[gmx-users] Re: Regarding mdrunfor small organic molecules

Ravi Kumar Venkatraman ravikumarvenkatraman at gmail.com
Fri Aug 12 21:48:46 CEST 2011


Dear all,
            Please can anybody send, step by step mdrun for small organic
molecules in gromacs.


> Dear All,
>              When I try to grompp to generate .tpr file for mdrun from
> topology generated by prodrg I am getting the following error.
>
> Generated 279 of the 1225 non-bonded parameter combinations
> Excluding 3 bonded neighbours molecule type 'PRODRG'
>
> -------------------------------------------------------
> Program grompp_d, VERSION 4.5.4
> Source code file: toppush.c, line: 1987
>
> Fatal error:
> No such moleculetype SOL
> For more information and tips for troubleshooting, please check the GROMACS
> website at http://www.gromacs.org/Documentation/Errors
> -------------------------------------------------------
> I am herewith attaching the chlor.top file please help me findout the
> problem.
>
>
> ;
> ;       When using this software in a publication, cite:
> ;       A. W. Schuettelkopf and D. M. F. van Aalten (2004).
> ;       PRODRG - a tool for high-throughput crystallography
> ;       of protein-ligand complexes.
> ;       Acta Crystallogr. D60, 1355--1363.
> ;
> ;
>
> #include "ffG43a1.itp"
>
> [ moleculetype ]
> ; Name nrexcl
> PRODRG    3
>
> [ atoms ]
> ;   nr      type  resnr resid  atom  cgnr   charge     mass
>      1         O     1  PDB     OAE     1   -0.6772  15.9994
>      2         C     1  PDB     CAK     1    0.8450  12.0110
>      3         C     1  PDB     CAG     1    0.0134  12.0110
>      4        CL     1  PDB    CLAA     1   -0.0968  35.4530
>      5         C     1  PDB     CAH     2    0.0134  12.0110
>      6        CL     1  PDB    CLAB     2   -0.0968  35.4530
>      7         C     1  PDB     CAL     2    0.8450  12.0110
>      8         O     1  PDB     OAF     2   -0.6772  15.9994
>      9         C     1  PDB     CAJ     2    0.0134  12.0110
>     10        CL     1  PDB    CLAD     2   -0.0968  35.4530
>     11         C     1  PDB     CAI     2    0.0134  12.0110
>     12        CL     1  PDB    CLAC     3   -0.0968  35.4530
>
> [ bonds ]
> ; ai  aj  fu    c0, c1, ...
>    2   1   2    0.123  16600000.0    0.123  16600000.0 ;   CAK  OAE
>    2   3   2    0.139  10800000.0    0.139  10800000.0 ;   CAK  CAG
>    2  11   2    0.139  10800000.0    0.139  10800000.0 ;   CAK  CAI
>    3   4   2    0.173   2928800.0    0.173   2928800.0 ;   CAG CLAA
>    3   5   2    0.139  10800000.0    0.139  10800000.0 ;   CAG  CAH
>    5   6   2    0.173   2928800.0    0.173   2928800.0 ;   CAH CLAB
>    5   7   2    0.139  10800000.0    0.139  10800000.0 ;   CAH  CAL
>    7   8   2    0.123  16600000.0    0.123  16600000.0 ;   CAL  OAF
>    7   9   2    0.139  10800000.0    0.139  10800000.0 ;   CAL  CAJ
>    9  10   2    0.173   2928800.0    0.173   2928800.0 ;   CAJ CLAD
>    9  11   2    0.139  10800000.0    0.139  10800000.0 ;   CAJ  CAI
>   11  12   2    0.173   2928800.0    0.173   2928800.0 ;   CAI CLAC
>
> [ pairs ]
> ; ai  aj  fu    c0, c1, ...
>    1   4   1                                           ;   OAE CLAA
>    1   5   1                                           ;   OAE  CAH
>    1   9   1                                           ;   OAE  CAJ
>    1  12   1                                           ;   OAE CLAC
>    2   6   1                                           ;   CAK CLAB
>    2   7   1                                           ;   CAK  CAL
>    2  10   1                                           ;   CAK CLAD
>    3   8   1                                           ;   CAG  OAF
