[gmx-users] handling particle decomposition with distance restraints

Justin A. Lemkul jalemkul at vt.edu
Thu Jun 25 03:53:16 CEST 2009



jayant james wrote:
> Yes my distance restraints are long because I am using FRET distances as 
> distance restraints while performing MD simulations. Upon usage of this 
> command
> 
> mpirun -np 4  mdrun_mpi  -s pr -e pr -g md -o traj.trr -c pr.gro  
> -pd       &
> 
> I get the following error!!   I did try giving yes after -pd but even 
> then the same error message is repeated.
> 

Anything else printed to the screen or log file?  LINCS warnings or anything 
else?  Did energy minimization complete successfully?

-Justin

> Back Off! I just backed up md.log to ./#md.log.9#
> Reading file pr.tpr, VERSION 4.0 (single precision)
> NNODES=4, MYRANK=1, HOSTNAME=localhost.localdomain
> NODEID=1 argc=13
> NODEID=3 argc=13
> [localhost:17514] *** Process received signal ***
> [localhost:17514] Signal: Segmentation fault (11)
> [localhost:17514] Signal code: Address not mapped (1)
> [localhost:17514] Failing at address: 0x1340000
> [localhost:17514] [ 0] /lib64/libpthread.so.0 [0x38dec0f0f0]
> [localhost:17514] [ 1] /lib64/libc.so.6(memcpy+0x15b) [0x38de08432b]
> [localhost:17514] [ 2] 
> /usr/lib64/openmpi/1.2.4-gcc/libmpi.so.0(ompi_convertor_pack+0x152) 
> [0x3886e45392]
> [localhost:17514] [ 3] 
> /usr/lib64/openmpi/1.2.4-gcc/openmpi/mca_btl_sm.so(mca_btl_sm_prepare_src+0x13d) 
> [0x7f39dd118a4d]
> [localhost:17514] [ 4] 
> /usr/lib64/openmpi/1.2.4-gcc/openmpi/mca_pml_ob1.so(mca_pml_ob1_send_request_start_rndv+0x140) 
> [0x7f39dd735230]
> [localhost:17514] [ 5] 
> /usr/lib64/openmpi/1.2.4-gcc/openmpi/mca_pml_ob1.so(mca_pml_ob1_send+0x748) 
> [0x7f39dd72e508]
> [localhost:17514] [ 6] 
> /usr/lib64/openmpi/1.2.4-gcc/openmpi/mca_coll_tuned.so(ompi_coll_tuned_bcast_intra_split_bintree+0x91c) 
> [0x7f39dc6f735c]
> [localhost:17514] [ 7] 
> /usr/lib64/openmpi/1.2.4-gcc/libmpi.so.0(MPI_Bcast+0x15c) [0x3886e4c40c]
> [localhost:17514] [ 8] mdrun_mpi(bcast_state+0x26c) [0x56d59c]
> [localhost:17514] [ 9] mdrun_mpi(mdrunner+0x1067) [0x42b807]
> [localhost:17514] [10] mdrun_mpi(main+0x3b4) [0x431c34]
> [localhost:17514] [11] /lib64/libc.so.6(__libc_start_main+0xe6) 
> [0x38de01e576]
> [localhost:17514] [12] mdrun_mpi [0x413339]
> [localhost:17514] *** End of error message ***
> mpirun noticed that job rank 0 with PID 17514 on node 
> localhost.localdomain exited on signal 11 (Segmentation fault).
> 3 additional processes aborted (not shown)
> 
> 
> 
> On Wed, Jun 24, 2009 at 6:04 PM, Justin A. Lemkul <jalemkul at vt.edu 
> <mailto:jalemkul at vt.edu>> wrote:
> 
> 
> 
>     jayant james wrote:
> 
> 
>         I just replaced the old gmx 4.0 version with the 4.0.5 version
>         and still the same problem
> 
>         NOTE: atoms involved in distance restraints should be within the
>         longest cut-off distance, if this is not the case mdrun
>         generates a fatal error, in that case use particle decomposition
>         (mdrun option -pd)  
> 
> 
>     Well, does it work with -pd?  It looks like your distance restraints
>     are indeed quite long, so this looks like it is your only option.
> 
>     -Justin
> 
> 
> 
>         WARNING: Can not write distance restraint data to energy file
>         with domain decomposition
> 
> 
> 
>         On Wed, Jun 24, 2009 at 5:10 PM, Justin A. Lemkul
>         <jalemkul at vt.edu <mailto:jalemkul at vt.edu>
>         <mailto:jalemkul at vt.edu <mailto:jalemkul at vt.edu>>> wrote:
> 
> 
> 
>            jayant james wrote:
> 
>                Hi!
>                I am performing an mpi MD (on a quad core system) run with
>                distance restraints. When I execute this command below
>          without
>                position restraints the MD run is distributed over 4 nodes
>                perfectly well. But when I incorporate the distance
>         restraints I
>                hit a road block
>                 mpirun -np 4  mdrun_mpi  -s pr -e pr -g md -o traj.trr
>         -c pr.gro  &
>                 I get this error message (below). My pr.mdp and distance
>                restraints files are given below the error message
>                . *
>                Question.* How do I handle this sitation? Do I increase
>         the long
>                range cut off in the pr.mdp file? If you see my distance
>                restraints file, my upper range of distances are close to
>         9nm!!
> 
> 
>            Upgrade to the latest version (4.0.5), since there have been
>            numerous improvements to domain decomposition throughout the
>            development of version 4.0.
> 
>            -Justin
> 
>                Please guide.
>                Thanks
>                JJ
>              
