[gmx-users] .top file from .gro file

sunny mishra mishra.sunny at gmail.com
Wed Aug 19 02:18:48 CEST 2009


Ok..I will see that and let you know. Thanks for the help though.
Sunny

On Tue, Aug 18, 2009 at 8:12 PM, Mark Abraham <Mark.Abraham at anu.edu.au>wrote:

> sunny mishra wrote:
>
>> I did the same but again i get the same error..something like this
>>
>> awk -f atom2cg_v2.1tryout.awk 1K4C.pdb > 1K4C_cg.pdb
>>
>> (This generated 1K4C_cg.pdb file)
>>
>> genbox -cp 1K4C_cg.pdb -box 10 10 10 -o 1K4C_cg.gro
>>
>> (produced 1K4C_cg.gro)
>>
>> GROningen MAchine for Chemical Simulation
>>
>>                            :-)  VERSION 4.0.5  (-:
>>
>>
>>      Written by David van der Spoel, Erik Lindahl, Berk Hess, and others.
>>       Copyright (c) 1991-2000, University of Groningen, The Netherlands.
>>             Copyright (c) 2001-2008, The GROMACS development team,
>>            check out http://www.gromacs.org for more information.
>>
>>         This program is free software; you can redistribute it and/or
>>          modify it under the terms of the GNU General Public License
>>         as published by the Free Software Foundation; either version 2
>>             of the License, or (at your option) any later version.
>>
>>                                :-)  genbox  (-:
>>
>> Option     Filename  Type         Description
>> ------------------------------------------------------------
>>  -cp    1K4C_cg.pdb  Input, Opt!  Structure file: gro g96 pdb tpr tpb tpa
>>  -cs     spc216.gro  Input, Opt., Lib. Structure file: gro g96 pdb tpr tpb
>> tpa
>>  -ci     insert.gro  Input, Opt.  Structure file: gro g96 pdb tpr tpb
>> tpa
>>  -o    1K4C_cg.gro  Output       Structure file: gro g96
>> pdb
>>  -p      topol.top  In/Out, Opt. Topology
>> file
>>
>> Option       Type   Value   Description
>> ------------------------------------------------------
>> -[no]h       bool   no      Print help info and quit
>> -nice        int    19      Set the nicelevel
>> -box         vector 10 10 10  box size
>> -nmol        int    0       no of extra molecules to insert
>> -try         int    10      try inserting -nmol*-try times
>> -seed        int    1997    random generator seed
>> -vdwd        real   0.105   default vdwaals distance
>> -shell       real   0       thickness of optional water layer around
>> solute
>> -maxsol      int    0       maximum number of solvent molecules to add if
>>                            they fit in the box. If zero (default) this is
>>                            ignored
>> -[no]vel     bool   no      keep velocities from input solute and solvent
>>
>> Opening library file /usr/local/gromacs/share/gromacs/top/aminoacids.dat
>> WARNING: masses will be determined based on residue and atom names,
>>         this can deviate from the real mass of the atom type
>> Opening library file /usr/local/gromacs/share/gromacs/top/atommass.dat
>> Entries in atommass.dat: 178
>> WARNING: vdwradii will be determined based on residue and atom names,
>>         this can deviate from the real mass of the atom type
>> Opening library file /usr/local/gromacs/share/gromacs/top/vdwradii.dat
>> Entries in vdwradii.dat: 28
>> Opening library file /usr/local/gromacs/share/gromacs/top/dgsolv.dat
>> Entries in dgsolv.dat: 7
>> Opening library file /usr/local/gromacs/share/gromacs/top/electroneg.dat
>> Entries in electroneg.dat: 71
>> Opening library file /usr/local/gromacs/share/gromacs/top/elements.dat
>> Entries in elements.dat: 218
>> Reading solute configuration
>> MEMBRANE PROTEIN
>> Containing 1127 atoms in 534 residues
>> Initialising van der waals distances...
>> Writing generated configuration to 1K4C_cg.gro
>> MEMBRANE PROTEIN
>>
>> Output configuration contains 1127 atoms in 534 residues
>> Volume                 :        1000 (nm^3)
>> Density                :     53.8545 (g/l)
>> Number of SOL molecules:      0
>>
>>
>> gcq#69: "I Want to Know Right Now" (Meatloaf)
>>
>>
