I made my box with Amber xleap command: solvatebox complex TIP3PBOX 15 So it is bug in xleap? -- View this message in context: http://gromacs.5086.x6.nabble.com/My-box-size-canges-somehow-tp5015721p5015759.html Sent from the GROMACS Users Forum mailing list archive at Nabble.com.