[gmx-users] how to adjust the box size to correct density?

Chang Woon Jang changwoonjang at gmail.com
Tue Jan 5 21:48:53 CET 2016


Dear Mark,

   I see. pcoupl = No is obvious. That means when I create tpr file from
grompp.mdp, the pcoupl setting was No instead of berendsen.

Thank you very much.

Best regards,
Changwoon Jang

On Tue, Jan 5, 2016 at 3:41 PM, Mark Abraham <mark.j.abraham at gmail.com>
wrote:

> Hi,
>
> Look at what md.log says about the value for pcoupl it read from your .tpr.
> :-)
>
> Mark
>
> On Tue, Jan 5, 2016 at 9:39 PM Chang Woon Jang <changwoonjang at gmail.com>
> wrote:
>
> > Dear Mark,
> >
> > I obtained the tpr file with gro and topology file using grompp -v.
> >
> > The following is from md.log file.
> >
> > Best regards,
> > Changwoon Jang
> >
> >
> > Log file opened on Fri Nov 13 13:52:29 2015
> > Host: c438-702.stampede.tacc.utexas.edu  pid: 8923  rank ID: 0  number
> of
> > ranks:  64
> > GROMACS:    mdrun_mpi, VERSION 5.0.6
> >
> > GROMACS is written by:
> > Emile Apol         Rossen Apostolov   Herman J.C. Berendsen Par Bjelkmar
> > Aldert van Buuren  Rudi van Drunen    Anton Feenstra     Sebastian
> Fritsch
> > Gerrit Groenhof    Christoph Junghans Peter Kasson       Carsten Kutzner
> > Per Larsson        Justin A. Lemkul   Magnus Lundborg    Pieter
> Meulenhoff
> > Erik Marklund      Teemu Murtola      Szilard Pall       Sander Pronk
> > Roland Schulz      Alexey Shvetsov    Michael Shirts     Alfons Sijbers
> > Peter Tieleman     Christian Wennberg Maarten Wolf
> > and the project leaders:
> > Mark Abraham, Berk Hess, Erik Lindahl, and David van der Spoel
> >
> > Copyright (c) 1991-2000, University of Groningen, The Netherlands.
> > Copyright (c) 2001-2014, The GROMACS development team at
> > Uppsala University, Stockholm University and
> > the Royal Institute of Technology, Sweden.
> > check out http://www.gromacs.org for more information.
> >
> > GROMACS is free software; you can redistribute it and/or modify it
> > under the terms of the GNU Lesser General Public License
> > as published by the Free Software Foundation; either version 2.1
> > of the License, or (at your option) any later version.
> >
> > GROMACS:      mdrun_mpi, VERSION 5.0.6
> > Executable:
> > /opt/apps/intel15/mvapich2_2_1/gromacs/5.0.6/x86_64/bin/mdrun_mpi
> > Library dir:
> > /opt/apps/intel15/mvapich2_2_1/gromacs/5.0.6/x86_64/share/gromacs/top
> > Command line:
> >   mdrun_mpi -v
> >
> > Gromacs version:    VERSION 5.0.6
> > Precision:          single
> > Memory model:       64 bit
> > MPI library:        MPI
> > OpenMP support:     enabled
> > GPU support:        disabled
> > invsqrt routine:    gmx_software_invsqrt(x)
> > SIMD instructions:  AVX_256
> > FFT library:        Intel MKL
> > RDTSCP usage:       enabled
> > C++11 compilation:  enabled
> > TNG support:        enabled
> > Tracing support:    disabled
> > Built on:           Wed Sep  9 15:35:09 CDT 2015
> > Built by:           micbuild at c560-901.stampede.tacc.utexas.edu [CMAKE]
> > Build OS/arch:      Linux 2.6.32-431.17.1.el6.x86_64 x86_64
> > Build CPU vendor:   GenuineIntel
> > Build CPU brand:    Intel(R) Xeon(R) CPU E5-2680 0 @ 2.70GHz
> > Build CPU family:   6   Model: 45   Stepping: 7
> > Build CPU features: aes apic avx clfsh cmov cx8 cx16 htt lahf_lm mmx msr
> > nonstop_tsc pcid pclmuldq pdcm pdpe1gb popcnt pse rdtscp sse2 sse3 sse4.1
> > sse4.2 ssse3 tdt x2apic
> > C compiler:
> > /opt/apps/intel/15/composer_xe_2015.2.164/bin/intel64/icc Intel
