[gmx-users] Fwd: Ionic liquid and CNTs

Alex nedomacho at gmail.com
Thu Jun 28 09:43:05 CEST 2018


Ah, that's a scary looking system. :)

Indeed, there are vacuum pockets, because the system has not been 
brought to correct pressure. All you have to do for your relaxation run 
is use a semiisotropic barostat (maybe Berendsen, but only for 
relaxation) with a realistic solvent compressibility in the Z-direction 
and zero compressibility in the XY-plane. Gromacs allows this rather 
easily. And run it for something like 5-10 ns, not 0.5 ns.

Alex


On 6/28/2018 1:30 AM, Candy Deck wrote:
> Hi Alex,
> Thanks for your answer ...
> Here is the pdb file of my system : https://files.fm/u/7crt2yd5
> Candy
>
> 2018-06-27 22:30 GMT+02:00 Alex <nedomacho at gmail.com>:
>
>> If there is a bubble, all it could mean is that the volume simply too
>> large, which could be expected, given the combination of short simulation
>> and low compressibility. It is also unclear what your system looks like.
>> Please upload your pdb or an image somewhere.
>>
>> Alex
>>
>> On Wed, Jun 27, 2018 at 3:47 AM, Candy Deck <candy.a.deck at gmail.com>
>> wrote:
>>
>>> Dear Gromacs Users.
>>> I started using Gromacs few month ago.
>>> Obviously, I need your help.
>>> My system is composed of 2 carbon nanotubes confined between 2 graphene
>>> sheets.
>>> Closed to each graphene is a box of ionic liquids.
>>>
>>> My graphene sheets are just here in order to prevent the Ionic liquid to
>>> flow around the carbon nanotube.
>>>
>>> I did minimise my system.
>>> The person I'm taking over used to "freeze" the graphene and the CNT.
>>> In my case, I use position restrain to the carbon forming the graphene
>> and
>>> I restrain the position of the carbon forming the CNT to a plan.
>>>
>>> I did read that position restrain must be used carrefully as well.
>>>
>>> I'm realising that this systems is quite complex ...
>>> I'm tending to use a compressibility rather low (1.6e-8 bar-1) because I
>>> read that the compressibility of Ionic liquid is much more lower than the
>>> one of water.
>>> after a 500 ps simulation in order to fill the CNTs, there is like a
>> vacuum
>>> bubble above the pore.
>>>
>>> Does someone know what is happening ??
>>>
>>> Thanks in advance !
>>> Candy
>>>
>>> here is my .mpd file :
>>>
>>>
>>> ; RUN CONTROL PARAMETERS =
>>> integrator               = md
>>> ; start time and timestep in ps =
>>> tinit                    = 0
>>> dt                       = 0.0005
>>> nsteps                   = 1000000
>>> ; number of steps for center of mass motion removal =
>>> nstcomm                  = 100
>>>
>>> ; LANGEVIN DYNAMICS OPTIONS =
>>> ; Temperature, friction coefficient (amu/ps) and random seed =
>>> ; bd-temp                  = 400
>>> ; bd-fric                  = 0
>>> ; ld-seed                  = 1993
>>>
>>> ; ENERGY MINIMIZATION OPTIONS =
>>> ; Force tolerance and initial step-size =
>>> emtol                    = 10
>>> emstep                   = 0.01
>>> ; Max number of iterations in relax_shells =
>>> niter                    = 20
>>> ; Frequency of steepest descents steps when doing CG =
>>> nstcgsteep               = 1000
>>>
>>> ; OUTPUT CONTROL OPTIONS =
>>> ; Output frequency for coords (x), velocities (v) and forces (f) =
>>> nstxout                  = 500
>>> nstvout                  = 0
>>> nstfout                  = 500
>>> ; Output frequency for energies to log file and energy file =
>>> nstlog                   = 500
>>> nstenergy                = 500
>>> ; Output frequency and precision for xtc file =
>>> nstxtcout                = 500
>>> xtc-precision            = 1000
>>>
>>>
>>> ; NEIGHBORSEARCHING PARAMETERS =
>>> cutoff-scheme            = verlet
>>> verlet-buffer-tolerance  = 0.005
>>> nstlist                  = 20
>>> ; ns algorithm (simple or grid) =
>>> ns_type                  = grid
>>> ; Periodic boundary conditions: xyz or none =
>>> pbc                      = xyz
>>>
>>> periodic_molecules       = yes
>>> rlist                    = 1.0
>>> nstcalclr                = 10
>>>
>>> ; OPTIONS FOR ELECTROSTATICS AND VDW =
>>> ; Method for doing electrostatics =
>>> coulombtype              = PME
>>> coulomb-modifier         = Potential-shift
>>> rcoulomb-switch          = 0
>>> rcoulomb                 = 0.95
>>> ; Dielectric constant (DC) for cut-off or DC of reaction field =
>>> epsilon-r                = 1
>>> ; Method for doing Van der Waals =
>>> vdw-type                 = PME
>>> vdw-modifier             = Potential-shift
>>> ; cut-off lengths        =
>>> rvdw-switch              = 0
>>> rvdw                     = 0.95
>>> ; Apply long range dispersion corrections for Energy and Pressure =
>>> DispCorr                 = No
>>> ; Spacing for the PME/PPPM FFT grid =
>>> ;fourierspacing           = 0.12
>>> ; FFT grid size, when a value is 0 fourierspacing will be used =
>>> ;fourier_nx               = 0
>>> ;fourier_ny               = 0
>>> ;fourier_nz               = 0
>>> ; EWALD/PME/PPPM parameters =
>>> pme_order                = 4
>>> ewald_rtol               = 1e-05
>>> epsilon_surface          = 0
>>> optimize_fft             = no
>>>
>>> ; OPTIONS FOR WEAK COUPLING ALGORITHMS =
>>> ; Temperature coupling   =
>>> tcoupl                   = V-rescale
>>> nsttcouple               = 10
>>> ; Groups to couple separately =
>>> tc-grps                  = system
>>> ;Time constant (ps) and reference temperature (K) =
>>> tau_t                    = 0.1
>>> ref_t                    = 293.15
>>> ; Pressure coupling      =
>>> ;Pcoupl                   = no
>>> Pcoupl                   = Berendsen
>>> Pcoupltype               = semiisotropic
>>> ; Time constant (ps), compressibility (1/bar) and reference P (bar) =
>>> tau_p                    = 1.0
>>> compressibility          = 0 1.6e-8
>>> ; compressibility of ionic liquid ... 4.5e-5 for water  1.6e-8 for IL
>>> ref_p                    = 1.0 1.0
>>> nstpcouple               = 10
>>> ; SIMULATED ANNEALING CONTROL =
>>> annealing                = no
>>> ; Time at which temperature should be zero (ps) =
>>> ; zero-temp_time           = 0
>>>
>>> ; GENERATE VELOCITIES FOR STARTUP RUN =
>>> gen_vel                  = yes
>>> gen_temp                 = 300
>>> gen_seed                 = 173529
>>>
>>> energygrps               = EMI BF4 GRA C08 C16
>>> ;freezegrps               = GRA
>>> ;freezedim                = Y Y Y
>>> ;energygrp-excl           = GRA GRA GRA C04 C04 C04
>>> refcoord-scaling          = COM
>>>
>>>
>>>
>>>
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