[gmx-users] how to compute bending modulus of the membrane with NPs

[Li Yang]

Dear all

I'm trying to measure the bending modulus (Kc) of lipid bilayer. I've
found some papers, showing that spectral intensity needs to be
calculated using the wave vector q. This method has been applied
directly for pure membrane, or for bilayers with cholesterol.

In my simulations, there is a colloid particle immerses into the inner
or adsorbs on the surface of the lipid bilayer. I want to compute how
the interaction of particles to affect the bending modulus of the
membrane. But I'm not sure whether this method can be applied directly
in above cases? If not, how can I get it? What about the spontaneous
curvature?

Thank you very much. Any suggestion or reference will be appreciated!

Li Yang