[gmx-users] regarding rmsd calculation of protein

SHAHEE ISLAM islamshahee at gmail.com
Thu May 24 07:55:45 CEST 2018


Really thank you so much for your reply.
can i select the two chain at a time.because both protein contain 120
amino acid respectively.
then
> ri 1-120

Found 262 atoms with resind.+1 in range 1-120

 15 r_1-120             :   262 atoms

> rename Chain_A

Found 0 atoms with residue names ENAME CHAIN_A
Group is empty


On 5/24/18, Soham Sarkar <soham9038 at gmail.com> wrote:
> You should give like ri 1-120
>
> On Thu, 24 May 2018, 11:14 am SHAHEE ISLAM, <islamshahee at gmail.com> wrote:
>
>> yes its working.
>> now
>> >ri ( give numbers for residue number of each chain)
>> i have 120 amino acids of two protein each.
>> when i am giving
>> > ri 120
>>
>>
>>  15 r_120               :     2 atoms
>> should i give this in the way.
>>
>> On 5/24/18, Soham Sarkar <soham9038 at gmail.com> wrote:
>> > Put L(small)
>> > It will give the residue number
>> >
>> > On Thu, 24 May 2018, 11:00 am SHAHEE ISLAM, <islamshahee at gmail.com>
>> wrote:
>> >
>> >> after giving this command
>> >> make_ndx -f em.gro -o index.ndx
>> >> nr : group       !   'name' nr name   'splitch' nr    Enter: list
>> >> groups
>> >>  'a': atom        &   'del' nr         'splitres' nr   'l': list
>> residues
>> >>  't': atom type   |   'keep' nr        'splitat' nr    'h': help
>> >>  'r': residue         'res' nr         'chain' char
>> >>  "name": group        'case': case sensitive           'q': save and
>> quit
>> >>  'ri': residue index
>> >> these all options are shown on the screen.
>> >> but when i am giving
>> >> > |
>> >>
>> >>
>> >> Syntax error: "|"
>> >> can you please tell me what should i give.
>> >>
>> >>
>> >>
>> >>
>> >> On 5/24/18, Soham Sarkar <soham9038 at gmail.com> wrote:
>> >> > It is any .gro file of your system
>> >> > You can make index file after final md
>> >> >
>> >> > On Thu, 24 May 2018, 10:37 am SHAHEE ISLAM, <islamshahee at gmail.com>
>> >> wrote:
>> >> >
>> >> >> you have mention here em.gro,i think it is a gro file of
>> >> >> equilibration.can i make the index file after production run to
>> >> >> calculate rmsd.
>> >> >>
>> >> >> On 5/23/18, SHAHEE ISLAM <islamshahee at gmail.com> wrote:
>> >> >> > thank you so much for your quick reply.
>> >> >> >
>> >> >> > On 5/23/18, Soham Sarkar <soham9038 at gmail.com> wrote:
>> >> >> >> Do proper indexing of each chain
>> >> >> >>> make_ndx -f em.gro -o index.ndx
>> >> >> >>>l (shows total residue with number)
>> >> >> >>>ri ( give numbers for residue number of each chain)
>> >> >> >>>rename them as Chain_A and Chain_B
>> >> >> >>>v (shows the newly indexed file)
>> >> >> >>>q (save)
>> >> >> >> Now your index has two chain seperated
>> >> >> >>
>> >> >> >> On Wed, May 23, 2018 at 5:54 PM, SHAHEE ISLAM
>> >> >> >> <islamshahee at gmail.com
>> >> >
>> >> >> >> wrote:
>> >> >> >>
>> >> >> >>> hi,
>> >> >> >>> i have two protein in my gro file.when i am calculating rmsd by
>> >> >> >>> this
>> >> >> >>> command
>> >> >> >>> g_rms -s dynamic.tpr -f md_0_1_noPBC.xtc -o rmsd.xvg -tu ns
>> >> >> >>>  this options are coming
>> >> >> >>> Group     0 (         System) has 12059 elements
>> >> >> >>> Group     1 (        Protein) has   566 elements
>> >> >> >>> Group     2 (      Protein-H) has   566 elements
>> >> >> >>> Group     3 (        C-alpha) has     0 elements
>> >> >> >>> Group     4 (       Backbone) has     0 elements
>> >> >> >>> Group     5 (      MainChain) has     0 elements
>> >> >> >>> Group     6 (   MainChain+Cb) has     0 elements
>> >> >> >>> Group     7 (    MainChain+H) has     0 elements
>> >> >> >>> Group     8 (      SideChain) has   566 elements
>> >> >> >>> Group     9 (    SideChain-H) has   566 elements
>> >> >> >>> Group    10 (    Prot-Masses) has   566 elements
>> >> >> >>> Group    11 (    non-Protein) has 11493 elements
>> >> >> >>> Group    12 (          Other) has 11493 elements
>> >> >> >>> Group    13 (              W) has 11477 elements
>> >> >> >>> Group    14 (            ION) has    16 elements
>> >> >> >>> for this reason i am able to calculate the rmsd of two protein
>> >> >> >>> together by selecting 1.
>> >> >> >>> but i want to calculate the rmsd of the protein individualy.how
>> >> >> >>> i
>> >> >> >>> will
>> >> >> >>> do
>> >> >> >>> this.
>> >> >> >>> My .gro file consist of atom no 1 to 283 for protein1 and atom
>> >> >> >>> no
>> >> 284
>> >> >> >>> to 566 for protein2.
>> >> >> >>> thanking you
>> >> >> >>> shahee islam
>> >> >> >>> university of calcutta
>> >> >> >>> --
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>> >> >> >>
>> >> >> >>
>> >> >> >> --
>> >> >> >> SOHAM SARKAR
>> >> >> >> Junior Research Fellow
>> >> >> >> Department of Chemistry
>> >> >> >> INDIAN INSTITUTE OF TECHNOLOGY BOMBAY
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