[gmx-users] Regarding mdrunfor small organic molecules

Justin A. Lemkul jalemkul at vt.edu
Fri Aug 12 20:19:15 CEST 2011



Ravi Kumar Venkatraman wrote:
> 
> 
> Dear All,
>              When I try to grompp to generate .tpr file for mdrun from 
> topology generated by prodrg I am getting the following error.
> 
> Generated 279 of the 1225 non-bonded parameter combinations
> Excluding 3 bonded neighbours molecule type 'PRODRG'
> 
> -------------------------------------------------------
> Program grompp_d, VERSION 4.5.4
> Source code file: toppush.c, line: 1987
> 
> Fatal error:
> No such moleculetype SOL
> For more information and tips for troubleshooting, please check the GROMACS
> website at http://www.gromacs.org/Documentation/Errors
> -------------------------------------------------------
> I am herewith attaching the chlor.top file please help me findout the 
> problem.
> 

You should always check the Gromacs site and mailing list archive first.  This 
issue has come up hundreds of times and has a solution posted online:

http://www.gromacs.org/Documentation/Errors#Fatal_error.3a_No_such_moleculetype_XXX

Hint: you're missing an #include statement.

-Justin

> 
> ;
> ;       When using this software in a publication, cite:
> ;       A. W. Schuettelkopf and D. M. F. van Aalten (2004).
> ;       PRODRG - a tool for high-throughput crystallography
> ;       of protein-ligand complexes.
> ;       Acta Crystallogr. D60, 1355--1363.
> ;      
> ;      
> 
> #include "ffG43a1.itp"
> 
> [ moleculetype ]
> ; Name nrexcl
> PRODRG    3
> 
> [ atoms ]
> ;   nr      type  resnr resid  atom  cgnr   charge     mass
>      1         O     1  PDB     OAE     1   -0.6772  15.9994  
>      2         C     1  PDB     CAK     1    0.8450  12.0110  
>      3         C     1  PDB     CAG     1    0.0134  12.0110  
>      4        CL     1  PDB    CLAA     1   -0.0968  35.4530  
>      5         C     1  PDB     CAH     2    0.0134  12.0110  
>      6        CL     1  PDB    CLAB     2   -0.0968  35.4530  
>      7         C     1  PDB     CAL     2    0.8450  12.0110  
>      8         O     1  PDB     OAF     2   -0.6772  15.9994  
>      9         C     1  PDB     CAJ     2    0.0134  12.0110  
>     10        CL     1  PDB    CLAD     2   -0.0968  35.4530  
>     11         C     1  PDB     CAI     2    0.0134  12.0110  
>     12        CL     1  PDB    CLAC     3   -0.0968  35.4530  
> 
> [ bonds ]
> ; ai  aj  fu    c0, c1, ...
>    2   1   2    0.123  16600000.0    0.123  16600000.0 ;   CAK  OAE  
>    2   3   2    0.139  10800000.0    0.139  10800000.0 ;   CAK  CAG  
>    2  11   2    0.139  10800000.0    0.139  10800000.0 ;   CAK  CAI  
>    3   4   2    0.173   2928800.0    0.173   2928800.0 ;   CAG CLAA  
>    3   5   2    0.139  10800000.0    0.139  10800000.0 ;   CAG  CAH  
>    5   6   2    0.173   2928800.0    0.173   2928800.0 ;   CAH CLAB  
>    5   7   2    0.139  10800000.0    0.139  10800000.0 ;   CAH  CAL  
>    7   8   2    0.123  16600000.0    0.123  16600000.0 ;   CAL  OAF  
>    7   9   2    0.139  10800000.0    0.139  10800000.0 ;   CAL  CAJ  
>    9  10   2    0.173   2928800.0    0.173   2928800.0 ;   CAJ CLAD  
>    9  11   2    0.139  10800000.0    0.139  10800000.0 ;   CAJ  CAI  
>   11  12   2    0.173   2928800.0    0.173   2928800.0 ;   CAI CLAC  
> 
> [ pairs ]
> ; ai  aj  fu    c0, c1, ...
>    1   4   1                                           ;   OAE CLAA  
>    1   5   1                                           ;   OAE  CAH  
>    1   9   1                                           ;   OAE  CAJ  
>    1  12   1                                           ;   OAE CLAC  
>    2   6   1                                           ;   CAK CLAB  
>    2   7   1                                           ;   CAK  CAL  
>    2  10   1                                           ;   CAK CLAD  
>    3   8   1                                           ;   CAG  OAF  
>    3   9   1                                           ;   CAG  CAJ  
