[gmx-users] error after mdrun

David van der Spoel spoel at xray.bmc.uu.se
Tue Nov 14 08:08:12 CET 2006


nur avneet wrote:
> Dear All
> I am new to gromacs...please help me and let me know how to 
> proceed..when i give the mdrun command he terminal displays the following:
> 
> /usr/local/gromacs/bin/mdrun -nice 0 -v -s hyb2b_vac_md.tpr -o 
> hyb2b_vac_md_1ns_traj.trr -c hyb2b_vac_md_1ns.gro -e 
> hyb2b_vac_md_1ns_ener.edr -g hyb2b_vac_md_1ns.log
>                          :-)  G  R  O  M  A  C  S  (-:
> 

your starting structure is not minimized enough.


>                                Grunge ROck MAChoS
> 
>                             :-)  VERSION 3.3.1  (-:
> 
> 
>       Written by David van der Spoel, Erik Lindahl, Berk Hess, and others.
>        Copyright (c) 1991-2000, University of Groningen, The Netherlands.
>              Copyright (c) 2001-2006, The GROMACS development team,
>             check out http://www.gromacs.org for more information.
> 
>          This program is free software; you can redistribute it and/or
>           modify it under the terms of the GNU General Public License
>          as published by the Free Software Foundation; either version 2
>              of the License, or (at your option) any later version.
> 
>                      :-)  /usr/local/gromacs/bin/mdrun  (-:
> 
> Option     Filename  Type         Description
> ------------------------------------------------------------
>   -s hyb2b_vac_md.tpr  Input        Generic run input: tpr tpb tpa xml
>   -o hyb2b_vac_md_1ns_traj.trr  Output       Full precision trajectory: trr
>                                    trj
>   -x       traj.xtc  Output, Opt. Compressed trajectory (portable xdr 
> format)
>   -c hyb2b_vac_md_1ns.gro  Output       Generic structure: gro g96 pdb xml
>   -e hyb2b_vac_md_1ns_ener.edr  Output       Generic energy: edr ene
>   -g hyb2b_vac_md_1ns.log  Output       Log file
> -dgdl      dgdl.xvg  Output, Opt. xvgr/xmgr file
> -field    field.xvg  Output, Opt. xvgr/xmgr file
> -table    table.xvg  Input, Opt.  xvgr/xmgr file
> -tablep  tablep.xvg  Input, Opt.  xvgr/xmgr file
> -rerun    rerun.xtc  Input, Opt.  Generic trajectory: xtc trr trj gro 
> g96 pdb
> -tpi        tpi.xvg  Output, Opt. xvgr/xmgr file
>  -ei        sam.edi  Input, Opt.  ED sampling input
>  -eo        sam.edo  Output, Opt. ED sampling output
>   -j       wham.gct  Input, Opt.  General coupling stuff
>  -jo        bam.gct  Output, Opt. General coupling stuff
> -ffout      gct.xvg  Output, Opt. xvgr/xmgr file
> -devout   deviatie.xvg  Output, Opt. xvgr/xmgr file
> -runav  runaver.xvg  Output, Opt. xvgr/xmgr file
>  -pi       pull.ppa  Input, Opt.  Pull parameters
>  -po    pullout.ppa  Output, Opt. Pull parameters
>  -pd       pull.pdo  Output, Opt. Pull data output
>  -pn       pull.ndx  Input, Opt.  Index file
> -mtx         nm.mtx  Output, Opt. Hessian matrix
>  -dn     dipole.ndx  Output, Opt. Index file
> 
>       Option   Type  Value  Description
> ------------------------------------------------------
>       -[no]h   bool     no  Print help info and quit
>       -[no]X   bool     no  Use dialog box GUI to edit command line options
>        -nice    int      0  Set the nicelevel
>      -deffnm string         Set the default filename for all file options
>    -[no]xvgr   bool    yes  Add specific codes (legends etc.) in the output
>                             xvg files for the xmgrace program
>          -np    int      1  Number of nodes, must be the same as used for
>                             grompp
>          -nt    int      1  Number of threads to start on each node
>       -[no]v   bool    yes  Be loud and noisy
> -[no]compact   bool    yes  Write a compact log file
> -[no]sepdvdl   bool     no  Write separate V and dVdl terms for each
>                             interaction type and node to the log file(s)
>   -[no]multi   bool     no  Do multiple simulations in parallel (only with
>                             -np > 1)
>      -replex    int      0  Attempt replica exchange every # steps
>      -reseed    int     -1  Seed for replica exchange, -1 is generate a seed
>    -[no]glas   bool     no  Do glass simulation with special long range
>                             corrections
