[gmx-users] analysis of md run results

Moeed lecielll at googlemail.com
Wed May 26 21:04:31 CEST 2010


Hello Justin,

The energy values I get differ mainly for LJ and coulomb(SR) terms. I read
through chapter 4 of manual but I did not find the difference between
LJ/coulomb 1-4  and SR.

1-Where can I read about the differences of these?
2-Do you think the difference in energies as a result of excluding
intramolecualr nonbonded interactions are reasonable?
3-I can not figure out why pressure in the first case in negative and it is
very large when exclusions are included.Also in the second case kinetic
energy is zero. :(
4-If I want to perform NPT simulation, the only thing I need to do is to
switch on Pcoupl option in mdp file?

Thank you for your help.

No exclusions: mdrun -s Hexane-Stack125_md.tpr -o Hexane-Stack125_md.tpr* -x
trajectoy.xtc *-c Hexane-Stack125_after_md -v >& output.mdrun_md

g_energy -f ener.edr -o energy.xvg:

tatistics over 5001 steps [ 0.0000 thru 10.0000 ps ], 13 data sets
The term 'Cons. rmsd ()' is averaged over 501 frames
All other averages are exact over 5001 steps

Energy                      Average       RMSD     Fluct.      Drift
Tot-Drift
-------------------------------------------------------------------------------
Angle                       4400.14    259.533    194.602    59.4737
594.856
Ryckaert-Bell.              1000.11    115.318    88.7683     25.494
254.991
LJ-14                         648.7    37.6872    36.5595    3.16904
31.6967
Coulomb-14                 -281.387    32.3948     12.468    10.3554
103.574
*LJ (SR)                    -3322.54    46.1011    40.9609    7.32669
73.2816
Coulomb (SR)                667.867    26.5968     9.4795   -8.60663
-86.0835*
Coul. recip.                921.791    26.6407    8.48573   -8.74618
-87.4793
*Potential                   4034.68    386.493    290.055     88.466
884.837*
Kinetic En.                 6336.76    250.507    237.567    27.5244
275.299
Total Energy                10371.4     561.13     450.23     115.99
1160.14
Temperature                 297.592    11.7645    11.1568    1.29262
12.9288
P*ressure (bar)             -37.0417    1165.58    1161.54   -33.5839
-335.906*
Cons. rmsd ()            3.74741e-06 2.92095e-07 2.34721e-07 6.02133e-08
6.02253e-07
Heat Capacity Cv:      12.5011 J/mol K (factor = 0.00156281)


run with exclusions in top file: mdrun -*rerun trajectoy.xtc* -s
Hexane-Stack125_md.tpr -o Hexane-Stack125_md.tpr -c Hexane-Stack125_after_md
-v >& output.mdrun_md

Statistics over 5001 steps [ 0.0000 thru 10.0000 ps ], 13 data sets
All averages are over 501 frames

Energy                      Average       RMSD     Fluct.      Drift
Tot-Drift
-------------------------------------------------------------------------------
Angle                       4400.09    284.259    237.268    54.2184
542.293
Ryckaert-Bell.              1009.62    124.468    94.0379    28.2417
282.474
LJ-14                       648.411    40.6844     39.926    2.70793
27.0848
Coulomb-14                 -278.654    34.4227    11.8071    11.1987
112.01
*LJ (SR)                    -3010.16     47.968    42.5388    7.67736
76.789
Coulomb (SR)                74.7846     2.5186    2.47007   0.170417
1.70451*
Coul. recip.               -78.0436    2.58606    1.54725  -0.717662
-7.17805
Potential                   2766.05    454.268    342.141    103.497
1035.18
Kinetic En.                       0          0          0
0          0
Total Energy                2766.05    454.268    342.141    103.497
1035.18
*Temperature                       0          0          0
0          0
Pressure (bar)              1973.01    177.068    172.803    13.3792
133.819*
Cons. rmsd ()                     0          0          0
0          0
Heat Capacity Cv:          nan J/mol K (factor = nan)

with: mdp file

        Electrostatics/VdW
coulombtype         =  PME
vdw-type            =  cut-off
;        Cut-offs
rlist               =  1.0
rcoulomb            =  1.0
rvdw                =  1.0

;        Temperature coupling    Berendsen temperature coupling is on in two
groups
Tcoupl              =  berendsen
tc-grps             =  HEX      ;sol
tau_t               =  0.1      ;0.1
ref_t               =  300      ;300

;        Pressure coupling:     Pressure coupling is not on
Pcoupl              =  no
tau_p               =  0.5
compressibility     =  4.5e-5
ref_p               =  1.0

;        Velocity generation    Generate velocites is on at 300 K. Manual
p155
gen_vel             =  yes
gen_temp            =  300.0
gen_seed            =  173529

;        Bonds
constraints         =  all-bonds
constraint-algorithm = lincs

pbc=xyz
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