[gmx-users] How to install a new Forcefield in Gromacs 4.5.3

Justin A. Lemkul jalemkul at vt.edu
Fri Jan 21 03:10:10 CET 2011



Qin Qiao wrote:
> 
> 
> 2011/1/20 Justin A. Lemkul <jalemkul at vt.edu <mailto:jalemkul at vt.edu>>
> 
> 
> 
>     Qin Qiao wrote:
> 
> 
> 
>         2011/1/20 Justin A. Lemkul <jalemkul at vt.edu
>         <mailto:jalemkul at vt.edu> <mailto:jalemkul at vt.edu
>         <mailto:jalemkul at vt.edu>>>
> 
> 
> 
>            Qin Qiao wrote:
> 
> 
> 
>                2011/1/20 Justin A. Lemkul <jalemkul at vt.edu
>         <mailto:jalemkul at vt.edu>
>                <mailto:jalemkul at vt.edu <mailto:jalemkul at vt.edu>>
>         <mailto:jalemkul at vt.edu <mailto:jalemkul at vt.edu>
> 
>                <mailto:jalemkul at vt.edu <mailto:jalemkul at vt.edu>>>>
> 
> 
> 
> 
>                   Qin Qiao wrote:
> 
>                       Dear all,
> 
>                       I would like to try a new forcefield in Gromacs
>         4.5.3. What
>                       should I do after I copied the ff to
>         /share/gromacs/top
>                       directory? It seems the original FF.dat doesn't
>         exist in
>                4.5.3..
>                       Could you give me some help?
> 
> 
>                   pdb2gmx detects forcefield directories by searching
>         for names
>                that
>                   end in .ff, then looking in that directory for a
>         "forcefield.doc"
>                   file that contains a brief description of the force field.
> 
>                   -Justin
> 
> 
>                Thanks. But I cannot find the new forcefield when I used
>                pdb2gmx.. the folder of ff is named 'PACE.ff'
> 
> 
>            It must also contain a forcefield.itp file to be recognized, and
>            ultimately, to work at all.  I did a test of minimum
>         requirements,
>            and only after I added a dummy forcefield.itp file to the test.ff
>            subdirectory did pdb2gmx recognize the new force field.
> 
>            -Justin
> 
> 
>         There is an .itp file in the ff.. but it doesn't work..
>         strange.. is there any other possibility?
> 
> 
>     It works just fine for me.  To be sure, I used the name "PACE.ff"
>     instead of my generic "test.ff" to make sure capitalization or
>     something foolish wasn't a problem.  It worked fine, adding "PACE"
>     as entry 16 in the pdb2gmx menu (I also have another custom force
>     field, so the order of your pdb2gmx output may be different).
> 
>     The other thing to try is to build the force field in your working
>     directory and see if pdb2gmx finds it there.  This is, of course,
>     not strictly required (and would be very inconvenient), but it could
>     be a useful diagnostic.
> 
>     -Justin
> 
> 
> Thanks. But it doesn't work.. and I tried to copy the exact files in the 
> charmm.ff to a new test.ff, and pdb2gmx doesn't find test.ff..
> 

Do you have multiple versions of Gromacs on the same machine?  If so, are you 
calling the right pdb2gmx?

-Justin

>  
> 
>                       Best,
> 
>                       Qin
> 
> 
>                   --     ========================================
> 
>                   Justin A. Lemkul
>                   Ph.D. Candidate
>                   ICTAS Doctoral Scholar
>                   MILES-IGERT Trainee
>                   Department of Biochemistry
>                   Virginia Tech
>                   Blacksburg, VA
>                   jalemkul[at]vt.edu <http://vt.edu> <http://vt.edu>
>         <http://vt.edu> | (540)
> 
>                231-9080
> 
>                   http://www.bevanlab.biochem.vt.edu/Pages/Personal/justin
> 
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>            --     ========================================
> 
>            Justin A. Lemkul
>            Ph.D. Candidate
>            ICTAS Doctoral Scholar
>            MILES-IGERT Trainee
>            Department of Biochemistry
>            Virginia Tech
>            Blacksburg, VA
>            jalemkul[at]vt.edu <http://vt.edu> <http://vt.edu> | (540)
>         231-9080
>            http://www.bevanlab.biochem.vt.edu/Pages/Personal/justin
> 
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>     -- 
>     ========================================
> 
>     Justin A. Lemkul
>     Ph.D. Candidate
>     ICTAS Doctoral Scholar
>     MILES-IGERT Trainee
>     Department of Biochemistry
>     Virginia Tech
>     Blacksburg, VA
>     jalemkul[at]vt.edu <http://vt.edu> | (540) 231-9080
>     http://www.bevanlab.biochem.vt.edu/Pages/Personal/justin
> 
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-- 
========================================

Justin A. Lemkul
Ph.D. Candidate
ICTAS Doctoral Scholar
MILES-IGERT Trainee
Department of Biochemistry
Virginia Tech
Blacksburg, VA
jalemkul[at]vt.edu | (540) 231-9080
http://www.bevanlab.biochem.vt.edu/Pages/Personal/justin

========================================



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