[gmx-users] water simulation

abhijit kayal kayalabhijitiitd at gmail.com
Tue Aug 25 13:05:49 CEST 2009


Hi,
With my grompp.mdp,topol.top and gonf.gro i gave the command and the output
was
[abhijit at SCFBioServer gromacs]$ grompp -f grompp.mdp  -p topol.top -c
conf.gro -o water.tpr
                         :-)  G  R  O  M  A  C  S  (-:

                Gravel Rubs Often Many Awfully Cauterized Sores

                            :-)  VERSION 4.0.4  (-:


      Written by David van der Spoel, Erik Lindahl, Berk Hess, and others.
       Copyright (c) 1991-2000, University of Groningen, The Netherlands.
             Copyright (c) 2001-2008, The GROMACS development team,
            check out http://www.gromacs.org for more information.

         This program is free software; you can redistribute it and/or
          modify it under the terms of the GNU General Public License
         as published by the Free Software Foundation; either version 2
             of the License, or (at your option) any later version.

                                :-)  grompp  (-:

Option     Filename  Type         Description
------------------------------------------------------------
  -f     grompp.mdp  Input, Opt!  grompp input file with MD parameters
 -po      mdout.mdp  Output       grompp input file with MD parameters
  -c       conf.gro  Input        Structure file: gro g96 pdb tpr tpb tpa
  -r       conf.gro  Input, Opt.  Structure file: gro g96 pdb tpr tpb tpa
 -rb       conf.gro  Input, Opt.  Structure file: gro g96 pdb tpr tpb tpa
  -n      index.ndx  Input, Opt.  Index file
  -p      topol.top  Input        Topology file
 -pp  processed.top  Output, Opt. Topology file
  -o      water.tpr  Output       Run input file: tpr tpb tpa
  -t       traj.trr  Input, Opt.  Full precision trajectory: trr trj cpt
  -e       ener.edr  Input, Opt.  Energy file: edr ene

Option       Type   Value   Description
------------------------------------------------------
-[no]h       bool   no      Print help info and quit
-nice        int    0       Set the nicelevel
-[no]v       bool   yes     Be loud and noisy
-time        real   -1      Take frame at or first after this time.
-[no]rmvsbds bool   yes     Remove constant bonded interactions with virtual
                            sites
-maxwarn     int    0       Number of allowed warnings during input
processing
-[no]zero    bool   no      Set parameters for bonded interactions without
                            defaults to zero instead of generating an error
-[no]renum   bool   yes     Renumber atomtypes and minimize number of
                            atomtypes

Ignoring obsolete mdp entry 'cpp'
checking input for internal consistency...

NOTE 1 [file grompp.mdp, line unknown]:
  The Berendsen thermostat does not generate the correct kinetic energy
  distribution. You might want to consider using the V-rescale thermostat.

processing topology...

-------------------------------------------------------
Program grompp, VERSION 4.0.4
Source code file: topio.c, line: 415

Fatal error:
Syntax error - File topol.top, line 4
Last line read:
'[ atomtypes ]'
Invalid order for directive atomtypes
-------------------------------------------------------

"I believe in miracles cause I'm one" (The Ramones)
[abhijit at SCFBioServer gromacs]$
 my topol.top file is
xirs    fudgeLJ fudgeQQ
1               2               yes             0.5     0.5
[ atomtypes ]
;name  at.num   mass       charge   ptype   sigma   epsilon
  OW    8       15.99940   0.000    A       0.3166    0.65
  HW    1        1.00800   0.000    A       0.00000E+00   0.00000E+00

;---------------------------------------------------------------
; Definition of the SPC/E water model---------------------------
;
[ moleculetype ]
; molname       nrexcl
SOL             2
[ atoms ]
;   nr   type  resnr residue  atom   cgnr     charge       mass
     1     OW      1    SOL     OW      1    -0.8476
     2     HW      1    SOL    HW1      1     0.4238
     3     HW      1    SOL    HW2      1     0.4238
[ settles ]
; OW    funct   doh     dhh
1       1       0.1     0.16330
[ exclusions ]
1       2       3
2       1       3
3       1       2
;---------------------------------------------------------------
; End of definition of the SPC/E water model--------------------
;---------------------------------------------------------------

