[gmx-users] Gromacs versions 4.0.5 and 4.5.4

Itamar Kass itamar.kass at monash.edu
Wed Oct 19 04:22:38 CEST 2011


Hi Sapna,

It is a good question, but such of personal preferences.  I found out that my simulations tend to crash more often when I am using 4.5.5. It might be the General-reaction -field I use or something else, I am not sure. Also, it seems I will not gain much from upgrading, so I stick to 4.0.7.

All this is not to say that 4.5.5 is not a good simulation package. It is a good and useful MD package, and I highly appreciate all the time and effort put into it.

Best,
Itamat

PS, there are still people around using 3.3.3 or even 3.2.1, so I am not that behind. 

On 19/10/2011, at 1:14 PM, Sapna Sarupria wrote:

> Dear Itamar,
> 
> Thank you for your response. Why did you prefer to stick to 4.0.7? Is there something particularly difficult to transfer from 4.0.7 version to 4.5 version?
> 
> Sapna
> 
> On Tue, Oct 18, 2011 at 9:36 PM, Itamar Kass <itamar.kass at monash.edu> wrote:
> Hi Sapna,
> 
> I had the same problem few weeks ago.
> 
> Apparently, some parameters are different (eg. nstpcouple).
> 
> Cheers,
> Itamar
> 
> PS I found out that I prefer to stick to 4.0.7.
> 
> 
> 
> 
> On 19/10/2011, at 12:08 PM, Sapna Sarupria wrote:
> 
>> Dear All,
>> 
>> I have a simulation set up for a mixture of carbon dioxide and water system which runs perfectly on Gromacs 4.0.5 version. I have run these simulations at different temperatures and pressures, from the same starting configuration and the simulation proceeds smoothly in the 4.0.5 version. However, when I use exactly the same files to run the simulation in 4.5.4 version, the system crashes and writes out several pdb files. I was wondering if there is anything specific that has been changed between the two versions. I have pasted the mdp file of the simulations below. Any input will be much appreciated.
>> 
>> MDP File 
>> 
>> title               =  100% occupancy CO2 hydrate ; a string
>> cpp               =  /lib/cpp                 ; c-preprocessor
>> dt                  =  0.002                    ; time step
>> nsteps          =  15000000                 ; number of steps
>> nstcomm      =  10                       ; reset c.o.m. motion
>> nstxout          =  0000                    ; write coords
>> nstvout          =  0000                    ; write velocities
>> nstlog             =  25000                    ; print to logfile
>> nstenergy       =  500                      ; print energies
>> xtc_grps          =  OW_HW1_HW2_CO2 
>> nstxtcout         =  1000
>> nstlist               =  10                       ; update pairlist
>> ns_type            =  grid                     ; pairlist method
>> coulombtype    =  PME
>> rvdw                  =  1.2                      ; cut-off for vdw
>> rcoulomb          =  1.2                      ; cut-off for coulomb
>> rlist                    =  1.2                      ; cut-off for coulomb
>> DispCorr          =  EnerPres
>> Tcoupl              =  Nose-Hoover
>> ref_t                  = 270 
>> tc-grps              =  System
>> tau_t                 =  0.5 
>> Pcoupl             =  Parrinello-Rahman
>> Pcoupltype      =  semiisotropic            ; pressure geometry
>> tau_p                =  1.0   1.0                ; p-coupoling time
>> compressibility   =  4.5e-5  4.5e-5           ; compressibility
>> ref_p                     =  30.5  30.5               ; ref pressure
>> gen_vel               =  yes                      ; generate initial vel
>> gen_temp             =  260                      ; initial temperature
>> gen_seed             =  372340                   ; random seed
>> constraint_algorithm = shake
>> constraints         =  all-bonds 
>> 
>> -------
>> 
>> 
>> Thank you,
>> 
>> Sincerely,
>> Sapna
>> -- 
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> 
> -----
> "In theory, there is no difference between theory and practice. But, in practice, there is." - Jan L.A. van de Snepscheut
> 
> ===========================================
> | Itamar Kass, Ph.D.
> | Postdoctoral Research Fellow
> |
> | Department of Biochemistry and Molecular Biology
> | Building 77 Clayton Campus
> | Wellington Road
> | Monash University,
> | Victoria 3800
> | Australia
> |
> | Tel: +61 3 9902 9376
> | Fax: +61 3 9902 9500
> | E-mail: Itamar.Kass at monash.edu
> ============================================
> 
> 
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> 
> 
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-----
"In theory, there is no difference between theory and practice. But, in practice, there is." - Jan L.A. van de Snepscheut

===========================================
| Itamar Kass, Ph.D.
| Postdoctoral Research Fellow
|
| Department of Biochemistry and Molecular Biology
| Building 77 Clayton Campus
| Wellington Road
| Monash University,
| Victoria 3800
| Australia
|
| Tel: +61 3 9902 9376
| Fax: +61 3 9902 9500
| E-mail: Itamar.Kass at monash.edu
============================================

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