> > 15.0.2.20150121
> > C compiler flags:    -mavx   -mkl=sequential -O3 -funroll-all-loops
> > -std=gnu99 -w3 -wd111 -wd177 -wd181 -wd193 -wd271 -wd304 -wd383 -wd424
> > -wd444 -wd522 -wd593 -wd869 -wd981 -wd1418 -wd1419 -wd1572 -wd1599
> -wd2259
> > -wd2415 -wd2547 -wd2557 -wd3280 -wd3346 -wd11074 -wd11076  -O3 -DNDEBUG
> -ip
> > -funroll-all-loops -alias-const -ansi-alias
> > C++ compiler:
> > /opt/apps/intel/15/composer_xe_2015.2.164/bin/intel64/icpc Intel
> > 15.0.2.20150121
> > C++ compiler flags:  -mavx   -std=c++0x -O3 -funroll-all-loops -w3 -wd111
> > -wd177 -wd181 -wd193 -wd271 -wd304 -wd383 -wd424 -wd444 -wd522 -wd593
> > -wd869 -wd981 -wd1418 -wd1419 -wd1572 -wd1599 -wd2259 -wd2415 -wd2547
> > -wd2557 -wd3280 -wd3346 -wd11074 -wd11076 -wd1782 -wd2282  -O3 -DNDEBUG
> -ip
> > -funroll-all-loops -alias-const -ansi-alias
> > Boost version:      1.55.0 (external)
> >
> > Number of hardware threads detected (16) does not match the number
> reported
> > by OpenMP (1).
> > Consider setting the launch configuration manually!
> > Changing nstlist from 5 to 40, rlist from 1.22 to 1.22
> >
> > Input Parameters:
> >    integrator                     = md
> >    tinit                          = 0
> >    dt                             = 0.001
> >    nsteps                         = 10000000
> >    init-step                      = 0
> >    simulation-part                = 1
> >    comm-mode                      = Linear
> >    nstcomm                        = 50
> >    bd-fric                        = 0
> >    ld-seed                        = 1993
> >    emtol                          = 100
> >    emstep                         = 0.01
> >    niter                          = 20
> >    fcstep                         = 0
> >    nstcgsteep                     = 1000
> >    nbfgscorr                      = 10
> >    rtpi                           = 0.05
> >    nstxout                        = 1000
> >    nstvout                        = 0
> >    nstfout                        = 1000
> >    nstlog                         = 50
> >    nstcalcenergy                  = 50
> >    nstenergy                      = 50
> >    nstxout-compressed             = 0
> >    compressed-x-precision         = 1000
> >    cutoff-scheme                  = Verlet
> >    nstlist                        = 40
> >    ns-type                        = Grid
> >    pbc                            = xyz
> >    periodic-molecules             = FALSE
> >    verlet-buffer-tolerance        = 0.005
> >    rlist                          = 1.22
> >    rlistlong                      = 1.22
> >    nstcalclr                      = 5
> >    coulombtype                    = PME
> >    coulomb-modifier               = Potential-shift
> >    rcoulomb-switch                = 0
> >    rcoulomb                       = 1.22
> >    epsilon-r                      = 1
> >    epsilon-rf                     = inf
> >    vdw-type                       = Cut-off
> >    vdw-modifier                   = Potential-shift
> >    rvdw-switch                    = 0
> >    rvdw                           = 1.22
> >    DispCorr                       = EnerPres
> >    table-extension                = 1
> >    fourierspacing                 = 0.12
> >    fourier-nx                     = 84
> >    fourier-ny                     = 84
> >    fourier-nz                     = 84
> >    pme-order                      = 4
> >    ewald-rtol                     = 1e-05
