[gmx-users] A query

Mark Abraham Mark.Abraham at anu.edu.au
Wed Feb 1 08:04:11 CET 2012


On 1/02/2012 4:19 PM, Anik Sen wrote:
> Hello,
> Am anik. Am using gromacs 4.5.5
>
> But the dna.rtp file contains the atom bname N3 under the residue file 
> DT. So whats the problem then.

Yes, that's the reason from the problem. Your input structure doesn't 
have that... I said:

> pdb2gmx can only match atom and residue names it finds in the topology 
> database (.rtp). Your input structure lacks a (correctly named) N3 
> atom in residue 31, which I think pdb2gmx looked for when building 
> hydrogen atoms.

*Your input structure* doesn't match the .rtp. You need to change the 
atom/residue naming of your input structure to conform.

Mark

>
> the dna.rtp file for DT
> [ DT ]
>  [ atoms ]
>    P      P             1.16590     1
>    O2     O1P          -0.77610     2
>    O2     O2P          -0.77610     3
>    OS     O5'          -0.49540     4
>    CT     C5'          -0.00690     5
>    H1     H5'1          0.07540     6
>    H1     H5'2          0.07540     7
>    CT     C4'           0.16290     8
>    H1     H4'           0.11760     9
>    OS     O4'          -0.36910    10
>    CT     C1'           0.06800    11
>    H2     H1'           0.18040    12
>    N*     N1           -0.02390    13
>    CM     C6           -0.22090    14
>    H4     H6            0.26070    15
>    CM     C5            0.00250    16
>    CT     C7           -0.22690    17
>    HC     H71           0.07700    18
>    HC     H72           0.07700    19
>    HC     H73           0.07700    20
>    C      C4            0.51940    21
>    O      O4           -0.55630    22
>    NA     N3           -0.43400    23
>    H      H3            0.34200    24
>    C      C2            0.56770    25
>    O      O2           -0.58810    26
>    CT     C3'           0.07130    27
>    H1     H3'           0.09850    28
>    CT     C2'          -0.08540    29
>    HC     H2'1          0.07180    30
>    HC     H2'2          0.07180    31
>    OS     O3'          -0.52320    32
>
> ------------------------------------------------------------------------
> *From:* gmx-users-bounces at gromacs.org [gmx-users-bounces at gromacs.org] 
> on behalf of Mark Abraham [Mark.Abraham at anu.edu.au]
> *Sent:* Tuesday, January 31, 2012 7:09 PM
> *To:* Discussion list for GROMACS users
> *Subject:* Re: [gmx-users] A query
>
> On 31/01/2012 9:04 PM, Anik Sen wrote:
>> Hello,
>> Am anik. Am using gromacs 4.5.5
>> I could not find the proper reason of the foillowig failure of my 
>> job. please help.
>>
>> *The following is a part of the dna pdb file, which I am using:
>>
>> *ATOM      1  O5'  DG5 X   1      13.663  36.760  21.465  0.00  0.00
>> ATOM      2  C1'  DG5 X   1      14.791  36.040  21.150  0.00  0.00
>> ATOM      3  C4'  DG5 X   1      14.771  34.703  21.873  0.00  0.00
>> ATOM      4  O4'  DG5 X   1      16.017  34.553  22.577  0.00  0.00
>> ATOM      5  C5'  DG5 X   1      13.724  34.528  22.970  0.00  0.00
>> ATOM      6  O3'  DG5 X   1      13.540  33.118  23.234  0.00  0.00
>> ATOM      7  C3'  DG5 X   1      14.362  35.323  24.108  0.00  0.00
>> ATOM      8  C2'  DG5 X   1      15.856  35.044  23.903  0.00  0.00
>> ATOM      9  N1   DG5 X   1      16.753  36.193  24.040  0.00  0.00
>> ATOM     10  C8  DG5 X   1      16.484  37.562  24.004  0.00  0.00
>> ATOM     11  N7  DG5 X   1      17.551  38.308  24.156  0.00  0.00
