[gmx-users] segmantation default

Justin A. Lemkul jalemkul at vt.edu
Thu Feb 2 16:03:03 CET 2012



mehmet kıytak wrote:
> hi Justin... you were right.. my equilibration is ınsufficient...ı 
> increase nsteps 50000....200000..now ı recieve this message..
> 
> Fatal error:
> The Z-size of the box (1.957000) times the triclinic skew factor 
> (1.000000) is smaller than the number of DD cells (2) times the smallest 
> allowed cell size (1.000000)
> 
> How can ı solve this problem...please help me...
> 

The error is still symptomatic of a crash.  Your box is distorting too much and 
various algorithms (most notably DD) are crashing.

-Justin

> 1 Şubat 2012 22:37 tarihinde Justin A. Lemkul <jalemkul at vt.edu 
> <mailto:jalemkul at vt.edu>> yazdı:
> 
> 
> 
>     mehmet kıytak wrote:
> 
>         hi justin
>         ı used this mdp. file ..simulation box may be wrong.?..ı used
>         dodecahedron distance edge 2.0 nm.....
> 
> 
>     No, that's almost certainly not the problem.  Insufficient
>     minimization/equilibration, or instability due to the use of the
>     free energy code is more likely.  You look to be trying to decouple
>     the entire system, which could be an unstable process.  You haven't
>     said what you're doing, so I won't hazard a guess at this point.
>      Please refer to the link I provided and try running without the
>     free energy code.  Otherwise, you're (potentially) trying to solve
>     several problems at once.
> 
>     -Justin
> 
>         ; Run control
>         integrator               = sd       ; Langevin dynamics
>         tinit                    = 0
>         dt                       = 0.002
>         nsteps                   = 2500000  ; 5 ns
>         nstcomm                  = 100
>         ; Output control
>         nstxout                  = 0
>         nstvout                  = 0
>         nstfout                  = 0
>         nstlog                   = 0
>         nstenergy                = 0
>         nstxtcout                = 0
>         xtc-precision            = 1000
>         ; Neighborsearching and short-range nonbonded interactions
>         nstlist                  = 10
>         ns_type                  = grid
>         pbc                      = xyz
>         rlist                    = 1.0
>         ; Electrostatics
>         coulombtype              = PME
>         rcoulomb                 = 1.0
>         ; van der Waals
>         vdw-type                 = switch
>         rvdw-switch              = 0.8
>         rvdw                     = 0.9
>         ; Apply long range dispersion corrections for Energy and Pressure
>         DispCorr                  = EnerPres
>         ; Spacing for the PME/PPPM FFT grid
>         fourierspacing           = 0.12
>         ; EWALD/PME/PPPM parameters
>         pme_order                = 6
>         ewald_rtol               = 1e-06
>         epsilon_surface          = 0
>         optimize_fft             = no
>         ; Temperature coupling
>         ; tcoupl is implicitly handled by the sd integrator
>         tc_grps                  = system
>         tau_t                    = 1.0
>         ref_t                    = 300
>         ; Pressure coupling is on for NPT
>         Pcoupl                   = Parrinello-Rahman
>         tau_p                    = 0.5
>         compressibility          = 4.5e-05
>         ref_p                    = 1.0
>         ; Free energy control stuff
>         free_energy              = yes
>         init_lambda              = 0.0
>         delta_lambda             = 0
>         foreign_lambda           = 0.05
>         sc-alpha                 = 0.5
>         sc-power                 = 1.0
>         sc-sigma                 = 0.3
>         couple-moltype           = system  ; name of moleculetype to
>         decouple
>         couple-lambda0           = vdw      ; only van der Waals
>         interactions
>         couple-lambda1           = none     ; turn off everything, in
>         this case only vdW
>         couple-intramol          = no
>         nstdhdl                  = 10
>         ; Do not generate velocities
>         gen_vel                  = no
>         ; options for bonds
>         constraints              = h-bonds  ; we only have C-H bonds here
>         ; Type of constraint algorithm
>         constraint-algorithm     = lincs
>         ; Constrain the starting configuration
>         ; since we are continuing from NPT
>         continuation             = yes
>         ; Highest order in the expansion of the constraint coupling matrix
>         lincs-order              = 12
> 
> 
>         1 Şubat 2012 19:41 tarihinde Justin A. Lemkul <jalemkul at vt.edu
>         <mailto:jalemkul at vt.edu> <mailto:jalemkul at vt.edu
>         <mailto:jalemkul at vt.edu>>> yazdı:
> 
> 
> 
> 
>            mehmet kıytak wrote:
> 
>                hi all...
>                ı have a problem.. ı got segmentation fault when run nvt