>          ----------------------------------------------------------------------------------------------------------------------------------------------------------
>                Back Off! I just backed up md.log to ./#md.log.6#
>                Reading file pr.tpr, VERSION 4.0 (single precision)
> 
>                NOTE: atoms involved in distance restraints should be
>         within the
>                longest cut-off distance, if this is not the case mdrun
>                generates a fatal error, in that case use particle
>         decomposition
>                (mdrun option -pd)                                      
>                                                                        
>                      
> 
>                WARNING: Can not write distance restraint data to energy file
>                with domain decomposition
> 
>                -------------------------------------------------------
>                Program mdrun_mpi, VERSION 4.0.2                      Source
>                code file: domdec.c, line: 5842                      
>          Fatal error:
>                There is no domain decomposition for 4 nodes that is
>         compatible
>                with the given box and a minimum cell size of 9.85926 nm
>                Change the number of nodes or mdrun option -rdd or -dds  
>                                                                        
>             Look in
>                the log file for details on the domain decomposition    
>                                                                        
>          
>          -----------------------------------------------------------------------------------------------------------------------------------------------
> 
>                *pr.mdp*
> 
>                ;       User spoel (236)
>                ;       Wed Nov  3 17:12:44 1993
>                ;       Input file
>                ;
>                title               =  Yo
>                cpp                 =  /usr/bin/cpp
>                define              =  -DDISRES
>                constraints         =  none
>                ;constraint_algorithm =  lincs
>                ;lincs_order         =  4
>                integrator          =  md
>                dt                  =  0.001    ; ps !
>                nsteps              =  4000000  ; total 2.0ns.
>                nstcomm             =  1
>                nstxout             =  50000
>                nstvout             =  50000
>                nstfout             =  50000
>                nstlog              =  50000
>                nstenergy           =  500
>                nstlist             =  10
>                ns_type             =  grid
>                rlist               =  1.0
>                coulombtype         =  PME
>                rcoulomb            =  1.0
>                vdwtype             =  cut-off
>                rvdw                =  1.4
>                fourierspacing      = 0.12
>                fourier_nx          = 0
>                fourier_ny          = 0
>                fourier_nz          = 0
>                pme_order           = 4
>                ewald_rtol          = 1e-5
>                optimize_fft        = yes
>                disre               =  simple
>                disre_weighting     =  equal
>                ; Berendsen temperature coupling is on in two groups
>                Tcoupl              =  V-rescale
>                tc-grps             =  Protein Non-Protein
>                tau_t               =  0.1 0.1
>                ref_t               =  300 300
>                ; Energy monitoring
>                energygrps          = Protein Non-Protein
>                ;tnc Non-Protein tnt NMR tni
>                ; Pressure coupling is not on
>                Pcoupl              =  parrinello-rahman
>                tau_p               =  0.5
>                compressibility     =  4.5e-5
>                ref_p               =  1.0
>                ;simulated annealing
>                ;Type of annealing form each temperature group
>         (no/single/periodic)
>                ;annealing          =   no, no, no, single, no
>                ;
>                ;Number of annealing points to use for specifying
>         annealing in
>                each group
>                ;annealing_npoints   =  0, 0, 0, 9, 0
>                ;
>                ; List of times at the annealing points for each group
>                ;annealing_time       =  0 25 50 75 100 125 150 175 200
>                ; Temp.at each annealing point, for each group.
>                ;annealing_temp      =  300 350 400 450 500 450 400 350 300
> 
>                *
>                 distance restraints file*
> 