>> ATOM     12  C4  DG5 X   1      18.589  37.359  24.268  0.00  0.00
>> ATOM     13  C6  DG5 X   1      19.989  37.514  24.448  0.00  0.00
>> ATOM     14  O6  DG5 X   1      20.648  38.553  24.534  0.00  0.00
>> ATOM     15  N9  DG5 X   1      20.645  36.287  24.525  0.00  0.00
>> ATOM     16  C2  DG5 X   1      20.048  35.045  24.439  0.00  0.00
>> ATOM     17  N3  DG5 X   1      20.848  33.965  24.540  0.00  0.00
>> ATOM     18  N5  DG5 X   1      18.753  34.884  24.262  0.00  0.00
>> ATOM     19  C5  DG5 X   1      18.095  36.074  24.193  0.00  0.00
>> ATOM     20  P    DT   X   2      12.650  32.528  24.445  0.00  0.00
>> ATOM     21 O1P DT   X   2      12.016  31.284  23.943  0.00  0.00
>> ATOM     22 O2P DT   X   2      11.806  33.610  25.015  0.00  0.00
>> ATOM     23  O5' DT   X   2      13.743  32.102  25.531  0.00  0.00
>> ATOM     24  C3' DT   X   2      14.653  31.088  25.184  0.00  0.00
>> ATOM     25  C2' DT   X   2      15.813  31.114  26.126  0.00  0.00
>> ATOM     26  O3' DT   X   2      16.429  32.408  26.092  0.00  0.00
>> ATOM     27  C5' DT   X   2      15.420  30.906  27.570  0.00  0.00
>> ATOM     28  O4' DT   X   2      15.818  29.609  27.955  0.00  0.00
>> ATOM     29  C4' DT   X   2      16.171  31.996  28.340  0.00  0.00
>> ATOM     30  C1' DT   X   2      17.115  32.536  27.293  0.00  0.00
>> ATOM     31  N3  DT   X   2      17.425  33.937  27.428  0.00  0.00
>> ATOM     32  C2  DT   X   2      18.741  34.313  27.581  0.00  0.00
>> ATOM     33  O2  DT   X   2      19.667  33.515  27.649  0.00  0.00
>> ATOM     34  N1  DT   X   2      18.932  35.671  27.666  0.00  0.00 *
>>
>>
>> But my job is failing, as shown below:
>>
>>
>> *[ganguly at localhost anik]$ pdb2gmx -f dna-A.pdb -o dna-B.pdb -p topol.top
>>                          :-)  G  R  O  M  A  C  S  (-:
>>
>>                           GROtesk MACabre and Sinister
>>
>>                             :-)  VERSION 4.5.5  (-:
>>
>>         Written by Emile Apol, Rossen Apostolov, Herman J.C. Berendsen,
>>       Aldert van Buuren, Pär Bjelkmar, Rudi van Drunen, Anton Feenstra,
>>         Gerrit Groenhof, Peter Kasson, Per Larsson, Pieter Meulenhoff,
>>            Teemu Murtola, Szilard Pall, Sander Pronk, Roland Schulz,
>>                 Michael Shirts, Alfons Sijbers, Peter Tieleman,
>>
>> ...................................................................................
>> ...................................................................................
>> ...................................................................................
>>
>> Opening force field file 
>> /usr/local/gromacs/share/gromacs/top/amber03.ff/dna.arn
>> Opening force field file 
>> /usr/local/gromacs/share/gromacs/top/amber03.ff/rna.arn
>> Checking for duplicate atoms....
>> Now there are 657 atoms. Deleted 7 duplicates.
>>
>> -------------------------------------------------------
>> Program pdb2gmx, VERSION 4.5.5
>> Source code file: pgutil.c, line: 91
>>
>> Fatal error:
>> Atom N3 is used in an interaction of type atom in the topology
>> database, but an atom of that name was not found in residue
>> number 31
>
> pdb2gmx can only match atom and residue names it finds in the topology 
> database (.rtp). Your input structure lacks a (correctly named) N3 
> atom in residue 31, which I think pdb2gmx looked for when building 
> hydrogen atoms.
>
> Mark
>
>

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