>  -[no]ionize   bool     no  Do a simulation including the effect of an X-Ray
>                             bombardment on your system
> 
> 
> Back Off! I just backed up hyb2b_vac_md_1ns.log to 
> ./#hyb2b_vac_md_1ns.log.1#
> Getting Loaded...
> Reading file hyb2b_vac_md.tpr, VERSION 3.3.1 (single precision)
> Loaded with Money
> 
> starting mdrun 'DRG'
> 400000 steps,   1000.0 ps.
> 
> step 156610, will finish at Tue Nov 14 11:36:08 2006
> Step 156619, time 391.547 (ps)  LINCS WARNING
> relative constraint deviation after LINCS:
> max 1.235368 (between atoms 9 and 16) rms 0.131218
> bonds that rotated more than 30 degrees:
>  atom 1 atom 2  angle  previous, current, constraint length
>       7      9   45.3    0.1470   0.1738      0.1470
>       9     16   82.0    0.1326   0.2973      0.1330
>      10     11   32.8    0.1530   0.1828      0.1530
>      16     17   89.9    0.1226   0.1771      0.1230
>      16     18   84.2    0.1541   0.2315      0.1530
>      18     19   33.7    0.1470   0.1792      0.1470
> Wrote pdb files with previous and current coordinates
> 
> Step 156620, time 391.55 (ps)  LINCS WARNING
> relative constraint deviation after LINCS:
> max 7.148781 (between atoms 9 and 10) rms 0.983396
> bonds that rotated more than 30 degrees:
>  atom 1 atom 2  angle  previous, current, constraint length
>       7      9   88.7    0.1738   0.4815      0.1470
>       9     10   92.9    0.1596   1.1979      0.1470
>       9     16  128.5    0.2973   0.4633      0.1330
>      10     11   87.8    0.1828   0.9363      0.1530
>      11     12   35.9    0.1280   0.1537      0.1230
>      13     15   32.1    0.1008   0.1164      0.1000
>      16     17  109.7    0.1771   0.8290      0.1230
>      16     18  156.9    0.2315   0.1646      0.1530
>      18     19  102.6    0.1792   0.1550      0.1470
>      24     25   31.7    0.1301   0.1346      0.1230
> 
> Back Off! I just backed up step156619.pdb to ./#step156619.pdb.1#
> Wrote pdb files with previous and current coordinates
> step 156620, will finish at Tue Nov 14 11:36:11 2006Warning: 1-4 
> interaction between 7 and 17 at distance 1.011 which is larger than the 
> 1-4 table size 1.000 nmThese are ignored for the rest of the simulation
> This usually means your system is exploding,
> if not, you should increase table-extension in your mdp file
> 
> Step 156621, time 391.552 (ps)  LINCS WARNING
> relative constraint deviation after LINCS:
> max 12.247591 (between atoms 9 and 16) rms 1.513366
> bonds that rotated more than 30 degrees:
>  atom 1 atom 2  angle  previous, current, constraint length
>       1      2   39.2    0.1386   0.1675      0.1390
>       1      6  113.5    0.1403   0.0654      0.1390
>       4      5   33.6    0.1382   0.1725      0.1390
>       5      6   96.3    0.1412   0.0713      0.1390
>       7      8  114.2    0.1624   0.2766      0.1530
>       7      9  153.7    0.4814   0.9763      0.1470
>       9     10  138.1    1.1977   0.8364      0.1470
>       9     16  109.0    0.4632   1.7619      0.1330
>      10     11  131.9    0.9361   0.5693      0.1530
>      11     12   80.0    0.1536   0.6929      0.1230
>      11     13   86.6    0.1523   0.6955      0.1330
>      13     14   94.6    0.1088   0.3135      0.1000
>      13     15   63.0    0.1164   0.1204      0.1000
>      16     17   89.0    0.8288   0.5757      0.1230
>      16     18  151.6    0.1646   0.5035      0.1530
>      18     19  134.6    0.1550   0.2206      0.1470
>      19     20  106.4    0.1745   0.4050      0.1470
>      19     24  108.6    0.1639   0.4129      0.1330
>      20     21   33.2    0.1613   0.1457      0.1530
>      20     22   55.4    0.1634   0.1288      0.1530
>      22     23   30.6    0.1552   0.1755      0.1530
>      24     25   65.8    0.1345   0.1296      0.1230
> 
> Back Off! I just backed up step156620.pdb to ./#step156620.pdb.1#
> Wrote pdb files with previous and current coordinates
> 
> Step 156622, time 391.555 (ps)  LINCS WARNING
> relative constraint deviation after LINCS:
> max 156.416000 (between atoms 27 and 28) rms 43.887146
> bonds that rotated more than 30 degrees:
>  atom 1 atom 2  angle  previous, current, constraint length
>       1      2  155.9    0.1679   1.3713      0.1390
