[gmx-users] Too many LINCS warnings

[Jennifer Vo]

Dear Experts,
I am running an nvt equilibration for a System including 2 Proteins and 2
ligands.
I have got this error:




*"Fatal error:Too many LINCS warnings (1000)If you know what you are doing
you can adjust the lincs warning threshold in your mdp fileor set the
environment variable GMX_MAXCONSTRWARN to -1,but normally it is better to
fix the problem"*
Reading from some forums I thought it could be (1) the system was
insufficiently minimized, (2) the .mdp settings are incorrect, and/or (3)
the ligand topology is flawed.
I checked the potential energy after EM and the pdb file, it looks stable
and fine to me. I guess my nvt.mdp file is incorrect (please find them in
attachments).
Could you please guide me where is the incorrect point?
Many thanks for any help.
Regards,
Jennifer