[gmx-users] essential dynamics mdrun with SD integrator yields segmentation fault

chris.neale at utoronto.ca chris.neale at utoronto.ca
Sat Dec 19 02:09:37 CET 2009


Hello,

In my hands, mdrun throws a segfault when passing the -ei flag to  
mdrun and utilizing the sd integrator. I'll admit that I have only  
tried this with a single system. Nevertheless, using -linacc vs.  
-linfix makes no difference, neither does moving to constraints=none  
or parallel vs. serial mdrun. However, when I change sd to md, the run  
is fine.

With sd and -ei, the segfault is immediate:

$ mdrun -deffnm edi -nosum -dlb yes -npme -1 -cpt 30 -maxh 48 -cpi  
edi.cpt -ei testpositive.edi -eo testpositive.edo
                          :-)  G  R  O  M  A  C  S  (-:

                       GROup of MAchos and Cynical Suckers

                             :-)  VERSION 4.0.5  (-:


       Written by David van der Spoel, Erik Lindahl, Berk Hess, and others.
        Copyright (c) 1991-2000, University of Groningen, The Netherlands.
              Copyright (c) 2001-2008, The GROMACS development team,
             check out http://www.gromacs.org for more information.

          This program is free software; you can redistribute it and/or
           modify it under the terms of the GNU General Public License
          as published by the Free Software Foundation; either version 2
              of the License, or (at your option) any later version.

                                 :-)  mdrun  (-:

Option     Filename  Type         Description
------------------------------------------------------------
   -s        edi.tpr  Input        Run input file: tpr tpb tpa
   -o        edi.trr  Output       Full precision trajectory: trr trj cpt
   -x        edi.xtc  Output, Opt. Compressed trajectory (portable xdr format)
-cpi        edi.cpt  Input, Opt!  Checkpoint file
-cpo        edi.cpt  Output, Opt. Checkpoint file
   -c        edi.gro  Output       Structure file: gro g96 pdb
   -e        edi.edr  Output       Energy file: edr ene
   -g        edi.log  Output       Log file
-dgdl       edi.xvg  Output, Opt. xvgr/xmgr file
-field      edi.xvg  Output, Opt. xvgr/xmgr file
-table      edi.xvg  Input, Opt.  xvgr/xmgr file
-tablep     edi.xvg  Input, Opt.  xvgr/xmgr file
-tableb     edi.xvg  Input, Opt.  xvgr/xmgr file
-rerun      edi.xtc  Input, Opt.  Trajectory: xtc trr trj gro g96 pdb cpt
-tpi        edi.xvg  Output, Opt. xvgr/xmgr file
-tpid       edi.xvg  Output, Opt. xvgr/xmgr file
  -ei testpositive.edi  Input, Opt!  ED sampling input
  -eo testpositive.edo  Output, Opt! ED sampling output
   -j        edi.gct  Input, Opt.  General coupling stuff
  -jo        edi.gct  Output, Opt. General coupling stuff
-ffout      edi.xvg  Output, Opt. xvgr/xmgr file
-devout     edi.xvg  Output, Opt. xvgr/xmgr file
-runav      edi.xvg  Output, Opt. xvgr/xmgr file
  -px        edi.xvg  Output, Opt. xvgr/xmgr file
  -pf        edi.xvg  Output, Opt. xvgr/xmgr file
-mtx        edi.mtx  Output, Opt. Hessian matrix
  -dn        edi.ndx  Output, Opt. Index file

Option       Type   Value   Description
------------------------------------------------------
-[no]h       bool   no      Print help info and quit
-nice        int    19      Set the nicelevel
-deffnm      string edi     Set the default filename for all file options
-[no]xvgr    bool   yes     Add specific codes (legends etc.) in the output
                             xvg files for the xmgrace program
-[no]pd      bool   no      Use particle decompostion
-dd          vector 0 0 0   Domain decomposition grid, 0 is optimize
-npme        int    -1      Number of separate nodes to be used for PME, -1
                             is guess
-ddorder     enum   interleave  DD node order: interleave, pp_pme or cartesian
-[no]ddcheck bool   yes     Check for all bonded interactions with DD
-rdd         real   0       The maximum distance for bonded interactions with
                             DD (nm), 0 is determine from initial coordinates
-rcon        real   0       Maximum distance for P-LINCS (nm), 0 is estimate
-dlb         enum   yes     Dynamic load balancing (with DD): auto, no or yes
-dds         real   0.8     Minimum allowed dlb scaling of the DD cell size
-[no]sum     bool   no      Sum the energies at every step
-[no]v       bool   no      Be loud and noisy
-[no]compact bool   yes     Write a compact log file
-[no]seppot  bool   no      Write separate V and dVdl terms for each
                             interaction type and node to the log file(s)
-pforce      real   -1      Print all forces larger than this (kJ/mol nm)
-[no]reprod  bool   no      Try to avoid optimizations that affect binary
                             reproducibility
-cpt         real   30      Checkpoint interval (minutes)
-[no]append  bool   no      Append to previous output files when continuing
                             from checkpoint
-[no]addpart bool   yes     Add the simulation part number to all output
                             files when continuing from checkpoint
-maxh        real   48      Terminate after 0.99 times this time (hours)
-multi       int    0       Do multiple simulations in parallel
-replex      int    0       Attempt replica exchange every # steps
-reseed      int    -1      Seed for replica exchange, -1 is generate a seed
-[no]glas    bool   no      Do glass simulation with special long range
                             corrections
-[no]ionize  bool   no      Do a simulation including the effect of an X-Ray
                             bombardment on your system