>       1      6  165.9    0.0656   5.7379      0.1390
>       2      3   89.1    0.1437   0.4223      0.1390
>       3      4   89.4    0.1416   0.3068      0.1390
>       4      5  139.8    0.1730   1.2976      0.1390
>       5      6  169.0    0.0715   5.8196      0.1390
>       6      7  163.1    0.5102  13.7829      0.1530
>       7      8  147.6    0.2774  10.9817      0.1530
>       7      9  160.5    0.9791  16.5650      0.1470
>       9     10  170.4    0.8388  12.9173      0.1470
>       9     16  157.1    1.7670  18.6046      0.1330
>      10     11  160.5    0.5710   9.0364      0.1530
>      11     12  170.7    0.6950   4.6000      0.1230
>      11     13  170.8    0.6975   4.7046      0.1330
>      13     14   77.3    0.3144   1.5544      0.1000
>      13     15   51.3    0.1208   1.6563      0.1000
>      16     17  110.0    0.5774  15.5720      0.1230
>      16     18  118.9    0.5049  15.9163      0.1530
>      18     19   55.9    0.2213  17.6087      0.1470
>      19     20   56.9    0.4062  22.6568      0.1470
>      22     23  132.0    0.1760   1.8040      0.1530
>      24     26   44.3    0.1084  18.9838      0.1530
>      26     27  115.3    0.1651  16.6028      0.1470
>      27     28   78.8    0.1540  23.1402      0.1470
>      27     36   81.3    0.1423  20.7586      0.1330
>      28     29  109.2    0.1587   7.2465      0.1530
>      29     30  103.3    0.1536   3.7558      0.1530
>      30     31   50.5    0.1524   1.3613      0.1530
>      31     32  110.6    0.1476   0.1332      0.1470
>      32     33   65.6    0.1002   0.3047      0.1000
>      32     34   72.2    0.1003   0.3269      0.1000
>      32     35   66.0    0.1002   0.3122      0.1000
>      36     37   91.3    0.1264   8.1830      0.1230
>      36     38   90.4    0.1562   7.6206      0.1530
>      38     39   85.9    0.1482   6.8321      0.1470
>      39     40   72.5    0.1476   0.8344      0.1470
>      39     48   69.1    0.1337   0.9899      0.1330
>      40     41   79.8    0.1535   0.4217      0.1530
>      40     42   79.3    0.1535   0.4262      0.1530
>      42     43   42.2    0.1394   0.1974      0.1390
>      42     47   42.6    0.1394   0.1979      0.1390
>      48     49   68.0    0.1234   0.3369      0.1230
>      48     50   71.2    0.1535   0.4167      0.1530
>      50     51   58.0    0.1475   0.2531      0.1470
> 
> Back Off! I just backed up step156621.pdb to ./#step156621.pdb.1#
> Wrote pdb files with previous and current coordinates
> 
> Step 156623  Warning: pressure scaling more than 1%, mu: 3.98712 3.98712 
> 3.98712
> Step 156623, time 391.557 (ps)  LINCS WARNING
> relative constraint deviation after LINCS:
> max 3.089954 (between atoms 98 and 100) rms nan
> bonds that rotated more than 30 degrees:
>  atom 1 atom 2  angle  previous, current, constraint length
>      61     62   34.3    0.1539   0.1918      0.1530
>      70     71   58.7    0.1479   0.2698      0.1470
>      96     97   36.3    0.1006   0.0909      0.1000
>      96     98   88.0    0.1338   0.3737      0.1330
>      98     99   88.8    0.1539   0.3097      0.1530
>      98    100   89.2    0.1237   0.5031      0.1230
> 
> Back Off! I just backed up step156622.pdb to ./#step156622.pdb.1#
> Wrote pdb files with previous and current coordinates
> -------------------------------------------------------
> Program mdrun, VERSION 3.3.1
> Source code file: nsgrid.c, line: 220
> 
> Fatal error:
> Number of grid cells is zero. Probably the system and box collapsed.
> 
> -------------------------------------------------------
> 
> "I'm Gonna Get Medieval On Your Ass" (Pulp Fiction)
> 
> 
> What is wrong and what should be done.
> 
> redgards
> nur
> 
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-- 
David.
________________________________________________________________________
David van der Spoel, PhD, Assoc. Prof., Molecular Biophysics group,
Dept. of Cell and Molecular Biology, Uppsala University.
Husargatan 3, Box 596,  	75124 Uppsala, Sweden
phone:	46 18 471 4205		fax: 46 18 511 755
spoel at xray.bmc.uu.se	spoel at gromacs.org   http://folding.bmc.uu.se
++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++++



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