[gmx-users] Parameter suggestion for locating an Iron atom between two carbon ring and preventing system blow up

Sajjad Kavyani kavyani.sajjad at gmail.com
Sun Dec 25 15:54:51 CET 2016


Dear Mark,
That was my mistake not to mention that the EM/NVT/NPT was for the full
system (ferr+benz).
And also, with the -pforce 10000 in every NPT run, it was revealed that the
large forces were appeared on the ferrocene residue.
As in the EM step the maximum force cannot be taken to below zero values,
Is the ferrocene topology correct?
Is there a better way to keep ferrocene in the middle of the two rings?
Could you please take another look?

Regards
Sajjad

On Sun, Dec 25, 2016 at 11:46 AM, Mark Abraham <mark.j.abraham at gmail.com>
wrote:

> Hi,
>
> What would you expect to happen to a large box with mostly vacuum when it
> is coupled to a normal pressure? Should that be stable?
>
> Mark
>
> On Sun, 25 Dec 2016 09:18 Sajjad Kavyani <kavyani.sajjad at gmail.com> wrote:
>
> > Dear experts,
> >
> > I'm trying to simulate a box of benzene with 25~35 ferrocene
> (C5H5-Fe-C5H5)
> > in it.
> > I have the benzene itp, but in the case of ferrocene I have a problem to
> > choose suitable parameter.
> > Each parameters I tried for ferrocene lead the system to blow up.
> > EVEN in a empty box (6 6 6) with just 20 or 30 ferrocene (pure ferrocene)
> > my system blows up in just 40000 steps (time step = 0.002)
> > For pure ferrocene, energy minimization hardly reach forces below 1000
> and
> > just in the case of changing the Fe bonds from 1 to harmonic (type 6) I
> > could manage to get below zero potential values. But again it hardly
> > reaches below 1000!
> > - The procedure before blowing up was:
> > EM - NVT - NPT (in this step, blows up)
> > EM - NVT (with posre) - NPT (with posre) - NPT (no posre && in this step.
> > blows up)
> > - For t/p coupling the 'berendsen' method was utilized. And constraints
> was
> > set to 'none'.
> > The following is the itp for ferrocene was used.
> >
> > Is it correct to define 10 bonds to keep Fe in the middle of the two
> rings?
> > What should I do to prevent the blow up?
> >
> >
> > This is atomtype.itp of Fe2+:
> > [ atomtypes ]
> >
> >     Fe2+     6      55.84700     0.000 A    0.115816833358 0.0
> >
> > ######
> > And, this is the ferrocene itp (OPLS ff):
> >
> >
> > [ moleculetype ]
> > ; molname       nrexcl
> > FRC                 3
> >
> >
> > [ atoms ]
> > ;id    type     resnr  residu  a.name  cgnr  charge        mass
> >   1    opls_714  1    FRC       CP1    1     -0.356        12.01100
> >   2    opls_715  1    FRC       HP1    2      0.156         1.00800
> >   3    opls_714  1    FRC       CP2    3     -0.356        12.01100
> >   4    opls_715  1    FRC       HP2    4      0.156         1.00800
> >   5    opls_714  1    FRC       CP3    5     -0.356        12.01100
> >   6    opls_715  1    FRC       HP3    6      0.156         1.00800
> >   7    opls_714  1    FRC       CP4    7     -0.356        12.01100
> >   8    opls_715  1    FRC       HP4    8      0.156         1.00800
> >   9    opls_714  1    FRC       CP5    9     -0.356        12.01100
> >   10   opls_715  1    FRC       HP5    10     0.156         1.00800
> >   11   Fe2+      1    FRC       FeS    11     2.000        55.84700
> >   12   opls_714  1    FRC       CP6    12    -0.356        12.01100
> >   13   opls_715  1    FRC       HP6    13     0.156         1.00800
> >   14   opls_714  1    FRC       CP7    14    -0.356        12.01100
> >   15   opls_715  1    FRC       HP7    15     0.156         1.00800
> >   16   opls_714  1    FRC       CP8    16    -0.356        12.01100
> >   17   opls_715  1    FRC       HP8    17     0.156         1.00800
> >   18   opls_714  1    FRC       CP9    18    -0.356        12.01100
> >   19   opls_715  1    FRC       HP9    19     0.156         1.00800
> >   20   opls_714  1    FRC       CP0    20    -0.356        12.01100
> >   21   opls_715  1    FRC       HP0    21     0.156         1.00800
> >
> > [ bonds ]
> > ;  i     j     funct   length    force.c.
> > ;;CyclPen1
> >    1 2      1       0.105     307105.6
> >    1 3      1       0.138     392459.2
> >    3 4      1       0.105     307105.6
> >    3 5      1       0.138     392459.2
> >    5 6      1       0.105     307105.6
> >    5 7      1       0.138     392459.2
> >    7 8      1       0.105     307105.6
> >    7 9      1       0.138     392459.2
> >    9 10     1       0.105     307105.6
> >    9 1      1       0.138     392459.2
> > ;;CyclPen2
> >    12 13     1       0.105     307105.6
> >    12 14     1       0.138     392459.2
> >    14 15     1       0.105     307105.6
> >    14 16     1       0.138     392459.2
> >    16 17     1       0.105     307105.6
> >    16 18     1       0.138     392459.2
> >    18 19     1       0.105     307105.6
> >    18 20     1       0.138     392459.2
> >    20 21     1       0.105     307105.6
> >    20 12     1       0.138     392459.2
> > ;;Iron with carbons:
> >    11 1      6       0.202     300500
> >    11 3      6       0.202     300500
> >    11 5      6       0.202     300500
> >    11 7      6       0.202     300500
> >    11 9      6       0.202     300500
> >    11 12     6       0.202     300500
> >    11 14     6       0.202     300500
> >    11 16     6       0.202     300500
> >    11 18     6       0.202     300500
> >    11 20     6       0.202     300500
> >
> > [ angles ]
> > ; i     j k       funct     angle       force.c.
> > ;;CyclPen1
> >    1     3 5       2         108         10.0
> >    3     5 7       2         108         10.0
> >    5     7 9       2         108         10.0
> >    7     9 1       2         108         10.0
> >    9     1 3       2         108         10.0
> > ;;CyclPen2
> >    12     14 16       2         108         10.0
> >    14     16 18       2         108         10.0
> >    16     18 20       2         108         10.0
> >    18     20 12       2         108         10.0
> >    20     12 14       2         108         10.0
> > --
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