] section of the topology is out of order with respect to the 
atoms in the coordinate file.  In the absence of the full .top (and any relevant 
.itp files) and coordinate file, there's not much more to guess at.  The error 
shows you that grompp expects an "ETS" residue to have started, but it's finding 
atoms belonging to an "EMI" residue.

-Justin

-- 
==================================================

Justin A. Lemkul, Ph.D.
Postdoctoral Fellow

Department of Pharmaceutical Sciences
School of Pharmacy
Health Sciences Facility II, Room 601
University of Maryland, Baltimore
20 Penn St.
Baltimore, MD 21201

jalemkul at outerbanks.umaryland.edu | (410) 706-7441

==================================================



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