[gmx-users] reg ionic strength effect on the given protein

[Justin A. Lemkul]

vidhya sankar wrote:
> Dear justin,
>                     Very very Thank you for witty and useful reply.
> I would like to study the effect of ionic strength on protein stability
>  Through SMD is it possible ? Can i correlate the result of SMD with 
> stability ?
>  Because  at high ionic strength The H-bonding between chains is 
> disrupted only hydrophobic interaction exists?
> 

SMD is a roundabout way to look at this.  At sufficiently high ionic strength, 
the protein may be destabilized in the absence of an applied force.

-Justin

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Justin A. Lemkul
Ph.D. Candidate
ICTAS Doctoral Scholar
MILES-IGERT Trainee
Department of Biochemistry
Virginia Tech
Blacksburg, VA
jalemkul[at]vt.edu | (540) 231-9080
http://www.bevanlab.biochem.vt.edu/Pages/Personal/justin

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