> >    ewald-rtol-lj                  = 0.001
> >    lj-pme-comb-rule               = Geometric
> >    ewald-geometry                 = 0
> >    epsilon-surface                = 0
> >    implicit-solvent               = No
> >    gb-algorithm                   = Still
> >    nstgbradii                     = 1
> >    rgbradii                       = 2
> >    gb-epsilon-solvent             = 80
> >    gb-saltconc                    = 0
> >    gb-obc-alpha                   = 1
> >    gb-obc-beta                    = 0.8
> >    gb-obc-gamma                   = 4.85
> >    gb-dielectric-offset           = 0.009
> >    sa-algorithm                   = Ace-approximation
> >    sa-surface-tension             = 2.05016
> >    tcoupl                         = Nose-Hoover
> >    nsttcouple                     = 5
> >    nh-chain-length                = 1
> >    print-nose-hoover-chain-variables = FALSE
> >    pcoupl                         = No
> >    pcoupltype                     = Isotropic
> >    nstpcouple                     = -1
> >    tau-p                          = 0.5
> >    compressibility (3x3):
> >       compressibility[    0]={ 0.00000e+00,  0.00000e+00,  0.00000e+00}
> >       compressibility[    1]={ 0.00000e+00,  0.00000e+00,  0.00000e+00}
> >       compressibility[    2]={ 0.00000e+00,  0.00000e+00,  0.00000e+00}
> >    ref-p (3x3):
> >       ref-p[    0]={ 0.00000e+00,  0.00000e+00,  0.00000e+00}
> >       ref-p[    1]={ 0.00000e+00,  0.00000e+00,  0.00000e+00}
> >       ref-p[    2]={ 0.00000e+00,  0.00000e+00,  0.00000e+00}
> >    refcoord-scaling               = No
> >    posres-com (3):
> >       posres-com[0]= 0.00000e+00
> >       posres-com[1]= 0.00000e+00
> >       posres-com[2]= 0.00000e+00
> >    posres-comB (3):
> >       posres-comB[0]= 0.00000e+00
> >       posres-comB[1]= 0.00000e+00
> >       posres-comB[2]= 0.00000e+00
> >
> > ....
> >
> > On Tue, Jan 5, 2016 at 3:07 PM, Mark Abraham <mark.j.abraham at gmail.com>
> > wrote:
> >
> > > Hi,
> > >
> > > On Tue, Jan 5, 2016 at 7:15 PM Chang Woon Jang <
> changwoonjang at gmail.com>
> > > wrote:
> > >
> > > > Dear Gromacs Users,
> > > >
> > > >
> > > > I have a low density polymer system initially. I would like to fit
> the
> > > > correct liquid density using NPT simulation.
> > > >
> > > > I used Pcoupl=berendsen for 22 ns but the box size in confout.gro is
> > > still
> > > > the same as the input size of conf.gro.
> > > >
> > > > Initial in conf.gro (10.0 10.0 9.8)
> > > > output in confout.gro (10.0 10.0 9.8)
> > > >
> > >
> > > That's wildly unlikely if you've used the .tpr with the contents that
> you
> > > think you have. Inspect the top of your .log file to see.
> > >
> > > Mark
> > >
> > >
> > > > My initial conditions are
> > > >
> > > > tau_p=5.0
> > > > compressibility=4.5e-5
> > > > ref_p=1.0
> > > >
> > > > Do I need to increase compressibility?
> > > >
> > > > Thank you.
> > > >
> > > > Best regards,
> > > > Changwoon Jang,
> > > > --
> > > > Gromacs Users mailing list
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> > > >
> > > --
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> >
> >
> >
> > --
> > Best regards,
> > Changwoon Jang,
> >
> > Postdoctoral Research Fellow
> > Department of Chemical & Biological Engineering, Drexel University
> > 3141 Chestnut Street, Philadelphia, PA 19104
> >
> > Voice: (662) 617-2267
> > E-mail: cj395 at drexel.edu
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