>                equilibration.. ı use below mdp file
> 
> 
>            Please post a complete .mdp file.  The Unix 'cat' command can be
>            used to print the contents of the text file, which can then be
>            copied and pasted into an email.
> 
> 
> 
>                couple-lambda0           = vdw      ; only van der Waals
>                interactions
>                couple-lambda1           = none     ; turn off everything, in
>                this case only vdW
>                couple-intramol          = no
>                nstdhdl                  = 10
> 
> 
>            It appears you are trying to do a free energy calculation by
>            transforming your system.  Turn off the free energy code to
>            determine whether or not this is a source of the problem.
> 
>            <snip>
> 
> 
>                Step 3, time 0.006 (ps)  LINCS WARNING
>                relative constraint deviation after LINCS:
>                rms 0.337002, max 0.559171 (between atoms 1 and 4)
>                bonds that rotated more than 30 degrees:
>                 atom 1 atom 2  angle  previous, current, constraint length
>                     1      2   90.0    0.1006   0.1091      0.1000
>                     1      3   90.0    0.2058   0.1141      0.1000
>                     1      4   90.0    0.3028   0.1559      0.1000
> 
>                Back Off! I just backed up step3b_n3.pdb to
>         ./#step3b_n3.pdb.1#
> 
>                Back Off! I just backed up step3b_n4.pdb to
>         ./#step3b_n4.pdb.1#
> 
>                Back Off! I just backed up step3c_n2.pdb to
>         ./#step3c_n2.pdb.1#
> 
>                Back Off! I just backed up step3c_n3.pdb to
>         ./#step3c_n3.pdb.1#
> 
>                Back Off! I just backed up step3c_n4.pdb to
>         ./#step3c_n4.pdb.1#
>                Wrote pdb files with previous and current coordinates
>                Wrote pdb files with previous and current coordinates
>                Wrote pdb files with previous and current coordinates
>                Segmentation fault
>                mkiytak at babil:~
> 
>                PLEASE HELP ME...
> 
> 
>            LINCS warnings are the most common error reported to this list.
>             Please refer to the following pages for help:
> 
>          
>          http://www.gromacs.org/____Documentation/Errors#LINCS.____2fSETTLE.2fSHAKE_warnings
>         <http://www.gromacs.org/__Documentation/Errors#LINCS.__2fSETTLE.2fSHAKE_warnings>
> 
>          
>          <http://www.gromacs.org/__Documentation/Errors#LINCS.__2fSETTLE.2fSHAKE_warnings
>         <http://www.gromacs.org/Documentation/Errors#LINCS.2fSETTLE.2fSHAKE_warnings>>
> 
>            If you still can't find your answer, refer to the list
>         archive.  As
>            I said, such errors are commonly reported.  Surely you'll find
>            something useful.  The only thing that can be said right now
>         is that
>            your system is unstable.  Either you need better minimization or
>            equilibration (or both), your .mdp settings are incorrect, or the
>            free energy code is causing an instability (which is a symptom of
>            the first two points, it does not suggest the free energy code is
>            not working).
> 
>            -Justin
> 
>            --     ==============================____==========
> 
> 
>            Justin A. Lemkul
>            Ph.D. Candidate
>            ICTAS Doctoral Scholar
>            MILES-IGERT Trainee
>            Department of Biochemistry
>            Virginia Tech
>            Blacksburg, VA
>            jalemkul[at]vt.edu <http://vt.edu> <http://vt.edu> | (540)
>         231-9080 <tel:%28540%29%20231-9080>
>            <tel:%28540%29%20231-9080>
>            http://www.bevanlab.biochem.____vt.edu/Pages/Personal/justin
>         <http://vt.edu/Pages/Personal/justin>
>            <http://www.bevanlab.biochem.__vt.edu/Pages/Personal/justin
>         <http://www.bevanlab.biochem.vt.edu/Pages/Personal/justin>>
> 
>            ==============================____==========
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> 
>     -- 
>     ==============================__==========
> 
>     Justin A. Lemkul
>     Ph.D. Candidate
>     ICTAS Doctoral Scholar
>     MILES-IGERT Trainee
>     Department of Biochemistry
>     Virginia Tech
>     Blacksburg, VA
>     jalemkul[at]vt.edu <http://vt.edu> | (540) 231-9080
>     <tel:%28540%29%20231-9080>
>     http://www.bevanlab.biochem.__vt.edu/Pages/Personal/justin
>     <http://www.bevanlab.biochem.vt.edu/Pages/Personal/justin>
> 
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-- 
========================================

Justin A. Lemkul
Ph.D. Candidate
ICTAS Doctoral Scholar
MILES-IGERT Trainee
Department of Biochemistry
Virginia Tech
Blacksburg, VA
jalemkul[at]vt.edu | (540) 231-9080
http://www.bevanlab.biochem.vt.edu/Pages/Personal/justin

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