>    3   9   1                                           ;   CAG  CAJ
>    3  12   1                                           ;   CAG CLAC
>    4   6   1                                           ;  CLAA CLAB
>    4   7   1                                           ;  CLAA  CAL
>    4  11   1                                           ;  CLAA  CAI
>    5  10   1                                           ;   CAH CLAD
>    5  11   1                                           ;   CAH  CAI
>    6   8   1                                           ;  CLAB  OAF
>    6   9   1                                           ;  CLAB  CAJ
>    7  12   1                                           ;   CAL CLAC
>    8  10   1                                           ;   OAF CLAD
>    8  11   1                                           ;   OAF  CAI
>   10  12   1                                           ;  CLAD CLAC
>
> [ angles ]
> ; ai  aj  ak  fu    c0, c1, ...
>    1   2   3   2    121.0       685.0    121.0       685.0 ;   OAE  CAK
> CAG
>    1   2  11   2    121.0       685.0    121.0       685.0 ;   OAE  CAK
> CAI
>    3   2  11   2    120.0       560.0    120.0       560.0 ;   CAG  CAK
> CAI
>    2   3   4   2    120.0       560.0    120.0       560.0 ;   CAK  CAG
> CLAA
>    2   3   5   2    120.0       560.0    120.0       560.0 ;   CAK  CAG
> CAH
>    4   3   5   2    120.0       560.0    120.0       560.0 ;  CLAA  CAG
> CAH
>    3   5   6   2    120.0       560.0    120.0       560.0 ;   CAG  CAH
> CLAB
>    3   5   7   2    120.0       560.0    120.0       560.0 ;   CAG  CAH
> CAL
>    6   5   7   2    120.0       560.0    120.0       560.0 ;  CLAB  CAH
> CAL
>    5   7   8   2    121.0       685.0    121.0       685.0 ;   CAH  CAL
> OAF
>    5   7   9   2    120.0       560.0    120.0       560.0 ;   CAH  CAL
> CAJ
>    8   7   9   2    121.0       685.0    121.0       685.0 ;   OAF  CAL
> CAJ
>    7   9  10   2    120.0       560.0    120.0       560.0 ;   CAL  CAJ
> CLAD
>    7   9  11   2    120.0       560.0    120.0       560.0 ;   CAL  CAJ
> CAI
>   10   9  11   2    120.0       560.0    120.0       560.0 ;  CLAD  CAJ
> CAI
>    2  11   9   2    120.0       560.0    120.0       560.0 ;   CAK  CAI
> CAJ
>    2  11  12   2    120.0       560.0    120.0       560.0 ;   CAK  CAI
> CLAC
>    9  11  12   2    120.0       560.0    120.0       560.0 ;   CAJ  CAI
> CLAC
>
> [ dihedrals ]
> ; ai  aj  ak  al  fu    c0, c1, m, ...
>    2   1  11   3   2      0.0  167.4        0.0  167.4   ; imp   CAK  OAE
> CAI  CAG
>    3   5   4   2   2      0.0  167.4        0.0  167.4   ; imp   CAG  CAH
> CLAA  CAK
>    5   7   6   3   2      0.0  167.4        0.0  167.4   ; imp   CAH  CAL
> CLAB  CAG
>    7   9   8   5   2      0.0  167.4        0.0  167.4   ; imp   CAL  CAJ
> OAF  CAH
>    9  11  10   7   2      0.0  167.4        0.0  167.4   ; imp   CAJ  CAI
> CLAD  CAL
>   11  12   9   2   2      0.0  167.4        0.0  167.4   ; imp   CAI CLAC
> CAJ  CAK
>    2   3   5   7   2      0.0  209.3        0.0  209.3   ; imp   CAK  CAG
> CAH  CAL
>    3   5   7   9   2      0.0  209.3        0.0  209.3   ; imp   CAG  CAH
> CAL  CAJ
>    5   7   9  11   2      0.0  209.3        0.0  209.3   ; imp   CAH  CAL
> CAJ  CAI
>    7   9  11   2   2      0.0  209.3        0.0  209.3   ; imp   CAL  CAJ
> CAI  CAK
>    9  11   2   3   2      0.0  209.3        0.0  209.3   ; imp   CAJ  CAI
> CAK  CAG
>   11   2   3   5   2      0.0  209.3        0.0  209.3   ; imp   CAI  CAK
> CAG  CAH
>
> [ system ]
> CHLORANIL BOX in water
>
> [ molecules ]
> PRODRG          1
> SOL             17122
>
> Thank you.
>
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