[gmx-users] Coarse Grained (Empty space In water)

[Samieegohar, Mohammadreza]

Hello
I am ruining a nanoparticle inside water. I use coarse grained model for water and nanoparticle
My problem is:
When I run the system in NVT 298K , after some steps there is a empty area inside the water  (like a hole) while the initial structure has a good distribution for water molecules (P4).

May you help me to solve the problem ?

Thanks