[ system ]
Water SPC/E
[ molecules ]
SOL         216

the conf.gro file is
  203SOL    HW1  608   1.821   0.322   0.817  0.8928  1.1548  0.7389
  203SOL    HW2  609   1.875   0.440   0.718 -1.9604  0.3767 -1.7905
  204SOL     OW  610   0.779   1.345   0.916  0.2112 -0.0070  0.2315
  204SOL    HW1  611   0.686   1.338   0.954  0.8109 -1.6887  1.4414
  204SOL    HW2  612   0.805   1.442   0.909 -2.0435  0.5275 -1.1795
  205SOL     OW  613   1.718   1.114   0.507  0.2154 -0.1127 -0.1792
  205SOL    HW1  614   1.755   1.098   0.416 -0.9406 -0.2600 -0.6191
  205SOL    HW2  615   1.769   1.060   0.574 -1.8561 -3.6296 -1.3196
  206SOL     OW  616   0.694   0.641   1.677  0.0172  0.0058 -0.2012
  206SOL    HW1  617   0.784   0.654   1.717  1.2820 -2.2353 -2.2392
  206SOL    HW2  618   0.647   0.566   1.723 -1.1125  1.6018  1.2995
  207SOL     OW  619   1.089   0.525   0.672  0.1215 -0.1196 -0.1599
  207SOL    HW1  620   1.124   0.538   0.579  0.9751  2.2078  0.4622
  207SOL    HW2  621   0.995   0.490   0.668 -1.9486  5.2441 -2.0093
  208SOL     OW  622   1.644   0.521   0.536  0.8695 -0.0305  0.4538
  208SOL    HW1  623   1.568   0.521   0.602  1.0461 -0.1378  0.6487
  208SOL    HW2  624   1.683   0.429   0.530  0.6027 -0.1103 -0.0867
  209SOL     OW  625   1.607   0.804   1.136  0.1924 -0.0775 -0.0451
  209SOL    HW1  626   1.700   0.841   1.138 -0.3765  1.4071 -1.2113
  209SOL    HW2  627   1.602   0.725   1.198  1.8134  0.8052  1.2429
  210SOL     OW  628   0.961   1.176   0.727  0.0667  0.1065  0.0824
  210SOL    HW1  629   0.878   1.218   0.765  0.0936 -0.8745  1.2584
  210SOL    HW2  630   0.959   1.078   0.744  0.3982 -0.2571 -1.9273
  211SOL     OW  631   1.441   1.835   1.811  0.4461 -0.3668 -0.0023
  211SOL    HW1  632   1.478   1.796   1.727 -1.1085 -1.3547 -0.2480
  211SOL    HW2  633   1.442   1.766   1.884 -1.2578 -0.5603 -0.1372
  212SOL     OW  634   0.594   0.650   0.961  0.1032  0.4852  0.5329
  212SOL    HW1  635   0.642   0.644   1.049  0.6450 -0.1007  0.1907
  212SOL    HW2  636   0.660   0.659   0.887 -0.3688  1.3618  0.2061
  213SOL     OW  637   1.227   1.503   0.161 -0.0292 -0.8161  0.3425
  213SOL    HW1  638   1.225   1.458   0.251  0.3570 -0.7808  0.3667
  213SOL    HW2  639   1.136   1.535   0.138 -0.2322 -1.2929  0.4912
  214SOL     OW  640   0.606   0.647   1.408 -0.1516 -0.3989  0.3259
  214SOL    HW1  641   0.639   0.672   1.499 -1.3540  1.1041  0.3654
  214SOL    HW2  642   0.591   0.548   1.404  2.9386 -0.9536  0.7368
  215SOL     OW  643   1.607   1.679   0.596  0.1020 -0.0876  0.2788
  215SOL    HW1  644   1.558   1.743   0.537 -1.2519 -2.7009 -1.5800
  215SOL    HW2  645   1.542   1.635   0.658  0.9367  0.0657  1.2497
  216SOL     OW  646   1.663   1.409   0.500  0.3668  0.1318  0.2586
  216SOL    HW1  647   1.652   1.490   0.558  0.1481  1.3472 -1.4439
  216SOL    HW2  648   1.644   1.327   0.554  0.0397  1.2345  1.8708
   1.85058   1.85058   1.85058
and thegrompp.mdpo file is
tc-grps                  = System
tau_t                    = 0.1
ref_t                    = 300
Pcoupl                   = No
gen_vel                  = yes
gen_temp                 = 300
gen_seed                 = 1993
PCE model
cpp                      = /usr/bin/cpp
include                  =
define                   =
integrator               = md
dt                       = 0.001
nsteps                   = 50000
nstxtcout                = 100
xtc-precision            = 1000
rlist                    = 0.9
coulombtype              = Cut-off
rcoulomb                 = 0.9
vdw-type                 = Cut-off
rvdw                     = 0.9
DispCorr                 = EnerPres
Tcoupl                   = berendsen
tc-grps                  = System
tau_t                    = 0.1
ref_t                    = 300
Pcoupl                   = No
gen_vel                  = yes
gen_temp                 = 300
gen_seed                 = 1993:x
 so what is the problem

Abhijit Kayal
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