>                 distance_restraints ]
>                ;       ai      aj      type    index   type'   low    
>         up1            up2     fac
>                ;TnT240-TnI131, 145, 151, 160, 167  (ca+-7)
>                       2019    3889    1       1       1       3.91  
>          3.91           5.31    0.574679
>                       2019    4056    1       2       1       4.86  
>          4.86           6.26    0.409911
>                       2019    4133    1       3       1       5.69  
>          5.69           7.09    0.457947
>                       2019    4207    1       4       1       6.63  
>          6.63           8.03    0.323852
>                       2019    4273    1       5       1       7.14  
>          7.14           8.54    0.294559
>                ;TnT276- Tni 131,145,151,160,167,5,17,27,40
>                       2434    3889    1       6       1       1.34  
>          1.34           2.74    4.884769
>                       2434    4056    1       7       1       2.13  
>          2.13           3.53    0.523368
>                       2434    4133    1       8       1       3.66  
>          3.66           5.06    0.409911
>                       2434    4207    1       9       1       4.48  
>          4.48           5.88    0.547825
>                       2434    4273    1       10      1       5.43  
>          5.43           6.83    0.285938
>                       2434    2628    1       11      1       5.89  
>          5.89           7.29    0.241333
>                       2434    2719    1       12      1       4.76  
>          4.76           6.16    0.366358
>                       2434    2824    1       13      1       3.81  
>          3.81           5.21    0.644145
>                       2434    2972    1       14      1       3.10  
>          3.10           4.50    0.431009
>                ;TnT288- Tni 131,145,151,160,167,5,17,27,40
>                       2557    3889    1       15      1       1.89  
>          1.89           3.29    1.429688
>                       2557    4056    1       16      1       3.25  
>          3.25           4.65    0.32931
>                       2557    4133    1       17      1       4.44  
>          4.44           5.84    0.346847
>                       2557    4207    1       18      1       4.80  
>          4.80           6.20    0.275198
>                       2557    4273    1       19      1       5.84  
>          5.84           7.24    0.200744
>                       2557    2628    1       20      1       4.79  
>          4.79           6.19    1.046736
>                       2557    2719    1       21      1       5.06  
>          5.06           6.46    0.267659
>                ;       2557    2824    1       22      1
>                       2557    2972    1       23      1       3.99  
>          3.99           5.39    0.412797
> 
> 
> 
> 
> 
>              
>          ------------------------------------------------------------------------
> 
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> 
>            --    ========================================
> 
>            Justin A. Lemkul
>            Ph.D. Candidate
>            ICTAS Doctoral Scholar
>            Department of Biochemistry
>            Virginia Tech
>            Blacksburg, VA
>            jalemkul[at]vt.edu <http://vt.edu> <http://vt.edu> | (540)
>         231-9080
> 
>            http://www.bevanlab.biochem.vt.edu/Pages/Personal/justin
> 
>            ========================================
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> 
> 
>         -- 
>         Jayasundar Jayant James
> 
>         www.chick.com/reading/tracts/0096/0096_01.asp
>         <http://www.chick.com/reading/tracts/0096/0096_01.asp>
>         <http://www.chick.com/reading/tracts/0096/0096_01.asp>)
> 
> 
>     -- 
>     ========================================
> 
>     Justin A. Lemkul
>     Ph.D. Candidate
>     ICTAS Doctoral Scholar
>     Department of Biochemistry
>     Virginia Tech
>     Blacksburg, VA
>     jalemkul[at]vt.edu <http://vt.edu> | (540) 231-9080
>     http://www.bevanlab.biochem.vt.edu/Pages/Personal/justin
> 
>     ========================================
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> 
> 
> 
> -- 
> Jayasundar Jayant James
> 
> www.chick.com/reading/tracts/0096/0096_01.asp 
> <http://www.chick.com/reading/tracts/0096/0096_01.asp>)
> 

-- 
========================================

Justin A. Lemkul
Ph.D. Candidate
ICTAS Doctoral Scholar
Department of Biochemistry
Virginia Tech
Blacksburg, VA
jalemkul[at]vt.edu | (540) 231-9080
http://www.bevanlab.biochem.vt.edu/Pages/Personal/justin

========================================



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