[gmx-users] How to define "stretch" in ffoplsaabon.itp ?

Justin A. Lemkul jalemkul at vt.edu
Wed Mar 4 16:04:47 CET 2009



Tree wrote:
> Dear Justin:
> 
> 
> Thank you for your answer!!
> Yes, I found there is already a bond defined for CT and CT, meanwhile I 
> am waiting response from gmx-uses. 
> I deleted mine!
> 
> To confirm, I cannot avoid to ask you a question again.
> So, please let me explain...
> Sections [ bonds ], [pairs], [angles] and etc. in the "topol.top" show 
> the information on what interaction (and how) exist among atoms in those 
> sections.
> Real potential values are interpreted (assigned) when I run "grompp" to 
> get "tpr" file.
> --- Is this right?

Yes.

> 
> If this is right, I do not understand why I am not able to have new 
> "topol_new.top" file when I use "-pp topol_new.top" with "grompp".
> There is no error message...

It isn't produced?

> --- What does the "-pp" option generate when doing grompp-?
> 

The -pp option gives you a "processed" topology, explicitly showing every 
parameter that grompp assembled.

> Regarding the assignment of opls_xxx to atom type is, I think, well 
> described in the file, "csoplsaanb.itp".
> 

Is that some sort of modified form of ffoplsaanb.itp?  Often times a more 
detailed explanation is found in the .atp file for the corresponding force field.

-Justin

> Thank you again!
> 
> 
> Sincerely
> 
> C Kim
> 
> On Wed, Mar 4, 2009 at 9:47 AM, Justin A. Lemkul <jalemkul at vt.edu 
> <mailto:jalemkul at vt.edu>> wrote:
> 
> 
> 
>     Tree wrote:
> 
>         Dear All:
> 
> 
>         *[1 - Situation]*
>         I am trying to define "stretch" between two bonded atoms (for
>         example, in my system PE (polyethylene), C-C).
> 
>         *[2 - ffoplsaa.rtp file]*
>         In ffoplsaa.rtp file, I assigned   C1    >     opls_136
>           C2    >     opls_135
>         This can be done by my own idea, so it does not bother anything.
>         And totally okay.
> 
>         *[3 - opls_xxx and atom type]*
>         I found that the oplsaa interpret those "opls_xxx" atoms to atom
>         types (which are in ffoplsaabon.itp file) as follows,
>           opls_136     >     CT
>           opls_135     >     CT.
> 
>         ( from a file containing  opls_136   CT  6     12.01100  
>          -0.120       A    3.50000e-01  2.76144e-01
>          opls_137   CT  6     12.01100    -0.060       A    3.50000e-01
>          2.76144e-01
>         )
> 
>         *[4 - ffoplsaabon.itp]*
>         Based on the information in the section [2] and [3] above, I
>         added following two sentences in the ffoplsaabon.itp file.
> 
>           [ bondtypes ]
>           ; i    j  func       b0          kb
>             CT    CT      1    0.14900   334720.0   ;
> 
> 
>     There is already a CT-CT bond defined in ffoplsaabon.itp:
> 
>      CT    CT      1    0.15290   224262.4   ; CHARMM 22 parameter file
> 
>     If you don't want those parameters, make sure you comment out that
>     line so you know which parameters you are actually using!
> 
>         *[5 - pdb2gmx result]*
> 
>         Until the section [4], I have new ffoplsaabon.itp file, so I ran
>         pdb2gmx for my PE system.
>         After that, when I looked at the topology file (e.g. topol.top),
>         I could not find any information in the [ bonds ] section (after
>         the [ atoms ] section).
>         In other words, topol.top shows nothing in [ bonds ] section.
>             [ bonds ]
>             ;  ai    aj funct            c0            c1            c2
>                   c3
>                 1     2     1
> 
> 
>     It's not showing nothing.  Atoms 1 and 2 are bonded together.  As
>     long as there are parameters defined in ffoplsaabon.itp, then grompp
>     will interpret the topology correctly.  If grompp fails, then you
>     have identified a problem.
> 
>         *[6 - Question!]*
> 
>         I think my mistake came from section [3] or [4].
>           (1) Would you please let me know what I did wrong...?
> 
> 
>     Nothing so far that I can see (aside from potentially duplicating
>     parameters).
> 
> 
>           (2) If someone is familiar with defining stretch, angle,
>         dihedral and torsion in ffoplsaabon.itp, would you please give
>         me an idea on how-to?
> 
> 
>     How do you define "stretch"?  The force constant for how much the
>     bond length can deviate?  Otherwise, all bonded parameters are
>     assigned by pdb2gmx as long as all atom types are defined.
> 
> 
>           (3) Would you please summarize how the gromacs maps opls_xxx
>         with atom type (C, CT... etc)?
> 
> 
>     Read ffoplsaa.atp.
> 
>     -Justin
> 
>         *[7 - Thank you!]*
> 
>         Thank you so much your participation and help!!!
> 
> 
>         Sincerely,
> 
>         Kim
> 
> 
>         ------------------------------------------------------------------------
> 
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> 
>     -- 
>     ========================================
> 
>     Justin A. Lemkul
>     Graduate Research Assistant
>     ICTAS Doctoral Scholar
>     Department of Biochemistry
>     Virginia Tech
>     Blacksburg, VA
>     jalemkul[at]vt.edu <http://vt.edu> | (540) 231-9080
>     http://www.bevanlab.biochem.vt.edu/Pages/Personal/justin
> 
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> 
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-- 
========================================

Justin A. Lemkul
Graduate Research Assistant
ICTAS Doctoral Scholar
Department of Biochemistry
Virginia Tech
Blacksburg, VA
jalemkul[at]vt.edu | (540) 231-9080
http://www.bevanlab.biochem.vt.edu/Pages/Personal/justin

========================================



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