[gmx-users] topology

RAHUL SURESH drrahulsuresh at gmail.com
Tue Feb 28 09:24:39 CET 2017


This is my itp file(only a part)

I have highlighted two errors.. there are 19 such errors.
If I can know the reason for the error exactly it would be of a great help
to me.


[ atoms ]
;   nr       type  resnr residue  atom   cgnr     charge       mass
typeB    chargeB      massB
     1   opls_154      1    UNK      O      0     -0.580921
15.99940
     2   opls_154      1    UNK      O      0     -0.635654
15.99940
     3   opls_516      1    UNK      C      1     -0.112257
12.01100
     4   opls_516      1    UNK      C      2     -0.163224
12.01100
     5   opls_516      1    UNK      C      3      0.228741
12.01100
     6   opls_516      1    UNK      C      4     -0.304756
12.01100
     7   opls_516      1    UNK      C      5     -0.312217
12.01100
     8   opls_145      1    UNK      C      6      0.120569
12.01100
     9   opls_145      1    UNK      C      7      0.151897
12.01100
    10   opls_145      1    UNK      C      8      0.231044
12.01100
    11   opls_516      1    UNK      C      9     -0.401751
12.01100
    12   opls_516      1    UNK      C     10     -0.403094
12.01100
    13   opls_145      1    UNK      C     11     -0.150352
12.01100
    14   opls_145      1    UNK      C     12      0.193129
12.01100
    15   opls_145      1    UNK      C     13     -0.161115
12.01100
    16   opls_516      1    UNK      C     14     -0.471874
12.01100
    17   opls_145      1    UNK      C     15      0.100725
12.01100
    18   opls_145      1    UNK      C     16     -0.153943
12.01100
    19   opls_516      1    UNK      C     17     -0.330577
12.01100
    20   opls_516      1    UNK      C     18     -0.229875
12.01100
    21   opls_135      1    UNK      C     19     -0.229884
12.01100
    22   opls_135      1    UNK      C     20     -0.237230
12.01100
    23   opls_135      1    UNK      C     21     -0.404861
12.01100
    24   opls_140      1    UNK      H     21      0.135257
1.00800
    25   opls_140      1    UNK      H     21      0.154010
1.00800
    26   opls_140      1    UNK     2H     21      0.142643
1.00800
    27   opls_140      1    UNK     1H     21      0.133623
1.00800
    28   opls_140      1    UNK     2H     21      0.137323
1.00800
    29   opls_140      1    UNK     1H     21      0.167475
1.00800
    30   opls_140      1    UNK     1H     21      0.135348
1.00800
    31   opls_140      1    UNK     2H     21      0.153851
1.00800
    32   opls_140      1    UNK     3H     21      0.138487
1.00800
    33   opls_140      1    UNK     1H     21      0.137087
1.00800
    34   opls_140      1    UNK     2H     21      0.146500
1.00800
    35   opls_140      1    UNK     3H     21      0.148972
1.00800
    36   opls_140      1    UNK      H     21      0.103605
1.00800
    37   opls_140      1    UNK      H     21      0.127061
1.00800
    38   opls_140      1    UNK     1H     21      0.143100
1.00800
    39   opls_140      1    UNK     2H     21      0.137525
1.00800
    40   opls_140      1    UNK     3H     21      0.140672
1.00800
    41   opls_140      1    UNK      H     21      0.106416
1.00800
    42   opls_140      1    UNK     1H     21      0.134610
1.00800
    43   opls_140      1    UNK     2H     21      0.126890
1.00800
    44   opls_140      1    UNK     2H     21      0.132690
1.00800
    45   opls_140      1    UNK     1H     21      0.124796
1.00800
    46   opls_140      1    UNK      H     21      0.371894
1.00800
    47   opls_140      1    UNK     1H     21      0.120642
1.00800
    48   opls_140      1    UNK     2H     21      0.117792
1.00800
    49   opls_140      1    UNK     2H     21      0.125342
1.00800
    50   opls_140      1    UNK     1H     21      0.122930
1.00800
    51   opls_140      1    UNK     1H     21      0.130012
1.00800
    52   opls_140      1    UNK     2H     21      0.129674
1.00800
    53   opls_140      1    UNK     3H     21      0.131255
1.00800