>    3  12   1                                           ;   CAG CLAC  
>    4   6   1                                           ;  CLAA CLAB  
>    4   7   1                                           ;  CLAA  CAL  
>    4  11   1                                           ;  CLAA  CAI  
>    5  10   1                                           ;   CAH CLAD  
>    5  11   1                                           ;   CAH  CAI  
>    6   8   1                                           ;  CLAB  OAF  
>    6   9   1                                           ;  CLAB  CAJ  
>    7  12   1                                           ;   CAL CLAC  
>    8  10   1                                           ;   OAF CLAD  
>    8  11   1                                           ;   OAF  CAI  
>   10  12   1                                           ;  CLAD CLAC  
> 
> [ angles ]
> ; ai  aj  ak  fu    c0, c1, ...
>    1   2   3   2    121.0       685.0    121.0       685.0 ;   OAE  CAK  
> CAG  
>    1   2  11   2    121.0       685.0    121.0       685.0 ;   OAE  CAK  
> CAI  
>    3   2  11   2    120.0       560.0    120.0       560.0 ;   CAG  CAK  
> CAI  
>    2   3   4   2    120.0       560.0    120.0       560.0 ;   CAK  CAG 
> CLAA  
>    2   3   5   2    120.0       560.0    120.0       560.0 ;   CAK  CAG  
> CAH  
>    4   3   5   2    120.0       560.0    120.0       560.0 ;  CLAA  CAG  
> CAH  
>    3   5   6   2    120.0       560.0    120.0       560.0 ;   CAG  CAH 
> CLAB  
>    3   5   7   2    120.0       560.0    120.0       560.0 ;   CAG  CAH  
> CAL  
>    6   5   7   2    120.0       560.0    120.0       560.0 ;  CLAB  CAH  
> CAL  
>    5   7   8   2    121.0       685.0    121.0       685.0 ;   CAH  CAL  
> OAF  
>    5   7   9   2    120.0       560.0    120.0       560.0 ;   CAH  CAL  
> CAJ  
>    8   7   9   2    121.0       685.0    121.0       685.0 ;   OAF  CAL  
> CAJ  
>    7   9  10   2    120.0       560.0    120.0       560.0 ;   CAL  CAJ 
> CLAD  
>    7   9  11   2    120.0       560.0    120.0       560.0 ;   CAL  CAJ  
> CAI  
>   10   9  11   2    120.0       560.0    120.0       560.0 ;  CLAD  CAJ  
> CAI  
>    2  11   9   2    120.0       560.0    120.0       560.0 ;   CAK  CAI  
> CAJ  
>    2  11  12   2    120.0       560.0    120.0       560.0 ;   CAK  CAI 
> CLAC  
>    9  11  12   2    120.0       560.0    120.0       560.0 ;   CAJ  CAI 
> CLAC  
> 
> [ dihedrals ]
> ; ai  aj  ak  al  fu    c0, c1, m, ...
>    2   1  11   3   2      0.0  167.4        0.0  167.4   ; imp   CAK  
> OAE  CAI  CAG  
>    3   5   4   2   2      0.0  167.4        0.0  167.4   ; imp   CAG  
> CAH CLAA  CAK  
>    5   7   6   3   2      0.0  167.4        0.0  167.4   ; imp   CAH  
> CAL CLAB  CAG  
>    7   9   8   5   2      0.0  167.4        0.0  167.4   ; imp   CAL  
> CAJ  OAF  CAH  
>    9  11  10   7   2      0.0  167.4        0.0  167.4   ; imp   CAJ  
> CAI CLAD  CAL  
>   11  12   9   2   2      0.0  167.4        0.0  167.4   ; imp   CAI 
> CLAC  CAJ  CAK  
>    2   3   5   7   2      0.0  209.3        0.0  209.3   ; imp   CAK  
> CAG  CAH  CAL  
>    3   5   7   9   2      0.0  209.3        0.0  209.3   ; imp   CAG  
> CAH  CAL  CAJ  
>    5   7   9  11   2      0.0  209.3        0.0  209.3   ; imp   CAH  
> CAL  CAJ  CAI  
>    7   9  11   2   2      0.0  209.3        0.0  209.3   ; imp   CAL  
> CAJ  CAI  CAK  
>    9  11   2   3   2      0.0  209.3        0.0  209.3   ; imp   CAJ  
> CAI  CAK  CAG  
>   11   2   3   5   2      0.0  209.3        0.0  209.3   ; imp   CAI  
> CAK  CAG  CAH  
> 
> [ system ]
> CHLORANIL BOX in water
> 
> [ molecules ]
> PRODRG          1
> SOL             17122
> 
> Thank you.
> 

-- 
========================================

Justin A. Lemkul
Ph.D. Candidate
ICTAS Doctoral Scholar
MILES-IGERT Trainee
Department of Biochemistry
Virginia Tech
Blacksburg, VA
jalemkul[at]vt.edu | (540) 231-9080
http://www.bevanlab.biochem.vt.edu/Pages/Personal/justin

========================================



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