>> After that ;;;;;;;;;;;;;;;;;;;;;;;
>>
>> grompp -f em.mdp -c 1K4C_cg.gro -p 1K4C.top -maxwarn 10
>>
>>                         :-)  G  R  O  M  A  C  S
>> (-:
>>
>>             Gallium Rubidium Oxygen Manganese Argon Carbon Silicon
>>
>>                            :-)  VERSION 4.0.5  (-:
>>
>>
>>      Written by David van der Spoel, Erik Lindahl, Berk Hess, and others.
>>       Copyright (c) 1991-2000, University of Groningen, The Netherlands.
>>             Copyright (c) 2001-2008, The GROMACS development team,
>>            check out http://www.gromacs.org for more information.
>>
>>         This program is free software; you can redistribute it and/or
>>          modify it under the terms of the GNU General Public License
>>         as published by the Free Software Foundation; either version 2
>>             of the License, or (at your option) any later version.
>>
>>                                :-)  grompp  (-:
>>
>> Option     Filename  Type         Description
>> ------------------------------------------------------------
>>  -f         em.mdp  Input, Opt!  grompp input file with MD parameters
>>  -po      mdout.mdp  Output       grompp input file with MD parameters
>>  -c    1K4C_cg.gro  Input        Structure file: gro g96 pdb tpr tpb tpa
>>  -r       conf.gro  Input, Opt.  Structure file: gro g96 pdb tpr tpb tpa
>>  -rb       conf.gro  Input, Opt.  Structure file: gro g96 pdb tpr tpb tpa
>>  -n      index.ndx  Input, Opt.  Index file
>>  -p       1K4C.top  Input        Topology file
>>  -pp  processed.top  Output, Opt. Topology file
>>  -o      topol.tpr  Output       Run input file: tpr tpb tpa
>>  -t       traj.trr  Input, Opt.  Full precision trajectory: trr trj cpt
>>  -e       ener.edr  Input, Opt.  Energy file: edr ene
>>
>> Option       Type   Value   Description
>> ------------------------------------------------------
>> -[no]h       bool   no      Print help info and quit
>> -nice        int    0       Set the nicelevel
>> -[no]v       bool   yes     Be loud and noisy
>> -time        real   -1      Take frame at or first after this time.
>> -[no]rmvsbds bool   yes     Remove constant bonded interactions with
>> virtual
>>                            sites
>> -maxwarn     int    10      Number of allowed warnings during input
>> processing
>> -[no]zero    bool   no      Set parameters for bonded interactions
>> without
>>                            defaults to zero instead of generating an
>> error
>> -[no]renum   bool   yes     Renumber atomtypes and minimize number
>> of
>>
>> atomtypes
>>
>> Ignoring obsolete mdp entry 'title'
>> Ignoring obsolete mdp entry 'cpp'
>> Replacing old mdp entry 'unconstrained_start' by 'continuation'
>>
>> Back Off! I just backed up mdout.mdp to ./#mdout.mdp.9#
>> checking input for internal consistency...
>>
>> NOTE 1 [file em.mdp, line unknown]:
>>  For energy conservation with switch/shift potentials, rlist should be 0.1
>>  to 0.3 nm larger than rcoulomb.
>>
>>
>> NOTE 2 [file em.mdp, line unknown]:
>>  For energy conservation with switch/shift potentials, rlist should be 0.1
>>  to 0.3 nm larger than rvdw.
>>
>> processing topology...
>> Generated 0 of the 465 non-bonded parameter combinations
>> Excluding 1 bonded neighbours molecule type 'Protein'
>>
>> NOTE 3 [file 1K4C.top, line 15]:
>>  System has non-zero total charge: 4.000000e+00
>>
>>
>>
>> processing coordinates...
>>
>> -------------------------------------------------------
>> Program grompp, VERSION 4.0.5
>> Source code file: grompp.c, line: 362
>>
>> Fatal error:
>> number of coordinates in coordinate file (1K4C_cg.gro, 1127)
>>             does not match topology (1K4C.top, 1166)
>> -------------------------------------------------------
>>
>
> That's a pretty explicit error message. Go and look at the molecule and
> atom ordering in the two files and see where they don't match.
>
> Mark
>
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