[ bonds ]
;  ai    aj funct
    1     5     1    ;     O     C
    1    10     1    ;     O     C
    2    14     1    ;     O     C
    *2    46     1    ;     O     H*
    3     4     1    ;     C     C
    3     5     1    ;     C     C
    3     6     1    ;     C     C
    3    24     1    ;     C     H
    4     7     1    ;     C     C
    4     8     1    ;     C     C
    4    25     1    ;     C     H
    5    11     1    ;     C     C
    5    12     1    ;     C     C
    6    13     1    ;     C     C
    6    26     1    ;     C    2H
    6    27     1    ;     C    1H
    7     9     1    ;     C     C
    7    28     1    ;     C    2H
    7    29     1    ;     C    1H
    8    10     1    ;     C     C
    8    14     1    ;     C     C
    9    13     1    ;     C     C
    9    16     1    ;     C     C
   10    15     1    ;     C     C
   11    30     1    ;     C    1H
   11    31     1    ;     C    2H
   11    32     1    ;     C    3H
   12    33     1    ;     C    1H
   12    34     1    ;     C    2H
   12    35     1    ;     C    3H
   *13    36     1    ;     C     H*
   14    18     1    ;     C     C
   15    17     1    ;     C     C
   15    37     1    ;     C     H
   16    38     1    ;     C    1H
   16    39     1    ;     C    2H
   16    40     1    ;     C    3H
   17    18     1    ;     C     C
   17    19     1    ;     C     C
   18    41     1    ;     C     H
   19    20     1    ;     C     C
   19    42     1    ;     C    1H
   19    43     1    ;     C    2H
   20    21     1    ;     C     C
   20    44     1    ;     C    2H
   20    45     1    ;     C    1H
   21    22     1    ;     C     C
   21    47     1    ;     C    1H
   21    48     1    ;     C    2H
   22    23     1    ;     C     C
   22    49     1    ;     C    2H
   22    50     1    ;     C    1H
   23    51     1    ;     C    1H
   23    52     1    ;     C    2H
   23    53     1    ;     C    3H

On Tue, Feb 28, 2017 at 3:57 AM, Justin Lemkul <jalemkul at vt.edu> wrote:

>
>
> On 2/27/17 12:49 AM, RAHUL SURESH wrote:
>
>> I am explaining my issues regarding complex simulation.
>>
>> I have 200ns conformer(OPLS FF)
>>
>> I have generated my ligand gro and itp file.(Using topolgen1_1)
>>
>> I have edited my protein gro file and made it into complex file as per the
>> tutorials.
>>
>> I have made changes to my topol.top file.
>>
>> Now in my command for em.mdp I am getting 19 errors stating "NO DEFAULT
>> BOND TYPE, ANGLE TYPE, ETC."
>>
>> Can you guide me with this?
>>
>>
> This means the atom type assignment makes reference to bonded parameters
> that don't exist.  That means one of two things: (1) either the atom type
> assignment is incorrect, requiring manual correction (as the script warns
> you, as it makes a lot of assumptions and is therefore rather dumb
> sometimes) or (2) you simply have a molecule for which parameters do not
> exist, requiring manual parametrization.  For OPLS-AA, this requires QM
> calculations to get things like equilibrium geometries, vibrational
> frequencies, and dihedral potential energy scans.
>
>
> -Justin
>
> --
> ==================================================
>
> Justin A. Lemkul, Ph.D.
> Ruth L. Kirschstein NRSA Postdoctoral Fellow
>
> Department of Pharmaceutical Sciences
> School of Pharmacy
> Health Sciences Facility II, Room 629
> University of Maryland, Baltimore
> 20 Penn St.
> Baltimore, MD 21201
>
> jalemkul at outerbanks.umaryland.edu | (410) 706-7441
> http://mackerell.umaryland.edu/~jalemkul
>
> ==================================================
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-- 
*Regards,*
*Rahul Suresh*
*Research Scholar*
*Bharathiar University*
*Coimbatore*


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