[gmx-users] secondary structure propensities of residues

Mark Abraham Mark.Abraham at anu.edu.au
Tue Aug 16 01:37:37 CEST 2011


On 16/08/2011 7:04 AM, César Ávila wrote:
> I am using the latest vesion of DSSP (the one available at DSSP homepage)

So, as discussed in some thread to which I was referring, there have 
been some changes to DSSP that prior versions of GROMACS don't cope 
with. Until GROMACS updates, use a version of DSSP that's at least a 
year old.

Mark

>
> 2011/8/11 Mark Abraham <Mark.Abraham at anu.edu.au 
> <mailto:Mark.Abraham at anu.edu.au>>
>
>     On 10/08/2011 6:03 AM, César Ávila wrote:
>>     Hi,
>>     I downloaded release-4-5-patches from git. It compiles and
>>     installs successfully. Nevertheless I am getting a segmentation
>>     fault.
>
>     Are you using a version of DSSP that is compatible with GROMACS,
>     pre previous discussion of DSSP changes?
>
>     Mark
>
>
>>     With gdb I am getting the following messages
>>
>>
>>     gdb --args do_dssp -f ../0_trajout.xtc -s ../input/replica_0.tpr
>>     -ssdump data.dat -b 170000 -e 180000 -dt 10
>>     GNU gdb (GDB) 7.2-ubuntu
>>     Copyright (C) 2010 Free Software Foundation, Inc.
>>     License GPLv3+: GNU GPL version 3 or later
>>     <http://gnu.org/licenses/gpl.html>
>>     This is free software: you are free to change and redistribute it.
>>     There is NO WARRANTY, to the extent permitted by law.  Type "show
>>     copying"
>>     and "show warranty" for details.
>>     This GDB was configured as "x86_64-linux-gnu".
>>     Para las instrucciones de informe de errores, vea:
>>     <http://www.gnu.org/software/gdb/bugs/>...
>>     Leyendo símbolos desde /usr/local/gromacs/bin/do_dssp...(no se
>>     encontraron símbolos de depuración)hecho.
>>     (gdb) run
>>     Starting program: /usr/local/gromacs/bin/do_dssp -f
>>     ../0_trajout.xtc -s ../input/replica_0.tpr -ssdump data.dat -b
>>     170000 -e 180000 -dt 10
>>     [Depuración de hilo usando libthread_db enabled]
>>                              :-)  G  R  O  M  A  C  S  (-:
>>
>>                    Gromacs Runs One Microsecond At Cannonball Speeds
>>
>>                       :-)  VERSION 4.5.4-dev-20110803-e49fb5a  (-:
>>
>>             Written by Emile Apol, Rossen Apostolov, Herman J.C.
>>     Berendsen,
>>           Aldert van Buuren, Pär Bjelkmar, Rudi van Drunen, Anton
>>     Feenstra,
>>             Gerrit Groenhof, Peter Kasson, Per Larsson, Pieter
>>     Meulenhoff,
>>                Teemu Murtola, Szilard Pall, Sander Pronk, Roland Schulz,
>>                     Michael Shirts, Alfons Sijbers, Peter Tieleman,
>>
>>                    Berk Hess, David van der Spoel, and Erik Lindahl.
>>
>>            Copyright (c) 1991-2000, University of Groningen, The
>>     Netherlands.
>>                 Copyright (c) 2001-2010, The GROMACS development team at
>>             Uppsala University & The Royal Institute of Technology,
>>     Sweden.
>>                 check out http://www.gromacs.org for more information.
>>
>>              This program is free software; you can redistribute it
>>     and/or
>>               modify it under the terms of the GNU General Public License
>>              as published by the Free Software Foundation; either
>>     version 2
>>                  of the License, or (at your option) any later version.
>>
>>                         :-)  /usr/local/gromacs/bin/do_dssp  (-:
>>
>>     Option     Filename  Type         Description
>>     ------------------------------------------------------------
>>       -f ../0_trajout.xtc  Input        Trajectory: xtc trr trj gro
>>     g96 pdb cpt
>>       -s ../input/replica_0.tpr  Input        Structure+mass(db): tpr
>>     tpb tpa gro
>>                                        g96 pdb
>>       -n      index.ndx  Input, Opt.  Index file
>>     -ssdump    data.dat  Output, Opt! Generic data file
>>     -map         ss.map  Input, Lib.  File that maps matrix data to
>>     colors
>>       -o         ss.xpm  Output       X PixMap compatible matrix file
>>      -sc     scount.xvg  Output       xvgr/xmgr file
>>       -a       area.xpm  Output, Opt. X PixMap compatible matrix file
>>      -ta    totarea.xvg  Output, Opt. xvgr/xmgr file
>>      -aa   averarea.xvg  Output, Opt. xvgr/xmgr file
>>
>>     Option       Type   Value   Description
>>     ------------------------------------------------------
>>     -[no]h       bool   no      Print help info and quit
>>     -[no]version bool   no      Print version info and quit
>>     -nice        int    19      Set the nicelevel
>>     -b           time   170000  First frame (ps) to read from trajectory
>>     -e           time   180000  Last frame (ps) to read from trajectory
>>     -dt          time   10      Only use frame when t MOD dt = first
>>     time (ps)
>>     -tu          enum   ps      Time unit: fs, ps, ns, us, ms or s
>>     -[no]w       bool   no      View output .xvg, .xpm, .eps and .pdb
>>     files
>>     -xvg         enum   xmgrace  xvg plot formatting: xmgrace, xmgr
>>     or none
>>     -sss         string HEBT    Secondary structures for structure count
>>
>>     Reading file ../input/replica_0.tpr, VERSION 4.5.3 (single precision)
>>     Reading file ../input/replica_0.tpr, VERSION 4.5.3 (single precision)
>>
>>     Program received signal SIGSEGV, Segmentation fault.
>>     0x00007ffff6ae043c in gmx_strcasecmp () from
>>     /usr/local/gromacs/lib/libgmx.so.6
>>     (gdb) bt
>>     #0  0x00007ffff6ae043c in gmx_strcasecmp () from
>>     /usr/local/gromacs/lib/libgmx.so.6
>>     #1  0x00007ffff6ade68f in search_str () from
>>     /usr/local/gromacs/lib/libgmx.so.6
>>     #2  0x00007ffff7b508d4 in bPhobics () from
>>     /usr/local/gromacs/lib/libgmxana.so.6
>>     #3  0x000000000040309a in main ()
>>
>>
>>     2011/3/9 Mark Abraham <Mark.Abraham at anu.edu.au
>>     <mailto:Mark.Abraham at anu.edu.au>>
>>
>>         On 10/03/2011 1:36 AM, Justin A. Lemkul wrote:
>>
>>
>>
>>             ZHAO Lina wrote:
>>
>>                 Hi,
>>
>>                 How do get the percentage of the secondary structure
>>                 propensities of residues?
>>
>>                 seems dssp none such effect?
>>
>>
>>             The scout.xvg file contains everything you need (in a
>>             broad sense) - number of residues in a given secondary
>>             structure over time.  If you need a per-residue
>>             breakdown, there is no Gromacs tool that does that, but
>>             the .xpm file contains that information, so you can write
>>             your own script and extract it.
>>
>>
>>         Actually I modified do_dssp in late January to do that. The
>>         OP will need to download the release-4-5-patches version of
>>         src/tools/do_dssp.c and copy it to their normal installation
>>         directory (or compile release-4-5-patches).
>>
>>         Mark
>>
>>         -- 
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>>
>>
>>
>
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