No previous checkpoint file present, assuming this is a new run.

ED sampling will be performed!

Reading file edi.tpr, VERSION 4.0.5 (single precision)
ED: Initialzing essential dynamics constraints.
ED: Reading edi file testpositive.edi
ED: Note: Reference and average structure are composed of the same  
atom indices.
ED: Found 1 ED dataset.
ED: Initial RMSD from reference after fit = 0.307421 nm (dataset #1)

WARNING: This run will generate roughly 6031 Mb of data

starting mdrun 'Generated by genbox'
5000 steps,      5.0 ps.
Segmentation fault

##############################

The message is a little more verbose when i run it in parallel:

...
...
ED: Initialzing essential dynamics constraints.
ED: Reading edi file testpositive.edi
ED: Note: Reference and average structure are composed of the same  
atom indices.
ED: Found 1 ED dataset.
ED: Initial RMSD from reference after fit = 0.307421 nm (dataset #1)
Making 1D domain decomposition 8 x 1 x 1

WARNING: This run will generate roughly 6031 Mb of data

starting mdrun 'Generated by genbox'
5000 steps,      5.0 ps.
[gpc-f103n048:05752] *** Process received signal ***
[gpc-f103n048:05752] Signal: Segmentation fault (11)
[gpc-f103n048:05752] Signal code: Address not mapped (1)
[gpc-f103n048:05752] Failing at address: 0x1abb0
[gpc-f103n048:05750] *** Process received signal ***
[gpc-f103n048:05750] Signal: Segmentation fault (11)
[gpc-f103n048:05750] Signal code: Address not mapped (1)
[gpc-f103n048:05750] Failing at address: 0x46398
[gpc-f103n048:05746] *** Process received signal ***
[gpc-f103n048:05746] Signal: Segmentation fault (11)
[gpc-f103n048:05746] Signal code: Address not mapped (1)
...
...

##############################

When I use md, however, things are fine.

Is there some reason that I should not be combining ED mdrun and the  
SD integrator? It seems like a reasonable combination to me and I was  
unable to find and documentation suggesting that one should not be  
doing this.

Thank you,
Chris.

PS: I repeated this with 4.0.7 and found the same behaviour:

$ /scratch/cneale/GPC/exe/intel/gromacs-4.0.7/exec/bin/mdrun -deffnm  
edi -nosum -dlb yes -npme -1 -cpt 30 -maxh 48 -cpi edi.cpt -ei  
testpositive.edi -eo testpositive.edo
                          :-)  G  R  O  M  A  C  S  (-:

                        Great Red Owns Many ACres of Sand

                             :-)  VERSION 4.0.7  (-:


       Written by David van der Spoel, Erik Lindahl, Berk Hess, and others.
        Copyright (c) 1991-2000, University of Groningen, The Netherlands.
              Copyright (c) 2001-2008, The GROMACS development team,
             check out http://www.gromacs.org for more information.

          This program is free software; you can redistribute it and/or
           modify it under the terms of the GNU General Public License
          as published by the Free Software Foundation; either version 2
              of the License, or (at your option) any later version.

