[gmx-users] ITD-Modelling

[Mark Abraham]

Torsten Stauder wrote:
>>So the native and the insert structures are known....
>>
>>
>>>Any suggestions how to model such a ITD-sequence into a wild type
>>>receptor?
>>
>>... so what's the problem?
> 
> I wouldn't ask if I'd know how to do that....

Well if you have structures, you can cut and paste them together in any 
number of molecule-building programs. If you don't have structures then 
you have an awkward problem - you now either want to do an homology 
model using some other software, and/or want to guess something vaguely 
reasonable and do an MD simulation and see what you find out.

Mark