       :-)  /scratch/cneale/GPC/exe/intel/gromacs-4.0.7/exec/bin/mdrun  (-:

Option     Filename  Type         Description
------------------------------------------------------------
   -s        edi.tpr  Input        Run input file: tpr tpb tpa
   -o        edi.trr  Output       Full precision trajectory: trr trj cpt
   -x        edi.xtc  Output, Opt. Compressed trajectory (portable xdr format)
-cpi        edi.cpt  Input, Opt!  Checkpoint file
-cpo        edi.cpt  Output, Opt. Checkpoint file
   -c        edi.gro  Output       Structure file: gro g96 pdb
   -e        edi.edr  Output       Energy file: edr ene
   -g        edi.log  Output       Log file
-dgdl       edi.xvg  Output, Opt. xvgr/xmgr file
-field      edi.xvg  Output, Opt. xvgr/xmgr file
-table      edi.xvg  Input, Opt.  xvgr/xmgr file
-tablep     edi.xvg  Input, Opt.  xvgr/xmgr file
-tableb     edi.xvg  Input, Opt.  xvgr/xmgr file
-rerun      edi.xtc  Input, Opt.  Trajectory: xtc trr trj gro g96 pdb cpt
-tpi        edi.xvg  Output, Opt. xvgr/xmgr file
-tpid       edi.xvg  Output, Opt. xvgr/xmgr file
  -ei testpositive.edi  Input, Opt!  ED sampling input
  -eo testpositive.edo  Output, Opt! ED sampling output
   -j        edi.gct  Input, Opt.  General coupling stuff
  -jo        edi.gct  Output, Opt. General coupling stuff
-ffout      edi.xvg  Output, Opt. xvgr/xmgr file
-devout     edi.xvg  Output, Opt. xvgr/xmgr file
-runav      edi.xvg  Output, Opt. xvgr/xmgr file
  -px        edi.xvg  Output, Opt. xvgr/xmgr file
  -pf        edi.xvg  Output, Opt. xvgr/xmgr file
-mtx        edi.mtx  Output, Opt. Hessian matrix
  -dn        edi.ndx  Output, Opt. Index file

Option       Type   Value   Description
------------------------------------------------------
-[no]h       bool   no      Print help info and quit
-nice        int    19      Set the nicelevel
-deffnm      string edi     Set the default filename for all file options
-[no]xvgr    bool   yes     Add specific codes (legends etc.) in the output
                             xvg files for the xmgrace program
-[no]pd      bool   no      Use particle decompostion
-dd          vector 0 0 0   Domain decomposition grid, 0 is optimize
-npme        int    -1      Number of separate nodes to be used for PME, -1
                             is guess
-ddorder     enum   interleave  DD node order: interleave, pp_pme or cartesian
-[no]ddcheck bool   yes     Check for all bonded interactions with DD
-rdd         real   0       The maximum distance for bonded interactions with
                             DD (nm), 0 is determine from initial coordinates
-rcon        real   0       Maximum distance for P-LINCS (nm), 0 is estimate
-dlb         enum   yes     Dynamic load balancing (with DD): auto, no or yes
-dds         real   0.8     Minimum allowed dlb scaling of the DD cell size
-[no]sum     bool   no      Sum the energies at every step
-[no]v       bool   no      Be loud and noisy
-[no]compact bool   yes     Write a compact log file
-[no]seppot  bool   no      Write separate V and dVdl terms for each
                             interaction type and node to the log file(s)
-pforce      real   -1      Print all forces larger than this (kJ/mol nm)
-[no]reprod  bool   no      Try to avoid optimizations that affect binary
                             reproducibility
-cpt         real   30      Checkpoint interval (minutes)
-[no]append  bool   no      Append to previous output files when continuing
                             from checkpoint
-[no]addpart bool   yes     Add the simulation part number to all output
                             files when continuing from checkpoint
-maxh        real   48      Terminate after 0.99 times this time (hours)
-multi       int    0       Do multiple simulations in parallel
-replex      int    0       Attempt replica exchange every # steps
-reseed      int    -1      Seed for replica exchange, -1 is generate a seed
-[no]glas    bool   no      Do glass simulation with special long range
                             corrections
-[no]ionize  bool   no      Do a simulation including the effect of an X-Ray
                             bombardment on your system

No previous checkpoint file present, assuming this is a new run.

ED sampling will be performed!

Back Off! I just backed up testpositive.edo to ./#testpositive.edo.4#
Reading file edi.tpr, VERSION 4.0.7 (single precision)
ED: Initialzing essential dynamics constraints.
ED: Reading edi file testpositive.edi
ED: Note: Reference and average structure are composed of the same  
atom indices.
ED: Found 1 ED dataset.
ED: Initial RMSD from reference after fit = 0.307421 nm (dataset #1)

WARNING: This run will generate roughly 6031 Mb of data

starting mdrun 'Generated by genbox'
5000 steps,      5.0 ps.
Segmentation fault






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